| UniProt ID | FLX_ARATH | |
|---|---|---|
| UniProt AC | F4IMQ0 | |
| Protein Name | Protein FLC EXPRESSOR | |
| Gene Name | FLX | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 288 | |
| Subcellular Localization | Cytoplasm . Nucleus . homodimers present in the cytosol and heterodimers with FRI and FES1 detected only in the nucleus. | |
| Protein Description | Transactivator required for FRIGIDA-mediated activation of FLC and for the expression of the repressors of flowering AGL27/MAF1 and AGL31/MAF2. Does not alter expression of known activators of FLC expression. Not required for the photoperiod response or for the vernalization response. Not redundant with FLXL4.. | |
| Protein Sequence | MAGRDRYIPSSAVSTSSSSRLLESQLIESDRNRARSVILEDRIAIQHREIQSLLNDNQRLAVAHIGLKDQLNVAKRELERLLETAVKVKAEGEAKVREVYQNALRMEAEARVIDGLGAELGQVRSDVQRLGSDRQELATELAMFDDEMAKAKPNSDRAIEVKLEIEILRGEIRKGRAALELEKKTRASNLHHERGMEKTIDHLNREIVKLEEELVDLETKAREANAAAEAAPTPSPGLAASYGNNTDDIYGGQGRQYPEANGTHELVLREKSYVHRLVSVQLVQVSVG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 233 | Phosphorylation | AAAEAAPTPSPGLAA HHHHHCCCCCCCCHH | 30407730 | ||
| 235 | Phosphorylation | AEAAPTPSPGLAASY HHHCCCCCCCCHHHC | 30407730 | ||
| 241 | Phosphorylation | PSPGLAASYGNNTDD CCCCCHHHCCCCCCC | 30407730 | ||
| 242 | Phosphorylation | SPGLAASYGNNTDDI CCCCHHHCCCCCCCC | 30407730 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FLX_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FLX_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FLX_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| FES1_ARATH | FES1 | physical | 21282526 | |
| FRIG0_ARATH | FRI | physical | 21282526 | |
| FLX_ARATH | AT2G30120 | physical | 21282526 | |
| FIP37_ARATH | FIP37 | physical | 21798944 | |
| BH032_ARATH | BHLH32 | physical | 21798944 | |
| KNAT1_ARATH | KNAT1 | physical | 21798944 | |
| FLXL4_ARATH | AT5G61920 | physical | 23899645 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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