| UniProt ID | FAM3A_HUMAN | |
|---|---|---|
| UniProt AC | P98173 | |
| Protein Name | Protein FAM3A | |
| Gene Name | FAM3A | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 230 | |
| Subcellular Localization | Secreted . | |
| Protein Description | May act as a defensin against invading fungal microorganisms.. | |
| Protein Sequence | MRLAGPLRIVVLVVSVGVTWIVVSILLGGPGSGFPRIQQLFTSPESSVTAAPRARKYKCGLPQPCPEEHLAFRVVSGAANVIGPKICLEDKMLMSSVKDNVGRGLNIALVNGVSGELIEARAFDMWAGDVNDLLKFIRPLHEGTLVFVASYDDPATKMNEETRKLFSELGSRNAKELAFRDSWVFVGAKGVQNKSPFEQHVKNSKHSNKYEGWPEALEMEGCIPRRSTAS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 8 (in isoform 3) | Phosphorylation | - | 23.84 | 20068231 | |
| 9 (in isoform 3) | Phosphorylation | - | 3.11 | 20068231 | |
| 11 (in isoform 3) | Phosphorylation | - | 2.90 | 20068231 | |
| 58 | Ubiquitination | APRARKYKCGLPQPC CCCHHHCCCCCCCCC | 25.51 | - | |
| 85 | Ubiquitination | AANVIGPKICLEDKM CCCCCCCEEHHCCHH | 40.62 | - | |
| 98 | Ubiquitination | KMLMSSVKDNVGRGL HHHHHHHHCCCCCCH | 45.60 | - | |
| 164 | Ubiquitination | KMNEETRKLFSELGS HCCHHHHHHHHHHHH | 62.39 | - | |
| 175 | Ubiquitination | ELGSRNAKELAFRDS HHHHCCHHHHHHCCC | 57.73 | - | |
| 194 | Ubiquitination | GAKGVQNKSPFEQHV ECCCCCCCCHHHHHH | 42.27 | - | |
| 202 | Ubiquitination | SPFEQHVKNSKHSNK CHHHHHHHHCCCCCC | 54.07 | - | |
| 204 | Phosphorylation | FEQHVKNSKHSNKYE HHHHHHHCCCCCCCC | 26.48 | 26657352 | |
| 207 | Phosphorylation | HVKNSKHSNKYEGWP HHHHCCCCCCCCCCH | 38.46 | 26657352 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FAM3A_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FAM3A_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FAM3A_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| A4_HUMAN | APP | physical | 21832049 | |
| PACRL_HUMAN | PACRGL | physical | 21988832 | |
| CLC7A_HUMAN | CLEC7A | physical | 25416956 | |
| MAL2_HUMAN | MAL2 | physical | 25416956 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
