F161B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F161B_HUMAN
• UniProt AC: Q96MY7
• Protein Name: Protein FAM161B
• Gene Name: FAM161B
• Organism: Homo sapiens (Human).
• Sequence Length: 647
• Protein Sequence: MTVGRPEGAPGGAEGSRQIFPPESFADTEAGEELSGDGLVLPRASKLDEFLSPEEEIDSTSDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQCPQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWLEIHKKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENLVSLA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTVGRPEGA ------CCCCCCCCC	31.50	23532336
16	Phosphorylation	APGGAEGSRQIFPPE CCCCCCCCCCCCCCH	16.71	23532336
106	Phosphorylation	EDEEDLESFFQDKDR CCHHHHHHHHHCCCC	38.36	-
138	Ubiquitination	RCSSLNNLPSNIPRP CCHHHCCCCCCCCCC	4.84	-
170	Phosphorylation	SSWASSITVPRPFRM HHHHHHCCCCCCHHH	26.80	24719451
178	Phosphorylation	VPRPFRMTLREARKK CCCCHHHHHHHHHHH	20.57	-
254	Phosphorylation	KRKELLLSSLKPFSF HHHHHHHHCCCCCCH	33.33	24719451
280	Phosphorylation	RQRDLAATAEAKISK HHHHHHHHHHHHHHH	21.30	24505115
286	Phosphorylation	ATAEAKISKQKATRR HHHHHHHHHHHHHCC	28.47	24505115
331	Phosphorylation	DMLQMASSPIASSSN HHHHHHHCCCCCCCC	15.70	-
337	Phosphorylation	SSPIASSSNRANPQP HCCCCCCCCCCCCCC	28.04	-
380	Ubiquitination	PDYEGLYKAFQRRAA CCHHHHHHHHHHHHH	48.01	-
426	Phosphorylation	TTGRRQDSPQPPATP CCCCCCCCCCCCCCC	19.66	30631047
432	Phosphorylation	DSPQPPATPLPRSRS CCCCCCCCCCCCCCC	31.00	30631047
437	Phosphorylation	PATPLPRSRSLSGLA CCCCCCCCCCCHHHH	25.04	27966365
439	Phosphorylation	TPLPRSRSLSGLASL CCCCCCCCCHHHHHC	28.29	25849741
441	Phosphorylation	LPRSRSLSGLASLSA CCCCCCCHHHHHCCC	32.76	23312004
443	Ubiquitination	RSRSLSGLASLSANT CCCCCHHHHHCCCCC	2.35	-
445	Phosphorylation	RSLSGLASLSANTLP CCCHHHHHCCCCCCC	28.09	23312004
447	Phosphorylation	LSGLASLSANTLPVH CHHHHHCCCCCCCEE	19.58	23312004
450	Phosphorylation	LASLSANTLPVHITD HHHCCCCCCCEECCH	31.96	23312004
456	Phosphorylation	NTLPVHITDATRKRE CCCCEECCHHHHHHH	12.52	23312004
459	Phosphorylation	PVHITDATRKRESAV CEECCHHHHHHHHHH	39.26	23312004
468	Phosphorylation	KRESAVRSALEKKNK HHHHHHHHHHHHHCH	30.52	21964256
496	Phosphorylation	KSQAMSKSVTLRAKA HHHHCCHHHHHHHHH	17.02	23909892
498	Phosphorylation	QAMSKSVTLRAKAMD HHCCHHHHHHHHHCC	20.02	24719451
500	Phosphorylation	MSKSVTLRAKAMDPH CCHHHHHHHHHCCCC	25.36	27251275
509	Phosphorylation	KAMDPHKSLEEVFKA HHCCCCCCHHHHHHH	37.67	30622161
527	Acetylation	ENRNNDRKRAKEYKK HHCCHHHHHHHHHHH	60.62	20167786
532	Phosphorylation	DRKRAKEYKKELEEM HHHHHHHHHHHHHHH	27.01	22817900
578	Ubiquitination	KQAGLEEDFVRNKGQ HHCCCHHHHHHCCCC	37.66	-
580	Ubiquitination	AGLEEDFVRNKGQGT CCCHHHHHHCCCCCC	11.59	-
590	Acetylation	KGQGTRAVQEKETKI CCCCCHHHHCHHHHC	7.33	-
621	O-linked_Glycosylation	PEQGLEGSLEQPASP HHHCCCCCCCCCCCH	21.25	30379171
627	Phosphorylation	GSLEQPASPRKVLEE CCCCCCCCHHHHHHH	31.74	25056879
690	Phosphorylation	-------------------------------------------------- --------------------------------------------------		27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F161B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F161B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F161B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KLH15_HUMAN	KLHL15	physical	28514442
ACAD8_HUMAN	ACAD8	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.