ETA2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ETA2_SCHPO
• UniProt AC: O14108
• Protein Name: DNA-binding protein eta2
• Gene Name: eta2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 569
• Subcellular Localization: Nucleus.
• Protein Sequence: MMLAIDMTINENQGTRSNLESPTLSCSSKGAMQERDVMFTDHNTFNITNNKSRPGSLMKSMKRKDVYEFDEDNEFEFEMGSLIHKPSRAHSLGGTSEPVSDDHKDCMEATRQLLENSPLSSVVVKTCSDHASKRKIARSSSDDSESKVESTNSFNAKKRKDAWTEEHEKWFQARIDELLTIRSISREQMIEILEDEHAGSRLQGFLESVASFLNRKENSLLKYMRAFFQVAGYEKIDIGSLAAEEDSQLNFSLEDAQVIQKVVLSYCNNEGVDLQEFGFRMSSSSLRHTNINFLYNELRELLPTSISRKGIIRYLKEIYKPLDPKDRNAWEESELKKLYTLVEQEGTRWNSIANKLGTSPAACMSQWRFVVGTSTQETIDRRKLWTNEEEAKLLDLVKSSYRSSFHTKKMTSLFTHNNHTTSNIQREIPASDSIAWHSISKKLGTKSPESCRKQYEKTIASYSSNQRQEEDQGKKRKKRKKKKSKGKRKFYVADSLKLLEHVQRQCGEAISINAIDWKGIVKQMPKWSEEELRAQATNLVASVRGWKKTRLSESVRIAITDLKSLPPDV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	GTRSNLESPTLSCSS CCCCCCCCCCCCCCC	26.76	28889911
140	Phosphorylation	KRKIARSSSDDSESK HHHHHCCCCCCCHHH	32.03	21712547
461	Phosphorylation	QYEKTIASYSSNQRQ HHHHHHHHHCCCHHH	23.00	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ETA2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ETA2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ETA2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YJ03_SCHPO	rhn1	genetic	18818364
TPS1_SCHPO	tps1	genetic	22681890
THI5_SCHPO	thi5	genetic	22681890
RR14N_SCHPO	rrp14	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, AND MASSSPECTROMETRY.
PubMed: 18257517