| UniProt ID | EID2B_HUMAN | |
|---|---|---|
| UniProt AC | Q96D98 | |
| Protein Name | EP300-interacting inhibitor of differentiation 2B | |
| Gene Name | EID2B {ECO:0000312|EMBL:AAH09725.2} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 161 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Acts as a repressor of MYOD-dependent transcription, glucocorticoid receptor-dependent transcription, and muscle differentiation.. | |
| Protein Sequence | MAEPTGLLEMSELPGDSSVPQVGTASGVSDVLRGAVGGGVRVQEAREGPVAEAARSMARMPGPVPGPIPSSVPGLASAPDPHQQLAFLEINRQLLFREYLDGSSMIPVRLLRDFEERRRLFVEGCKAREAAFDADPPQMDFAAVAFTVALTASEALSPLAD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 99 | Phosphorylation | RQLLFREYLDGSSMI HHHHHHHHHCCCCCE | 13.06 | 30576142 | |
| 103 | Phosphorylation | FREYLDGSSMIPVRL HHHHHCCCCCEEHHH | 19.19 | 30576142 | |
| 126 | Ubiquitination | RLFVEGCKAREAAFD HHHHHHHHHHHHHHC | 62.43 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of EID2B_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of EID2B_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of EID2B_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MAGE1_HUMAN | MAGEE1 | physical | 26186194 | |
| SHPK_HUMAN | SHPK | physical | 26186194 | |
| MAGE1_HUMAN | MAGEE1 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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