EID2B_HUMAN - dbPTM
EID2B_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID EID2B_HUMAN
UniProt AC Q96D98
Protein Name EP300-interacting inhibitor of differentiation 2B
Gene Name EID2B {ECO:0000312|EMBL:AAH09725.2}
Organism Homo sapiens (Human).
Sequence Length 161
Subcellular Localization Nucleus .
Protein Description Acts as a repressor of MYOD-dependent transcription, glucocorticoid receptor-dependent transcription, and muscle differentiation..
Protein Sequence MAEPTGLLEMSELPGDSSVPQVGTASGVSDVLRGAVGGGVRVQEAREGPVAEAARSMARMPGPVPGPIPSSVPGLASAPDPHQQLAFLEINRQLLFREYLDGSSMIPVRLLRDFEERRRLFVEGCKAREAAFDADPPQMDFAAVAFTVALTASEALSPLAD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
99PhosphorylationRQLLFREYLDGSSMI
HHHHHHHHHCCCCCE
13.0630576142
103PhosphorylationFREYLDGSSMIPVRL
HHHHHCCCCCEEHHH
19.1930576142
126UbiquitinationRLFVEGCKAREAAFD
HHHHHHHHHHHHHHC
62.43-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of EID2B_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of EID2B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of EID2B_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MAGE1_HUMANMAGEE1physical
26186194
SHPK_HUMANSHPKphysical
26186194
MAGE1_HUMANMAGEE1physical
28514442

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of EID2B_HUMAN

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Related Literatures of Post-Translational Modification

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