UniProt ID | DRD1_RAT | |
---|---|---|
UniProt AC | P18901 | |
Protein Name | D(1A) dopamine receptor | |
Gene Name | Drd1 | |
Organism | Rattus norvegicus (Rat). | |
Sequence Length | 446 | |
Subcellular Localization |
Cell membrane Multi-pass membrane protein . Endoplasmic reticulum membrane Multi-pass membrane protein . Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. |
|
Protein Description | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.. | |
Protein Sequence | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
4 | N-linked_Glycosylation | ----MAPNTSTMDEA ----CCCCCCCCCCC | 36.80 | - | |
256 | Phosphorylation | NPVECAQSESSFKMS CCCHHHCCCCCCCCC | 22.41 | 22817900 | |
258 | Phosphorylation | VECAQSESSFKMSFK CHHHCCCCCCCCCCH | 46.45 | 22817900 | |
259 | Phosphorylation | ECAQSESSFKMSFKR HHHCCCCCCCCCCHH | 25.49 | 22817900 | |
268 | Phosphorylation | KMSFKRETKVLKTLS CCCCHHHHHHHHHHH | 30.41 | 22817900 | |
347 | S-palmitoylation | AFSTLLGCYRLCPTT HHHHHHHHHHHCCCC | 1.48 | - | |
351 | S-palmitoylation | LLGCYRLCPTTNNAI HHHHHHHCCCCCCCE | 1.76 | - | |
398 | Phosphorylation | IPHAVGSSEDLKKEE ECCCCCCCHHHHHHH | 29.24 | 30411139 | |
421 | Phosphorylation | EKLSPALSVILDYDT HHHCHHHHHHCCCCC | 14.82 | - | |
428 | Phosphorylation | SVILDYDTDVSLEKI HHHCCCCCCCCHHHC | 31.88 | 22817900 | |
431 | Phosphorylation | LDYDTDVSLEKIQPV CCCCCCCCHHHCCCC | 33.35 | 22817900 | |
439 | Phosphorylation | LEKIQPVTHSGQHST HHHCCCCCCCCCCCC | 19.60 | 27097102 | |
441 | Phosphorylation | KIQPVTHSGQHST-- HCCCCCCCCCCCC-- | 30.68 | 27097102 | |
445 | Phosphorylation | VTHSGQHST------ CCCCCCCCC------ | 28.11 | 27097102 | |
446 | Phosphorylation | THSGQHST------- CCCCCCCC------- | 40.27 | 27097102 |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DRD1_RAT !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DRD1_RAT !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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