DLX4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DLX4_HUMAN
• UniProt AC: Q92988
• Protein Name: Homeobox protein DLX-4
• Gene Name: DLX4
• Organism: Homo sapiens (Human).
• Sequence Length: 240
• Subcellular Localization: Nucleus .
• Protein Description: May play a role in determining the production of hemoglobin S. May act as a repressor. During embryonic development, plays a role in palatogenesis..
• Protein Sequence: MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTSLPCPLP ------CCCCCCCCC	38.68	-
3	Phosphorylation	-----MTSLPCPLPG -----CCCCCCCCCC	29.08	-
14	Phosphorylation	PLPGRDASKAVFPDL CCCCCCHHHHCCCCC	25.99	-
96	Phosphorylation	PQELEADSEKPRLSP HHHHHCCCCCCCCCC	55.35	-
198	Phosphorylation	TFSVSPCSPPLPSLW EEEECCCCCCCCCHH	32.70	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DLX4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DLX4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DLX4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LSM3_HUMAN	LSM3	physical	21988832
GPC6_HUMAN	GPC6	physical	28514442
RRP44_HUMAN	DIS3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.