DA1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DA1_ARATH
• UniProt AC: P0C7Q8
• Protein Name: Protein DA1
• Gene Name: DA1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 532
• Protein Description: Ubiquitin receptor that limits final seed and organ size by restricting the period of cell proliferation. May act maternally to control seed mass..
• Protein Sequence: MGWFNKIFKGSNQRLRVGNNKHNHNVYYDNYPTASHDDEPSAADTDADNDEPHHTQEPSTSEDNTSNDQENEDIDRAIALSLLEENQEQTSISGKYSMPVDEDEQLARALQESMVVGNSPRHKSGSTYDNGNAYGAGDLYGNGHMYGGGNVYANGDIYYPRPITFQMDFRICAGCNMEIGHGRFLNCLNSLWHPECFRCYGCSQPISEYEFSTSGNYPFHKACYRERYHPKCDVCSHFIPTNHAGLIEYRAHPFWVQKYCPSHEHDATPRCCSCERMEPRNTRYVELNDGRKLCLECLDSAVMDTMQCQPLYLQIQNFYEGLNMKVEQEVPLLLVERQALNEAREGEKNGHYHMPETRGLCLSEEQTVSTVRKRSKHGTGKWAGNITEPYKLTRQCEVTAILILFGLPRLLTGSILAHEMMHAWMRLKGFRTLSQDVEEGICQVMAHKWLDAELAAGSTNSNAASSSSSSQGLKKGPRSQYERKLGEFFKHQIESDASPVYGDGFRAGRLAVHKYGLRKTLEHIQMTGRFPV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
119	Phosphorylation	ESMVVGNSPRHKSGS HHCCCCCCCCCCCCC	19.85	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DA1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
95	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503
221	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503
348	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503
376	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503
381	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503
391	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503
474	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503
475	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503
519	K	ubiquitylation	Ubiquitinated at LYS-95, LYS-221, LYS-348, LYS-376, LYS-381, LYS-391, LYS-474, LYS-475 and LYS-519 by the E3 ubiquitin-protein ligases BB and DA2.	28167503

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DA1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TCP14_ARATH	TCP14	physical	25757472
TCP15_ARATH	AT1G69690	physical	25757472
SAP_ARATH	SAP	genetic	27048938

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.