CYCL_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CYCL_DROME
• UniProt AC: O61734
• Protein Name: Protein cycle
• Gene Name: cyc
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 413
• Subcellular Localization: Nucleus .
• Protein Description: Putative transcription factor involved in the generation of biological rhythms. Activates cycling transcription of Period (PER) and Timeless (TIM) by binding to the E-box (5'-CACGTG-3') present in their promoters..
• Protein Sequence: MEVQEFCENMEEIEDENYDEEKSARTSDENRKQNHSEIEKRRRDKMNTYINELSSMIPMCFAMQRKLDKLTVLRMAVQHLRGIRGSGSLHPFNGSDYRPSFLSDQELKMIILQASEGFLFVVGCDRGRILYVSDSVSSVLNSTQADLLGQSWFDVLHPKDIGKVKEQLSSLEQCPRERLIDAKTMLPVKTDVPQSLCRLCPGARRSFFCRMKLRTASNNQIKEESDTSSSSRSSTKRKSRLTTGHKYRVIQCTGYLKSWTPIKDEDQDADSDEQTTNLSCLVAIGRIPPNVRNSTVPASLDNHPNIRHVLFISRHSGEGKFLFIDQRATLVIGFLPQEILGTSFYEYFHNEDIAALMESHKMVMQVPEKVTTQVYRFRCKDNSYIQLQSEWRAFKNPWTSEIDYIIAKNSVFL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of CYCL_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CYCL_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CYCL_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CYCL_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ANXB9_DROME	AnxB9	physical	15710747
PER_DROME	per	physical	10409723
TIM_DROME	tim	physical	10409723
CLOCK_DROME	Clk	physical	23847101
CLOCK_DROME	Clk	physical	23935523
CLOCK_DROME	Clk	physical	27489346
CLOCK_DROME	Clk	physical	10417378

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.