CXL14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CXL14_HUMAN
• UniProt AC: O95715
• Protein Name: C-X-C motif chemokine 14
• Gene Name: CXCL14
• Organism: Homo sapiens (Human).
• Sequence Length: 111
• Subcellular Localization: Secreted.
• Protein Description: Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays..
• Protein Sequence: MSLLPRRAPPVSMRLLAAALLLLLLALYTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSLLPRRAP ------CCCCCCCCC	38.32	22210691
12	Phosphorylation	PRRAPPVSMRLLAAA CCCCCCHHHHHHHHH	12.17	-
72	Phosphorylation	EKMVIITTKSVSRYR CCEEEEEECCHHHHC	15.77	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CXL14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CXL14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CXL14_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
REL_HUMAN	REL	physical	21988832
TEX11_HUMAN	TEX11	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.