| UniProt ID | CXB3_MOUSE | |
|---|---|---|
| UniProt AC | P28231 | |
| Protein Name | Gap junction beta-3 protein | |
| Gene Name | Gjb3 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 270 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein. Cell junction, gap junction. |
|
| Protein Description | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.. | |
| Protein Sequence | MDWKKLQDLLSGVNQYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTRQPGCTNVCYDNFFPISNIRLWALQLIFVTCPSMLVILHVAYREERERKHRQKHGEQCAKLYSHPGKKHGGLWWTYLFSLIFKLIIELVFLYVLHTLWHGFTMPRLVQCASIVPCPNTVDCYIARPTEKKVFTYFMVGASAVCIILTICEICYLIFHRIMRGISKGKSTKSISSPKSSSRASTCRCHHKLLESGDPEADPASEKLQASAPSLTPI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 11 | Phosphorylation | KKLQDLLSGVNQYST HHHHHHHHHHHHHHH | 48.25 | 29899451 | |
| 231 | Ubiquitination | TKSISSPKSSSRAST CCCCCCCCCCCCCCC | 65.99 | - | |
| 263 | Phosphorylation | ASEKLQASAPSLTPI HHHHHHHCCCCCCCC | 27.96 | 22817900 | |
| 266 | Phosphorylation | KLQASAPSLTPI--- HHHHCCCCCCCC--- | 44.59 | 29895711 | |
| 268 | Phosphorylation | QASAPSLTPI----- HHCCCCCCCC----- | 24.23 | 22006019 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CXB3_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CXB3_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CXB3_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CXB2_MOUSE | Gjb2 | physical | 19050930 | |
| CXB6_MOUSE | Gjb6 | physical | 19050930 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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