CV046_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CV046_HUMAN
• UniProt AC: C9J442
• Protein Name: Uncharacterized protein C22orf46
• Gene Name: C22orf46
• Organism: Homo sapiens (Human).
• Sequence Length: 243
• Subcellular Localization: Secreted .
• Protein Sequence: MLLSLLGACAVVGPFHGPEWEPVQGLLSQNHSCRDPQCCGNLLVLCLFLVWQVRHCWHQVTRTRFSTRNVIKVPLQKRAVPSMRCETVFKLTPEFFSPGKSRGLDSQQCAQRQRWGYRRSLQESWAQNLLSPQHPCPGPPSGVHTHSEPIFCTTSISNTCLLPQNSSWKAWQVPWCLHDGQTRPALDMCQEMEQLLLHSQERLVSLEPVISVRSRPTSMTLTTSLPNLLSAERLQFCPQRAPA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	N-linked_Glycosylation	VQGLLSQNHSCRDPQ CCHHHHCCCCCCCCC	26.18	UniProtKB CARBOHYD
63	Phosphorylation	CWHQVTRTRFSTRNV HHHHHHCCCCCCCCE	27.05	26074081
66	Phosphorylation	QVTRTRFSTRNVIKV HHHCCCCCCCCEEEE	24.14	26074081
67	Phosphorylation	VTRTRFSTRNVIKVP HHCCCCCCCCEEEEE	24.45	26074081
165	N-linked_Glycosylation	NTCLLPQNSSWKAWQ CCEECCCCCCCCCEE	35.75	UniProtKB CARBOHYD
224	Phosphorylation	TSMTLTTSLPNLLSA CCCEEECCCCCCCCH	36.27	-
230	Phosphorylation	TSLPNLLSAERLQFC CCCCCCCCHHHHHCC	31.11	20860994

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CV046_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CV046_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CV046_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
K1C40_HUMAN	KRT40	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.