CSK2P_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CSK2P_ARATH
• UniProt AC: O64816
• Protein Name: Casein kinase II subunit alpha-4, chloroplastic {ECO:0000305}
• Gene Name: CKA4 {ECO:0000303|PubMed:26025542}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 432
• Subcellular Localization: Plastid, chloroplast .
• Protein Description: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site (By similarity). Involved in the regulation of various developmental processes. [PubMed: 26025542 Involved in the regulation of plant growth and flowering time]
• Protein Sequence: MALRPCTGFTISSLRNASAANNNLFSLLSFSSSSPAKRNLLLSSLQDNLRRFASSASLYRQHLRNQQQQHQQQQQSRVKEKSETLAQKIGKSIRRAGAPSKARVYADVNVVRPKDYWDYESLAVQWGVQDDYEVVRKVGRGKYSEVFEGIHATDNEKCVIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEHVNNKDFKVLYPTLSDYDVRYYIFELLKALDFCHSRGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDLWSLGCMFAGMIFRKEPFFYGHDNYDQLVKIAKVLGTDELNAYLNKYRIELDPNLTSLVGRHSRKPWTKFINSENQHLAVPEAVDFVDKLLRYDHQERPTAKEAMAHPYFYPIRNAESSRTPRSQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
82	Phosphorylation	QSRVKEKSETLAQKI HHHHHHHHHHHHHHH	36.58	22074104
84	Phosphorylation	RVKEKSETLAQKIGK HHHHHHHHHHHHHHH	34.19	22074104
116	Phosphorylation	NVVRPKDYWDYESLA EEECCHHHCCHHHHH	13.30	23111157
132	Phosphorylation	QWGVQDDYEVVRKVG HHCCCCCHHHHHHHC	20.93	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CSK2P_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CSK2P_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CSK2P_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ASIL2_ARATH	AT3G14180	physical	21798944
SIGA_ARATH	SIGA	physical	21071627
RAA1A_ARATH	ARA-2	physical	24833385
DHAR1_ARATH	DHAR1	physical	24833385
WNK3_ARATH	WNK3	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.