UniProt ID | CRCM1_DROME | |
---|---|---|
UniProt AC | Q9U6B8 | |
Protein Name | Calcium release-activated calcium channel protein 1 | |
Gene Name | olf186-F | |
Organism | Drosophila melanogaster (Fruit fly). | |
Sequence Length | 351 | |
Subcellular Localization |
Cell membrane Multi-pass membrane protein. |
|
Protein Description | Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores. Regulates transcription factor NFAT nuclear import.. | |
Protein Sequence | MSVWTTANNSGLETPTKSPITSSVPRAARSSAVITTGNHQQHHFQHVVAAAVAAATSVATGHQFQQQFPLHAHPHPQHHSNSPTGSGSNSNNSAGFQRTSISNSLLQFPPPPPPSSQNQAKPRGHHRTASSSMSQSGEDLHSPTYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQLDHDTNVPPGMLIAFAICTTLLVAVHMLALMISTCILPNIETVCNLHSISLVHESPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSPPAAWSACVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHHNNIRNNGMNYGASGDIV | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
83 (in isoform 3) | Phosphorylation | - | 45.06 | 23607784 | |
85 (in isoform 3) | Phosphorylation | - | 33.13 | 29892262 | |
86 (in isoform 3) | Phosphorylation | - | 41.34 | 29892262 | |
134 | Phosphorylation | RTASSSMSQSGEDLH CCCCCCCCCCCCCCC | 24.12 | 19429919 | |
136 | Phosphorylation | ASSSMSQSGEDLHSP CCCCCCCCCCCCCCC | 36.52 | 19429919 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CRCM1_DROME !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CRCM1_DROME !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CRCM1_DROME !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
GSC_DROME | Gsc | physical | 14605208 | |
STIM_DROME | Stim | physical | 16921385 | |
STIM_DROME | Stim | physical | 27591258 | |
CRCM1_DROME | olf186-F | physical | 23180775 | |
CRCM1_DROME | olf186-F | physical | 18820677 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
loading...