CRCM1_DROME - dbPTM
CRCM1_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CRCM1_DROME
UniProt AC Q9U6B8
Protein Name Calcium release-activated calcium channel protein 1
Gene Name olf186-F
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 351
Subcellular Localization Cell membrane
Multi-pass membrane protein.
Protein Description Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores. Regulates transcription factor NFAT nuclear import..
Protein Sequence MSVWTTANNSGLETPTKSPITSSVPRAARSSAVITTGNHQQHHFQHVVAAAVAAATSVATGHQFQQQFPLHAHPHPQHHSNSPTGSGSNSNNSAGFQRTSISNSLLQFPPPPPPSSQNQAKPRGHHRTASSSMSQSGEDLHSPTYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQLDHDTNVPPGMLIAFAICTTLLVAVHMLALMISTCILPNIETVCNLHSISLVHESPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSPPAAWSACVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHHNNIRNNGMNYGASGDIV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
83 (in isoform 3)Phosphorylation-45.0623607784
85 (in isoform 3)Phosphorylation-33.1329892262
86 (in isoform 3)Phosphorylation-41.3429892262
134PhosphorylationRTASSSMSQSGEDLH
CCCCCCCCCCCCCCC
24.1219429919
136PhosphorylationASSSMSQSGEDLHSP
CCCCCCCCCCCCCCC
36.5219429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CRCM1_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CRCM1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CRCM1_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GSC_DROMEGscphysical
14605208
STIM_DROMEStimphysical
16921385
STIM_DROMEStimphysical
27591258
CRCM1_DROMEolf186-Fphysical
23180775
CRCM1_DROMEolf186-Fphysical
18820677

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CRCM1_DROME

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Related Literatures of Post-Translational Modification

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