UniProt ID | CP2D6_HUMAN | |
---|---|---|
UniProt AC | P10635 | |
Protein Name | Cytochrome P450 2D6 | |
Gene Name | CYP2D6 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 497 | |
Subcellular Localization |
Endoplasmic reticulum membrane Peripheral membrane protein. Microsome membrane Peripheral membrane protein. |
|
Protein Description | Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.. | |
Protein Sequence | MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
116 (in isoform 2) | Phosphorylation | - | 34.13 | - | |
124 | Phosphorylation | QGVFLARYGPAWREQ HCEEEEECCHHHHHH | 23.12 | - | |
135 | Phosphorylation | WREQRRFSVSTLRNL HHHHHCCCHHHHHHC | 17.22 | 20166139 | |
137 | Phosphorylation | EQRRFSVSTLRNLGL HHHCCCHHHHHHCCC | 22.11 | 25072903 | |
138 | Phosphorylation | QRRFSVSTLRNLGLG HHCCCHHHHHHCCCC | 27.81 | 25072903 | |
183 | Phosphorylation | GLLDKAVSNVIASLT CHHHHHHHHHHHHHH | 30.18 | - | |
217 | Phosphorylation | QEGLKEESGFLREVL HHHHHHCCCHHHHHH | 35.62 | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CP2D6_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CP2D6_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CP2D6_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
NCPR_HUMAN | POR | physical | 15680923 | |
CP2D6_HUMAN | CYP2D6 | physical | 22308038 | |
CP2D6_HUMAN | CYP2D6 | physical | 16352597 |
Kegg Disease | |
---|---|
There are no disease associations of PTM sites. | |
OMIM Disease | |
There are no disease associations of PTM sites. | |
Kegg Drug | |
D00068 | Anhydrous ethanol (JP16); Alcohol (USP); Dehydrated ethanol; Ethyl alcohol; Dehydrated ethanol (TN) |
D00110 | Cocaine (USP); Cocaine (TN) |
D00136 | Haloperidol (JP16/USP/INN); Haldol (TN) |
D00195 | Codeine (USP); Codeine hydrate |
D00199 | Ajmaline (JP16); Ajimalin (TN) |
D00211 | Rifampicin (JP16/INN); Rifampin (USP); Rifadin (TN); Rimactane (TN) |
D00217 | Acetaminophen (JP16/USP); Paracetamol (INN); Tylenol (TN) |
D00228 | Amoxapine (JP16/USP/INN); Asendin (TN) |
D00235 | Atenolol (JP16/USP/INN); Tenormin (TN) |
D00255 | Carvedilol (JAN/USAN/INN); Artist (TN); Coreg (TN) |
D00270 | Chlorpromazine (USP/INN); Thorazine (TN) |
D00283 | Clozapine (JAN/USP/INN); Clozaril (TN) |
D00292 | Dexamethasone (JP16/USP/INN); Decadron (TN); Maxidex (TN) |
D00295 | Cimetidine (JP16/USP/INN); Tagamet (TN) |
D00300 | Diphenhydramine (JP16/INN); Restamin (TN) |
D00326 | Fluoxetine (USAN/INN); Fluoxetine (TN) |
D00358 | Lidocaine (JP16/USP/INN); Dentipatch (TN); Xylocaine (TN) |
D00364 | Loratadine (JAN/USAN/INN); Claritin (TN) |
D00373 | Thioridazine (USP/INN); Mellaril-S (TN) |
D00378 | Timolol (USAN); Timolol hemihydrate; Betimol (TN) |
D00394 | Trimipramine (USAN/INN) |
D00403 | Levomepromazine (USAN/INN); Methotrimeprazine (USP); Levoprome (TN) |
D00422 | Ranitidine (USAN/INN); Ranitidine (TN) |
D00426 | Risperidone (JP16/USAN/INN); Risperdal (TN) |
D00427 | Ritonavir (JAN/USAN/INN); Norvir (TN) |
D00454 | Olanzapine (JAN/USAN/INN); Zyprexa (TN) |
D00456 | Ondansetron (JAN/USP/INN); Zofran ODT (TN) |
D00480 | Promethazine hydrochloride (JP16/USP); Phenergan (TN); Promethegan (TN) |
D00483 | Propranolol hydrochloride (JP16/USP); Inderal (TN); Innopran XL (TN) |
D00484 | Protriptyline hydrochloride (USP); Vivactil (TN) |
D00485 | Pseudoephedrine hydrochloride (USP); Sudafed (TN) |
D00494 | Promethazine (JAN/INN) |
D00502 | Pergolide mesilate (JAN); Pergolide mesylate (USP); Permax (TN) |
D00503 | Perphenazine (JP16/USP/INN); Trilafon (TN) |
D00513 | Pindolol (JP16/USP/INN); Blocklin-L (TN); Carvisken (TN); Visken (TN) |
D00560 | Pimozide (JP16/USP/INN); Orap (TN) |
D00563 | Mirtazapine (JAN/USAN/INN); Remeron (TN); Reflex (TN) |
D00567 | Celecoxib (JAN/USAN/INN); Celebrex (TN) |
D00569 | Phenacetin (JAN/INN) |
D00599 | Carteolol hydrochloride (JP16/USP); Cartrol (TN); Ocupress (TN) |
D00601 | Metoprolol tartrate (JP16/USP); Lopressor (TN) |
D00603 | Timolol maleate (JP16/USP); Blocadren (TN); Istalol (TN); Timoptic (TN) |
D00616 | Diltiazem hydrochloride (JP16/USP); Cardizem (TN); Cartia XT (TN); Dilacor XR (TN); Dilt-CD (TN) |
D00619 | Verapamil hydrochloride (JP16/USP); Calan (TN); Covera-hs (TN); Vasolan (TN); Verelan (TN) |
D00631 | Bepridil hydrochloride hydrate (JAN); Bepridil hydrochloride (USAN); Vascor (TN) |
D00635 | Metoprolol succinate (USP); Toprol XL (TN) |
D00636 | Amiodarone hydrochloride (JP16/USAN); Ancaron (TN); Cordarone (TN) |
D00638 | Flecainide acetate (JP16/USP); Tambocor (TN) |
D00639 | Mexiletine hydrochloride (JP16/USP); Mexitil (TN) |
D00640 | Propafenone hydrochloride (JP16/USP); Rythmol (TN) |
D00642 | Quinidine gluconate (USP); Quinaglute (TN) |
D00643 | Quinidine polygalacturonate; Cardioquin (TN) |
D00646 | Tolterodine (USAN/INN) |
D00661 | Cevimeline hydrochloride hydrate (JAN); Cevimeline hydrochloride (USAN); Evoxac (TN); Saligren (TN) |
D00665 | Chlorpheniramine maleate (JP16/USP); Chlor-trimeton (TN); Teldrin (TN) |
D00666 | Clemastine fumarate (JP16/USP); Tavist (TN) |
D00668 | d-Chlorpheniramine maleate (JP16); Dexchlorpheniramine maleate (USP); Mylaramine (TN); Polaramine (T |
D00669 | Diphenhydramine hydrochloride (JP16/USP); Benadryl (TN) |
D00670 | Donepezil hydrochloride (JP16/USAN); Aricept (TN) |
D00672 | Hydroxyzine hydrochloride (JP16/USP); Atarax (TN); Vistaril (TN) |
D00673 | Ranitidine hydrochloride (JP16/USP); Zantac (TN) |
D00674 | Naratriptan hydrochloride (JAN/USAN); Amerge (TN) |
D00678 | Ondansetron hydrochloride hydrate (JAN/USP); Ondansetron hydrochloride; Zofran (TN) |
D00726 | Metoclopramide (JP16/INN); Elieten (TN); Terperan (TN) |
D00749 | Leflunomide (JAN/USAN/INN); Arava (TN) |
D00785 | Selegiline hydrochloride (JAN/USP); Eldepryl (TN) |
D00789 | Chlorpromazine hydrochloride (JP16/USP); Sonazine (TN) |
D00791 | Fluphenazine hydrochloride (JAN/USP); Prolixin (TN) |
D00793 | Fluphenazine decanoate (JAN/USP); Prolixin decanoate (TN) |
D00798 | Thioridazine hydrochloride (JP16/USP); Mellaril (TN) |
D00809 | Amitriptyline hydrochloride (JP16/USP); Elavil (TN) |
D00811 | Clomipramine hydrochloride (JP16/USP); Anafranil (TN) |
D00812 | Desipramine hydrochloride (JAN/USP); Norpramin (TN) |
D00814 | Doxepin hydrochloride (USP); Sinequan (TN); Zonalon (TN) |
D00815 | Imipramine hydrochloride (JP16/USP); Tofranil (TN) |
D00816 | Nortriptyline hydrochloride (JP16/USP/INN); Pamelor (TN) |
D00817 | Bupropion hydrochloride (JAN/USP); Wellbutrin (TN); Zyban (TN) |
D00818 | Maprotiline hydrochloride (JP16/USP); Ludiomil (TN) |
D00819 | Nefazodone hydrochloride (USAN); Serzone (TN) |
D00820 | Trazodone hydrochloride (JAN/USP); Desyrel (TN) |
D00821 | Venlafaxine hydrochloride (JAN/USAN); Effexor (TN) |
D00822 | Citalopram hydrobromide (USAN); Celexa (TN) |
D00823 | Fluoxetine hydrochloride (JAN/USP); Prozac (TN) |
D00824 | Fluvoxamine maleate (JP16/USAN); Luvox (TN) |
D00825 | Sertraline hydrochloride (JAN/USAN); Zoloft (TN) |
D00847 | Oxycodone hydrochloride (USP); Oxecta (TN); Oxycontin (TN); Roxicodone (TN) |
D00848 | Dextromethorphan hydrobromide hydrate (JP16); Dextromethorphan hydrobromide (USP); Benylin DM (TN) |
D00895 | Delavirdine mesilate (JAN); Delavirdine mesylate (USAN); Rescriptor (TN) |
D00899 | Nelfinavir mesilate (JAN); Nelfinavir mesylate (USAN/INN); Viracept (TN) |
D00966 | Tamoxifen citrate (JP16/USP); Nolvadex (TN) |
D01028 | Ticlopidine hydrochloride (JP16/USAN); Ticlid (TN) |
D01041 | Sparteine (INN) |
D01078 | Telithromycin (JAN/USAN/INN); TEL; Ketek (TN) |
D01096 | Hydroxyzine pamoate (JP16/USP); Atarax-P (TN); Vistaril pamoate (TN) |
D01148 | Tolterodine tartrate (JAN/USAN); Detrol (TN); Detrusitol (TN) |
D01164 | Aripiprazole (JAN/USAN/INN); Abilify (TN) |
D01179 | Duloxetine hydrochloride (JAN/USAN); Cymbalta (TN) |
D01182 | Alprenolol hydrochloride (JP16/USAN); Regletin (TN) |
D01206 | Febuxostat (JAN/USAN/INN); Uloric (TN); Feburic (TN) |
D01242 | Promethazine teoclate (JAN/INN); Avomine (TN) |
D01253 | Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
D01275 | Doxorubicin hydrochloride (JP16/USP); Adriacin (TN); Adriamycin (TN); Doxil (TN); Rubex (TN) |
D01295 | Cinnarizine (JAN/USAN/INN) |
D01302 | Hydralazine hydrochloride (JP16/USP); Apresoline (TN) |
D01303 | Flunarizine hydrochloride (JAN/USAN) |
D01307 | Midodrine hydrochloride (JAN/USAN); Pro-Amatine (TN) |
D01324 | Mequitazine (JP16/INN); Kitazemin (TN) |
D01355 | Tramadol hydrochloride (JAN/USAN); Ultram (TN) |
D01358 | Mianserin hydrochloride (JAN/USAN); Tetramide (TN) |
D01425 | Lopinavir (JAN/USAN/INN) |
D01441 | Imatinib mesilate (JAN); Imatinib mesylate (USAN); Gleevec (TN); Glivec (TN) |
D01444 | Bunitrolol hydrochloride (JAN); Betrilol (TN) |
D01455 | Cibenzoline succinate (JP16); Cifenline succinate (USAN); Cibenol (TN); Cipralan (TN) |
D01481 | Dihydrocodeine phosphate (JP16); Dihydro (TN) |
D01520 | Levomepromazine hydrochloride (JAN/USAN); Nozinan (TN) |
D01546 | Dosulepin hydrochloride (JAN); Dothiepin hydrochloride (USAN); Dosulepin (TN) |
D01624 | Sarpogrelate hydrochloride (JP16); Anplag (TN) |
D01794 | Bopindolol malonate (JAN); Sandonorm (TN) |
D01832 | Modafinil (JAN/USAN/INN); Provigil (TN) |
D01896 | Cilostazol (JP16/USAN/INN); Pletal (TN) |
D01898 | Haloperidol decanoate (JAN/USAN); Halomonth (TN) |
D01929 | Tiotropium bromide hydrate (JAN); Tiotropium bromide monohydrate; Spiriva (TN) |
D01977 | Gefitinib (JAN/USAN/INN); Iressa (TN) |
D01992 | Tandospirone citrate (JAN/USAN); SM 3997; Sediel (TN) |
D02008 | Tadalafil (JAN/USAN/INN); Adcirca (TN); Cialis (TN) |
D02016 | Ramosetron hydrochloride (JAN); YM 060; Nasea (TN) |
D02037 | Perphenazine maleate (JP16); PZC (TN) |
D02074 | Amphetamine sulfate (USP); Benzedrine (TN) |
D02078 | Dextroamphetamine sulfate (USP); Dexedrine (TN); Dextrostat (TN) |
D02086 | Lidocaine injection (JP16); Lidocaine hydrochloride (JAN/USP); Dalcaine (TN); Xylocaine (TN) |
D02091 | Tripelennamine hydrochloride (USP); PBZ-SR (TN) |
D02101 | Codeine phosphate hydrate (JP16); Codeine phosphate (USP); Codeine (TN) |
D02102 | Methadone hydrochloride (JAN/USP); Dolophine hydrochloride (TN) |
D02114 | Hydroxychloroquine sulfate (USP); Plaquenil (TN) |
D02173 | Galantamine hydrobromide (JAN/USAN); Razadyne (TN); Reminyl (TN) |
D02182 | Cocaine hydrochloride (JP16/USP); Cocaine hydrochloride (TN) |
D02213 | Metoclopramide hydrochloride (JAN); Metoclopramide dihydrochloride monohydrate; Primperan (TN); Regl |
D02219 | Terbinafine hydrochloride (JP16/USP); Lamisil (TN) |
D02239 | Sparteine sulfate (JAN/USAN); Sparteine sulfate pentahydrate |
D02248 | Levomepromazine maleate (JP16/USAN); Hirnamin (TN) |
D02260 | Paroxetine hydrochloride hydrate (JAN); Paxil (TN) |
D02272 | Quinidine sulfate hydrate (JP16); Quinidine sulfate (USP); Quinidex (TN) |
D02356 | Verapamil (USAN/INN) |
D02358 | Metoprolol (USAN/INN) |
D02360 | Sertraline (INN) |
D02362 | Paroxetine (USP/INN); Paroxetine (TN) |
D02375 | Terbinafine (USAN/INN); Lamasil (TN) |
D02408 | Trimipramine maleate (JAN/USAN); Surmontil (TN) |
D02485 | Halofantrine hydrochloride (USAN); Halfan (TN) |
D02497 | Fosamprenavir (INN) |
D02561 | Moclobemide (USAN/INN); Aurorix (TN) |
D02566 | Maprotiline (USAN) |
D02567 | Escitalopram oxalate (JAN/USAN); Lexapro (TN) |
D02570 | Desvenlafaxine succinate hydrate (JAN); Desvenlafaxine succinate (USAN); Pristiq (TN) |
D02574 | Atomoxetine hydrochloride (JAN/USAN); Tomoxetine hydrochloride; Strattera (TN) |
D02666 | Iloperidone (USAN/INN); Fanapt (TN) |
D02867 | Fosamprenavir calcium hydrate (JAN); Lexiva (TN) |
D02910 | Amiodarone (USAN/INN) |
D02969 | Aprindine (USAN/INN) |
D03274 | Chlorpromazine hibenzate (JAN); Contomin (TN) |
D03290 | Promethazine methylenedisalicylate (JAN); Pyrethia (TN) |
D03360 | Diphenhydramine laurylsulfate (JAN); Vena (TN) |
D03415 | Carvedilol phosphate hydrate (JAN); Carvedilol phosphate (USAN); Coreg CR (TN) |
D03491 | Cidoxepin hydrochloride (USAN) |
D03492 | Cifenline (USAN); Cibenzoline (INN) |
D03503 | Cimetidine hydrochloride (USP); Cimetidine hydrochloride (TN) |
D03504 | Cinacalcet (USAN) |
D03505 | Cinacalcet hydrochloride (JAN/USAN); Sensipar (TN) |
D03535 | Clemastine (USAN) |
D03556 | Zuclopenthixol (INN); Clopixol (TN) |
D03580 | Codeine sulfate (USP); Codeine sulfate trihydrate |
D03664 | Debrisoquin sulfate (USAN); Declinax (TN) |
D03693 | Desloratadine (USAN/INN); Clarinex (TN) |
D03713 | Dexfenfluramine hydrochloride (USAN); d-Fenfluramine hydrochloride; Redux (TN) |
D03729 | Dexpropranolol hydrochloride (USAN) |
D03731 | Selegiline (USAN/INN); Emsam (TN) |
D03740 | Dextroamphetamine (USAN); Dexamfetamine (INN) |
D03742 | Dextromethorphan (USP) |
D03783 | Oxycodone terephthalate (USP) |
D03830 | Diltiazem malate (USAN); Tiamate (TN) |
D03835 | Fosamprenavir calcium (USAN); Lexiva (TN) |
D03837 | Fosamprenavir sodium (USAN) |
D03854 | Diphenhydramine citrate (USP) |
D03899 | Doxorubicin (USAN/INN); ADR; Adriblastina (TN) |
D03991 | Encainide hydrochloride (USAN) |
D04038 | Perphenazine fendizoate (JAN); PZC (TN) |
D04292 | Galantamine (USAN/INN); Reminyl (TN) |
D04340 | Dextromethorphan hydrobromide - potassium cresolsulfonate mixt; Medicon (TN) |
D04458 | Hydralazine polistirex (USAN) |
D04965 | Perphenazine hydrochloride; Perphenazine dihydrochloride; PZC intramuscular injection (TN) |
D05008 | Metoclopramide hydrochloride (USAN); Metoclopramide hydrochloride monohydrate; Clopra (TN); Reglan ( |
D05011 | Metoprolol fumarate (USP); Lopressor (TN) |
D05024 | Mibefradil dihydrochloride (USAN); Posicor (TN) |
D05039 | Minaprine (USAN/INN); Cantor (TN) |
D05040 | Minaprine hydrochloride (USAN) |
D05127 | Nebivolol (USAN/INN) |
D05312 | Oxycodone (USAN/INN) |
D05343 | Palonocetron hydrochloride (JAN); Palonosetron hydrochloride (USAN); Aloxi (TN) |
D05374 | Paroxetine hydrochloride (USP); Paxil (TN) |
D05375 | Paroxetine mesylate (USAN); Brisdelle (TN); Pexeva (TN) |
D05380 | Pazopanib hydrochloride (JAN/USAN); Votrient (TN) |
D05442 | Perhexiline maleate (USAN) |
D05462 | Oxycodone hydrochloride hydrate (JP16) |
D05649 | Pseudoephedrine sulfate (USP); Afrinol (TN) |
D05699 | Ranitidine bismuth citrate (USAN); Tritec (TN) |
D05928 | Stiripentol (JAN/USAN/INN) |
D06246 | Tripelennamine citrate; PBZ (TN) |
D06542 | Ethanol (JP16); Ethanol (TN) |
D06622 | Nebivolol hydrochloride (USAN); Bystolic (TN) |
D06623 | Olanzapine pamoate (USAN); Olanzapine pamoate monohydrate |
D07156 | Alprenolol (INN) |
D07175 | Palonosetron (INN); Aloxi (TN) |
D07448 | Amitriptyline (INN); Laroxyl (TN) |
D07473 | Atomoxetine (INN); Tomoxetine |
D07520 | Bepridil (INN); Bepadin (TN) |
D07591 | Bupropion (INN) |
D07624 | Carteolol (INN) |
D07667 | Cevimeline (INN) |
D07704 | Citalopram (USP/INN); Citadur (TN) |
D07705 | Citalopram hydrochloride; Seropram (TN) |
D07727 | Clomipramine (INN); Anafranil (TN) |
D07734 | Cinnarizine dihydrochloride; Celenid (TN) |
D07740 | Codeine hydrochloride; Bisoltus (TN) |
D07782 | Delavirdine (INN) |
D07791 | Desipramine (INN) |
D07793 | Desvenlafaxine (INN) |
D07803 | Dexchlorpheniramine (INN); d-Chloropheniramine; Dapriton (TN) |
D07805 | Dexfenfluramine (INN) |
D07831 | Dihydrocodeine (INN); Remedacen (TN) |
D07845 | Diltiazem (INN); Surazem (TN) |
D07869 | Donepezil (INN); Donaz (TN) |
D07875 | Doxepin (INN); Sinequan (TN) |
D07880 | Duloxetine (INN); Yentreve (TN) |
D07894 | Encainide (INN) |
D07913 | Escitalopram (INN); Esertia (TN) |
D07938 | Bupropion hydrobromide (USAN) |
D07962 | Flecainide (INN) |
D07971 | Flunarizine (INN); Sibelium (TN) |
D07977 | Fluphenazine (INN); Moditen (TN) |
D07984 | Fluvoxamine (INN) |
D08033 | Halofantrine (INN) |
D08044 | Hydralazine (INN); Hidral (TN) |
D08050 | Hydroxychloroquine (INN); Polirreumin (TN) |
D08054 | Hydroxyzine (INN); Marex (TN) |
D08066 | Imatinib (INN); Glamox (TN) |
D08070 | Imipramine (INN); Tofranil (TN) |
D08071 | Imipramine embonate; Tofranil-pm (TN) |
D08121 | Levomethadone (INN) |
D08122 | Levomethadone hydrochloride; L-polamidon (TN) |
D08127 | Lidocaine hydrochloride monohydrate; Lidocaine (TN) |
D08195 | Methadone (BAN) |
D08215 | Mexiletine (INN) |
D08216 | Mianserin (INN); Tolvon (TN) |
D08217 | Mibefradil (INN) |
D08220 | Midodrine (INN) |
D08255 | Naratriptan (INN); Naramig (TN) |
D08257 | Nefazodone (INN) |
D08259 | Nelfinavir (INN); Viracept (TN) |
D08288 | Nortriptyline (INN); Nortrilen (TN) |
D08339 | Pergolide (INN); Permax (TN) |
D08340 | Perhexiline (INN) |
D08351 | Phenformin (BAN) |
D08352 | Phenformin hydrochloride; Debei (TN) |
D08432 | Promethazine maleate; Romergan (TN) |
D08435 | Propafenone (INN); Propafenon hexal (TN) |
D08443 | Propranolol (INN); Propranolol (TN) |
D08447 | Protriptyline (INN) |
D08449 | Pseudoephedrine (INN); Neodurasina (TN); Acunaso (TN) |
D08458 | Quinidine (BAN); Kinidin (TN) |
D08459 | Quinidine phenylethylbarbiturate; Quinidine 5-ethyl 5-phenyl barbiturate; Natisedine (TN) |
D08466 | Ramosetron (INN) |
D08479 | Rifampicin sodium; Rifadine (TN) |
D08508 | Sarpogrelate (INN) |
D08559 | Tamoxifen (INN); Tamoxifen (TN); Tamoplex (TN) |
D08561 | Tandospirone (INN) |
D08575 | Tetrabenazine (JAN/INN); Nitoman (TN); Xenazine (TN) |
D08594 | Ticlopidine (INN); Ticlopidin-Puren (TN) |
D08600 | Timolol (INN); Timolol (TN); Betimol (TN) |
D08623 | Tramadol (INN); Amanda (TN) |
D08626 | Trazodone (INN); Trittico (TN) |
D08645 | Tripelennamine (INN) |
D08670 | Venlafaxine (INN); Efectin (TN) |
D08693 | Zuclopenthixol dihydrochloride; Clopixol (TN) |
D08768 | Promethazine hibenzate; Hiberna (TN) |
D09999 | Tramadol hydrochloride - acetaminophen mixt; Tramcet (TN) |
D10206 | Olanzapine - fluoxetine hydrochloride mixt; Symbyax (TN) |
D10207 | Chlordiazepoxide and amitriptyline hydrochloride; Chlordiazepoxide and amitriptyline hcl (TN) |
D10208 | Dextromethorphan hydrobromide and quinidine sulfate; Nuedexta (TN) |
DrugBank | |
DB05812 | Abiraterone |
DB01193 | Acebutolol |
DB00316 | Acetaminophen |
DB01426 | Ajmaline |
DB00918 | Almotriptan |
DB06203 | Alogliptin |
DB00866 | Alprenolol |
DB01424 | Aminophenazone |
DB01118 | Amiodarone |
DB00321 | Amitriptyline |
DB00381 | Amlodipine |
DB00613 | Amodiaquine |
DB00543 | Amoxapine |
DB00182 | Amphetamine |
DB00701 | Amprenavir |
DB00276 | Amsacrine |
DB01435 | Antipyrine |
DB01429 | Aprindine |
DB01274 | Arformoterol |
DB01238 | Aripiprazole |
DB06697 | Artemether |
DB06216 | Asenapine |
DB00637 | Astemizole |
DB00289 | Atomoxetine |
DB01076 | Atorvastatin |
DB00972 | Azelastine |
DB00245 | Benzatropine |
DB06770 | Benzyl alcohol |
DB01244 | Bepridil |
DB00195 | Betaxolol |
DB01128 | Bicalutamide |
DB00810 | Biperiden |
DB00612 | Bisoprolol |
DB00188 | Bortezomib |
DB00835 | Brompheniramine |
DB00297 | Bupivacaine |
DB00921 | Buprenorphine |
DB01156 | Bupropion |
DB00490 | Buspirone |
DB00201 | Caffeine |
DB01197 | Captopril |
DB00748 | Carbinoxamine |
DB00521 | Carteolol |
DB01136 | Carvedilol |
DB00482 | Celecoxib |
DB00567 | Cephalexin |
DB00185 | Cevimeline |
DB00475 | Chlordiazepoxide |
DB00608 | Chloroquine |
DB01114 | Chlorphenamine |
DB00477 | Chlorpromazine |
DB00356 | Chlorzoxazone |
DB00169 | Cholecalciferol |
DB01410 | Ciclesonide |
DB01166 | Cilostazol |
DB00501 | Cimetidine |
DB01012 | Cinacalcet |
DB00568 | Cinnarizine |
DB00604 | Cisapride |
DB00215 | Citalopram |
DB00283 | Clemastine |
DB04920 | Clevidipine |
DB01242 | Clomipramine |
DB00575 | Clonidine |
DB00257 | Clotrimazole |
DB00363 | Clozapine |
DB00907 | Cocaine |
DB00318 | Codeine |
DB00924 | Cyclobenzaprine |
DB00531 | Cyclophosphamide |
DB00091 | Cyclosporine |
DB06292 | Dapagliflozin |
DB00496 | Darifenacin |
DB04840 | Debrisoquin |
DB00705 | Delavirdine |
DB01151 | Desipramine |
DB00967 | Desloratadine |
DB01234 | Dexamethasone |
DB01191 | Dexfenfluramine |
DB00633 | Dexmedetomidine |
DB06701 | Dexmethylphenidate |
DB01576 | Dextroamphetamine |
DB00514 | Dextromethorphan |
DB00647 | Dextropropoxyphene |
DB01551 | Dihydrocodeine |
DB00343 | Diltiazem |
DB01093 | Dimethyl sulfoxide |
DB01075 | Diphenhydramine |
DB00757 | Dolasetron |
DB01184 | Domperidone |
DB00843 | Donepezil |
DB00988 | Dopamine |
DB00590 | Doxazosin |
DB01142 | Doxepin |
DB00997 | Doxorubicin |
DB04855 | Dronedarone |
DB00476 | Duloxetine |
DB00625 | Efavirenz |
DB00216 | Eletriptan |
DB01228 | Encainide |
DB08899 | Enzalutamide |
DB00751 | Epinastine |
DB00530 | Erlotinib |
DB01175 | Escitalopram |
DB01466 | Ethylmorphine |
DB01628 | Etoricoxib |
DB01023 | Felodipine |
DB06702 | Fesoterodine |
DB00950 | Fexofenadine |
DB08868 | Fingolimod |
DB01195 | Flecainide |
DB04841 | Flunarizine |
DB00472 | Fluoxetine |
DB00623 | Fluphenazine |
DB01095 | Fluvastatin |
DB00176 | Fluvoxamine |
DB00983 | Formoterol |
DB00674 | Galantamine |
DB00317 | Gefitinib |
DB01437 | Glutethimide |
DB00889 | Granisetron |
DB01218 | Halofantrine |
DB00502 | Haloperidol |
DB01159 | Halothane |
DB00667 | Histamine Phosphate |
DB00956 | Hydrocodone |
DB00327 | Hydromorphone |
DB01611 | Hydroxychloroquine |
DB01005 | Hydroxyurea |
DB00557 | Hydroxyzine |
DB01177 | Idarubicin |
DB04946 | Iloperidone |
DB00619 | Imatinib |
DB00458 | Imipramine |
DB00224 | Indinavir |
DB00332 | Ipratropium bromide |
DB01029 | Irbesartan |
DB00951 | Isoniazid |
DB01167 | Itraconazole |
DB01026 | Ketoconazole |
DB01235 | L-DOPA |
DB00598 | Labetalol |
DB00448 | Lansoprazole |
DB00528 | Lercanidipine |
DB08918 | Levomilnacipran |
DB00281 | Lidocaine |
DB00589 | Lisuride |
DB01206 | Lomustine |
DB00836 | Loperamide |
DB01601 | Lopinavir |
DB00455 | Loratadine |
DB04871 | Lorcaserin |
DB00227 | Lovastatin |
DB06708 | Lumefantrine |
DB00934 | Maprotiline |
DB00358 | Mefloquine |
DB06691 | Mepyramine |
DB01071 | Mequitazine |
DB00933 | Mesoridazine |
DB00333 | Methadone |
DB01577 | Methamphetamine |
DB00703 | Methazolamide |
DB00763 | Methimazole |
DB01403 | Methotrimeprazine |
DB01028 | Methoxyflurane |
DB06800 | Methylnaltrexone |
DB00422 | Methylphenidate |
DB01107 | Methyprylon |
DB01233 | Metoclopramide |
DB00264 | Metoprolol |
DB00379 | Mexiletine |
DB06148 | Mianserin |
DB01110 | Miconazole |
DB00211 | Midodrine |
DB00834 | Mifepristone |
DB00805 | Minaprine |
DB08893 | Mirabegron |
DB00370 | Mirtazapine |
DB01171 | Moclobemide |
DB00295 | Morphine |
DB00731 | Nateglinide |
DB04861 | Nebivolol |
DB01149 | Nefazodone |
DB00220 | Nelfinavir |
DB00238 | Nevirapine |
DB00627 | Niacin |
DB00622 | Nicardipine |
DB00699 | Nicergoline |
DB00184 | Nicotine |
DB01115 | Nifedipine |
DB04868 | Nilotinib |
DB00336 | Nitrofural |
DB00540 | Nortriptyline |
DB00334 | Olanzapine |
DB00338 | Omeprazole |
DB00904 | Ondansetron |
DB01096 | Oxamniquine |
DB01580 | Oxprenolol |
DB01062 | Oxybutynin |
DB00497 | Oxycodone |
DB01192 | Oxymorphone |
DB01267 | Paliperidone |
DB00377 | Palonosetron |
DB00715 | Paroxetine |
DB06589 | Pazopanib |
DB00738 | Pentamidine |
DB01186 | Pergolide |
DB01074 | Perhexiline |
DB00850 | Perphenazine |
DB00454 | Pethidine |
DB00914 | Phenformin |
DB00191 | Phentermine |
DB01100 | Pimozide |
DB00960 | Pindolol |
DB01132 | Pioglitazone |
DB00592 | Piperazine |
DB01621 | Pipotiazine |
DB08901 | Ponatinib |
DB00175 | Pravastatin |
DB01058 | Praziquantel |
DB01087 | Primaquine |
DB01035 | Procainamide |
DB00433 | Prochlorperazine |
DB00396 | Progesterone |
DB01131 | Proguanil |
DB01069 | Promethazine |
DB01182 | Propafenone |
DB00818 | Propofol |
DB00571 | Propranolol |
DB00344 | Protriptyline |
DB00852 | Pseudoephedrine |
DB00205 | Pyrimethamine |
DB01224 | Quetiapine |
DB00908 | Quinidine |
DB00468 | Quinine |
DB01129 | Rabeprazole |
DB00863 | Ranitidine |
DB00243 | Ranolazine |
DB00234 | Reboxetine |
DB00409 | Remoxipride |
DB01201 | Rifapentine |
DB00734 | Risperidone |
DB00503 | Ritonavir |
DB00989 | Rivastigmine |
DB00268 | Ropinirole |
DB00296 | Ropivacaine |
DB00412 | Rosiglitazone |
DB05271 | Rotigotine |
DB01232 | Saquinavir |
DB01037 | Selegiline |
DB06144 | Sertindole |
DB01104 | Sertraline |
DB00203 | Sildenafil |
DB00641 | Simvastatin |
DB00398 | Sorafenib |
DB00259 | Sulfanilamide |
DB06729 | Sulfaphenazole |
DB00675 | Tamoxifen |
DB00706 | Tamsulosin |
DB06204 | Tapentadol |
DB00976 | Telithromycin |
DB06287 | Temsirolimus |
DB00857 | Terbinafine |
DB04844 | Tetrabenazine |
DB00277 | Theophylline |
DB00679 | Thioridazine |
DB01623 | Thiothixene |
DB00208 | Ticlopidine |
DB00373 | Timolol |
DB01409 | Tiotropium |
DB00932 | Tipranavir |
DB01036 | Tolterodine |
DB05109 | Trabectedin |
DB00193 | Tramadol |
DB00752 | Tranylcypromine |
DB00656 | Trazodone |
DB00726 | Trimipramine |
DB00792 | Tripelennamine |
DB00427 | Triprolidine |
DB00209 | Trospium |
DB08881 | Vemurafenib |
DB00285 | Venlafaxine |
DB00661 | Verapamil |
DB06684 | Vilazodone |
DB00570 | Vinblastine |
DB00361 | Vinorelbine |
DB01392 | Yohimbine |
DB00549 | Zafirlukast |
DB00943 | Zalcitabine |
DB00246 | Ziprasidone |
DB00425 | Zolpidem |
DB01624 | Zuclopenthixol |
loading...