CN093_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CN093_HUMAN
• UniProt AC: Q9H972
• Protein Name: Uncharacterized protein C14orf93
• Gene Name: C14orf93
• Organism: Homo sapiens (Human).
• Sequence Length: 538
• Subcellular Localization: Secreted .
• Protein Sequence: MSFSATILFSPPSGSEARCCCCACKSETNGGNTGSQGGNPPPSTPITVTGHGLAVQSSEQLLHVIYQRVDKAVGLAEAALGLARANNELLKRLQEEVGDLRQGKVSIPDEDGESRAHSSPPEEPGPLKESPGEAFKALSAVEEECDSVGSGVQVVIEELRQLGAASVGPGPLGFPATQRDMRLPGCTLAASEAAPLLNPLVDDYVASEGAVQRVLVPAYAKQLSPATQLAIQRATPETGPENGTKLPPPRPEDMLNAAAALDSALEESGPGSTGELRHSLGLTVSPCRTRGSGQKNSRRKRDLVLSKLVHNVHNHITNDKRFNGSESIKSSWNISVVKFLLEKLKQELVTSPHNYTDKELKGACVAYFLTKRREYRNSLNPFKGLKEKEEKKLRSRRYRLFANRSSIMRHFGPEDQRLWNDVTEELMSDEEDSLNEPGVWVARPPRFRAQRLTELCYHLDANSKHGTKANRVYGPPSDRLPSAEAQLLPPELYNPNFQEEEDEGGDENAPGSPSFDQPHKTCCPDLNSFIEIKVEKDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MSFSATILFSP ----CCCEEEEEECC	19.73	29507054
6	Phosphorylation	--MSFSATILFSPPS --CCCEEEEEECCCC	19.60	29507054
10	Phosphorylation	FSATILFSPPSGSEA CEEEEEECCCCCCCC	32.24	29507054
71 (in isoform 2)	Ubiquitination	-	41.96	21890473
71 (in isoform 1)	Ubiquitination	-	41.96	21890473
71	Ubiquitination	VIYQRVDKAVGLAEA HHHHHHHHHHHHHHH	41.96	21890473
104	Ubiquitination	VGDLRQGKVSIPDED HCCHHCCCCCCCCCC	25.19	-
114	Phosphorylation	IPDEDGESRAHSSPP CCCCCCCCCCCCCCC	40.05	23927012
118	Phosphorylation	DGESRAHSSPPEEPG CCCCCCCCCCCCCCC	43.48	25849741
119	Phosphorylation	GESRAHSSPPEEPGP CCCCCCCCCCCCCCC	34.31	29255136
128	Sumoylation	PEEPGPLKESPGEAF CCCCCCCCCCHHHHH	60.32	28112733
130	Phosphorylation	EPGPLKESPGEAFKA CCCCCCCCHHHHHHH	36.30	29255136
166	Phosphorylation	LRQLGAASVGPGPLG HHHCCCCCCCCCCCC	27.37	28857561
221	Sumoylation	VLVPAYAKQLSPATQ HHHHHHHHHCCHHHH	38.81	28112733
224	Phosphorylation	PAYAKQLSPATQLAI HHHHHHCCHHHHHHH	15.25	25159151
227	Phosphorylation	AKQLSPATQLAIQRA HHHCCHHHHHHHHHC	27.74	28302921
235	Phosphorylation	QLAIQRATPETGPEN HHHHHHCCCCCCCCC	24.68	28985074
238	Phosphorylation	IQRATPETGPENGTK HHHCCCCCCCCCCCC	60.27	27794612
244	Phosphorylation	ETGPENGTKLPPPRP CCCCCCCCCCCCCCH	40.78	27794612
279	Phosphorylation	STGELRHSLGLTVSP CHHHHHHHCCCEEEC	20.07	25159151
283	Phosphorylation	LRHSLGLTVSPCRTR HHHHCCCEEECCCCC	19.69	30266825
285	Phosphorylation	HSLGLTVSPCRTRGS HHCCCEEECCCCCCC	17.04	23401153
320	Ubiquitination	HNHITNDKRFNGSES HHHHCCCCCCCCCCC	62.04	-
367	Phosphorylation	LKGACVAYFLTKRRE HHHHHHHHHHHCCHH	4.44	-
370	Phosphorylation	ACVAYFLTKRREYRN HHHHHHHHCCHHHHH	16.77	-
423	Phosphorylation	QRLWNDVTEELMSDE HHHHHHHHHHHHCCC	26.97	22115753
428 (in isoform 2)	Phosphorylation	-	55.27	24260401
428	Phosphorylation	DVTEELMSDEEDSLN HHHHHHHCCCCCCCC	55.27	29507054
463	Phosphorylation	CYHLDANSKHGTKAN HHHCCCCCCCCCCCC	27.96	22985185
493	Phosphorylation	QLLPPELYNPNFQEE HHCCHHHCCCCCCCC	27.23	30108239
512	Phosphorylation	GDENAPGSPSFDQPH CCCCCCCCCCCCCCC	19.13	30108239
514	Phosphorylation	ENAPGSPSFDQPHKT CCCCCCCCCCCCCCC	43.05	27251275
533	Sumoylation	LNSFIEIKVEKDE-- CHHHEEEEEECCC--	31.39	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CN093_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CN093_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CN093_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
MOFA1_HUMAN	MRFAP1	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.