MOFA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MOFA1_HUMAN
• UniProt AC: Q9Y605
• Protein Name: MORF4 family-associated protein 1
• Gene Name: MRFAP1 {ECO:0000312|EMBL:AAH22797.1}
• Organism: Homo sapiens (Human).
• Sequence Length: 127
• Subcellular Localization: Nucleus . Cytoplasm, perinuclear region . Colocalizes with MORF4L1 to cell nuclei.
• Protein Sequence: MRPLDIVELAEPEEVEVLEPEEDFEQFLLPVINEMREDIASLTREHGRAYLRNRSKLWEMDNMLIQIKTQVEASEESALNHLQNPGDAAEGRAAKRCEKAEEKAKEIAKMAEMLVELVRRIEKSESS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Phosphorylation	EMREDIASLTREHGR HHHHHHHHHHHHHHH	30.52	21815630
55	Phosphorylation	RAYLRNRSKLWEMDN HHHHHCHHHHHHHHH	35.33	-
56	Ubiquitination	AYLRNRSKLWEMDNM HHHHCHHHHHHHHHH	55.15	21890473
68	Ubiquitination	DNMLIQIKTQVEASE HHHHHHHHHHHHCCH	19.27	-
74	Phosphorylation	IKTQVEASEESALNH HHHHHHCCHHHHHHH	28.52	29214152
77	Phosphorylation	QVEASEESALNHLQN HHHCCHHHHHHHCCC	33.72	28555341
95	Ubiquitination	AAEGRAAKRCEKAEE HHHHHHHHHHHHHHH	57.50	-
109	Ubiquitination	EKAKEIAKMAEMLVE HHHHHHHHHHHHHHH	44.28	2063986
123	Ubiquitination	ELVRRIEKSESS--- HHHHHHHHHCCC---	58.09	21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MOFA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MOFA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MOFA1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MO4L1_HUMAN	MORF4L1	physical	11500496
RB_HUMAN	RB1	physical	11500496
RB_HUMAN	RB1	physical	12397079
MO4L1_HUMAN	MORF4L1	physical	12397079
MO4L1_HUMAN	MORF4L1	physical	17008723
MO4L1_MOUSE	Morf4l1	physical	15367658
SUV92_HUMAN	SUV39H2	physical	23455924
MR1L1_HUMAN	MRFAP1L1	physical	25416956
CC062_HUMAN	C3orf62	physical	25416956
MO4L2_HUMAN	MORF4L2	physical	21516116

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.