dbPTM

CLAP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CLAP1_HUMAN
UniProt AC	Q7Z460
Protein Name	CLIP-associating protein 1
Gene Name	CLASP1
Organism	Homo sapiens (Human).
Sequence Length	1538
Subcellular Localization	Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Golgi apparatus, trans-Golgi network . Localizes to microtubule plus ends. Localizes t
Protein Description	Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle..
Protein Sequence	MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLAKHPPPFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	VGQELIDYFSDKQKS HHHHHHHHHCHHHHC	9.66	29396449
32	Phosphorylation	QELIDYFSDKQKSAD HHHHHHHCHHHHCCC	37.35	29396449
91	Phosphorylation	RFKAQIGTVLPSLID HHHHHHHCHHHHHHH	22.09	21406692
95	Phosphorylation	QIGTVLPSLIDRLGD HHHCHHHHHHHHHCC	33.52	21406692
214	Phosphorylation	SKKGLPQSRLNVIFT HHCCCCHHHHEEEEE	36.47	20860994
228	Ubiquitination	TKFDEVQKSGNMIQS ECHHHHHHHCCCCCC	66.56	-
228	Ubiquitination	TKFDEVQKSGNMIQS ECHHHHHHHCCCCCC	66.56	21906983
228	Ubiquitination	TKFDEVQKSGNMIQS ECHHHHHHHCCCCCC	66.56	22817900
228 (in isoform 1)	Ubiquitination	-	66.56	21890473
228 (in isoform 2)	Ubiquitination	-	66.56	21890473
228 (in isoform 3)	Ubiquitination	-	66.56	21890473
246	Phosphorylation	KNFDDEDSVDGNRPS CCCCCCCCCCCCCCC	21.76	25159151
253	Phosphorylation	SVDGNRPSSASSTSS CCCCCCCCCCCCCCC	34.99	28450419
254	Phosphorylation	VDGNRPSSASSTSSK CCCCCCCCCCCCCCC	34.55	25159151
256	Phosphorylation	GNRPSSASSTSSKAP CCCCCCCCCCCCCCC	35.78	28450419
257	Phosphorylation	NRPSSASSTSSKAPP CCCCCCCCCCCCCCC	31.83	23663014
258	Phosphorylation	RPSSASSTSSKAPPS CCCCCCCCCCCCCCH	34.23	23663014
259	Phosphorylation	PSSASSTSSKAPPSS CCCCCCCCCCCCCHH	31.61	28450419
260	Phosphorylation	SSASSTSSKAPPSSR CCCCCCCCCCCCHHH	32.69	28450419
274	Phosphorylation	RRNVGMGTTRRLGSS HCCCCCCCCCCCCCC	14.29	-
275	Phosphorylation	RNVGMGTTRRLGSST CCCCCCCCCCCCCCC	14.20	21601212
280	Phosphorylation	GTTRRLGSSTLGSKS CCCCCCCCCCCCCCH	25.41	27134283
281	Phosphorylation	TTRRLGSSTLGSKSS CCCCCCCCCCCCCHH	26.34	28450419
282	Phosphorylation	TRRLGSSTLGSKSSA CCCCCCCCCCCCHHH	36.51	28450419
285	Phosphorylation	LGSSTLGSKSSAAKE CCCCCCCCCHHHHHC	32.26	26434776
304	Ubiquitination	VDEEDFIKAFDDVPV CCHHHHHHHCCCCCE	42.89	29967540
326	Ubiquitination	DLEESINKIREILSD CHHHHHHHHHHHHHC	41.28	29967540
335	Ubiquitination	REILSDDKHDWEQRV HHHHHCCCCCHHHHH	48.75	29967540
425	Sulfoxidation	IPNSAKIMATSGVVA CCCCCHHHHHCCCHH	3.07	21406390
428	Phosphorylation	SAKIMATSGVVAVRL CCHHHHHCCCHHHHH	21.76	21601212
453	Ubiquitination	IPVITSNCTSKSVAV HHEECCCCCCCCHHH	4.56	24816145
484	Ubiquitination	THSLERHISVLAETI HHHHHHHHHHHHHHH	3.69	24816145
485	Phosphorylation	HSLERHISVLAETIK HHHHHHHHHHHHHHH	12.64	23312004
485	Ubiquitination	HSLERHISVLAETIK HHHHHHHHHHHHHHH	12.64	24816145
491	Ubiquitination	ISVLAETIKKGIHDA HHHHHHHHHHCCCCC	3.06	24816145
492	Ubiquitination	SVLAETIKKGIHDAD HHHHHHHHHCCCCCC	52.98	24816145
493	Ubiquitination	VLAETIKKGIHDADS HHHHHHHHCCCCCCH	60.28	-
493	Ubiquitination	VLAETIKKGIHDADS HHHHHHHHCCCCCCH	60.28	-
508	Ubiquitination	EARIEARKCYWGFHS HHHHHHHHCCCCCHH	38.43	24816145
543	Phosphorylation	LQSHLKNSDSIVSLP HHHHHCCCCCCCCCC	31.02	20071362
545	Phosphorylation	SHLKNSDSIVSLPQS HHHCCCCCCCCCCCC	25.39	23927012
548	Phosphorylation	KNSDSIVSLPQSDRS CCCCCCCCCCCCCCC	32.44	20363803
552	Phosphorylation	SIVSLPQSDRSSSSS CCCCCCCCCCCCCCC	32.81	25159151
555	Phosphorylation	SLPQSDRSSSSSQES CCCCCCCCCCCCHHH	39.29	30266825
556	Phosphorylation	LPQSDRSSSSSQESL CCCCCCCCCCCHHHH	34.82	30266825
557	Phosphorylation	PQSDRSSSSSQESLN CCCCCCCCCCHHHHC	34.94	30266825
558	Phosphorylation	QSDRSSSSSQESLNR CCCCCCCCCHHHHCC	37.68	23401153
559	Phosphorylation	SDRSSSSSQESLNRP CCCCCCCCHHHHCCC	39.66	25159151
562	Phosphorylation	SSSSSQESLNRPLSA CCCCCHHHHCCCCCC	24.25	30266825
568	Phosphorylation	ESLNRPLSAKRSPTG HHHCCCCCCCCCCCC	34.13	17525332
570	Acetylation	LNRPLSAKRSPTGST HCCCCCCCCCCCCCC	50.46	25953088
572	Phosphorylation	RPLSAKRSPTGSTTS CCCCCCCCCCCCCCC	26.55	27461979
574	Phosphorylation	LSAKRSPTGSTTSRA CCCCCCCCCCCCCCC	45.04	27461979
576	Phosphorylation	AKRSPTGSTTSRAST CCCCCCCCCCCCCCC	30.87	23403867
577	Phosphorylation	KRSPTGSTTSRASTV CCCCCCCCCCCCCCE	30.09	23403867
578	Phosphorylation	RSPTGSTTSRASTVS CCCCCCCCCCCCCEE	20.22	23403867
579	O-linked_Glycosylation	SPTGSTTSRASTVST CCCCCCCCCCCCEEC	26.41	30379171
579	Phosphorylation	SPTGSTTSRASTVST CCCCCCCCCCCCEEC	26.41	23403867
582	Ubiquitination	GSTTSRASTVSTKSV CCCCCCCCCEECCCC	28.38	21890473
586	Phosphorylation	SRASTVSTKSVSTTG CCCCCEECCCCCCCC	24.01	-
588	O-linked_Glycosylation	ASTVSTKSVSTTGSL CCCEECCCCCCCCCC	22.76	30379171
588	Phosphorylation	ASTVSTKSVSTTGSL CCCEECCCCCCCCCC	22.76	25159151
590	Phosphorylation	TVSTKSVSTTGSLQR CEECCCCCCCCCCCC	27.61	25159151
591	Phosphorylation	VSTKSVSTTGSLQRS EECCCCCCCCCCCCC	32.78	21955146
592	Phosphorylation	STKSVSTTGSLQRSR ECCCCCCCCCCCCCC	19.78	21955146
594	Phosphorylation	KSVSTTGSLQRSRSD CCCCCCCCCCCCCCC	21.16	25159151
598	Phosphorylation	TTGSLQRSRSDIDVN CCCCCCCCCCCCCHH	24.15	22167270
600	Phosphorylation	GSLQRSRSDIDVNAA CCCCCCCCCCCHHHH	39.92	29255136
600 (in isoform 3)	Phosphorylation	-	39.92	18669648
605	Ubiquitination	SRSDIDVNAAASAKS CCCCCCHHHHHHHHC	21.80	21890473
606	Ubiquitination	RSDIDVNAAASAKSK CCCCCHHHHHHHHCH	12.31	21890473
609	Phosphorylation	IDVNAAASAKSKVSS CCHHHHHHHHCHHCC	31.35	23927012
610	Ubiquitination	DVNAAASAKSKVSSS CHHHHHHHHCHHCCC	18.53	21890473
612	Phosphorylation	NAAASAKSKVSSSSG HHHHHHHCHHCCCCC	37.70	-
612	Ubiquitination	NAAASAKSKVSSSSG HHHHHHHCHHCCCCC	37.70	21890473
613	Ubiquitination	AAASAKSKVSSSSGT HHHHHHCHHCCCCCC	45.49	21890473
615	Phosphorylation	ASAKSKVSSSSGTTP HHHHCHHCCCCCCCC	28.39	26074081
618	Ubiquitination	KSKVSSSSGTTPFSS HCHHCCCCCCCCCCC	41.95	21890473
619	Ubiquitination	SKVSSSSGTTPFSSA CHHCCCCCCCCCCCC	35.24	21890473
620	Ubiquitination	KVSSSSGTTPFSSAA HHCCCCCCCCCCCCC	32.99	21890473
621	Ubiquitination	VSSSSGTTPFSSAAA HCCCCCCCCCCCCCC	26.34	21890473
624	Phosphorylation	SSGTTPFSSAAALPP CCCCCCCCCCCCCCC	21.92	26074081
625	Phosphorylation	SGTTPFSSAAALPPG CCCCCCCCCCCCCCC	23.47	28152594
633	Phosphorylation	AAALPPGSYASLGRI CCCCCCCCCHHCCCC	24.25	28555341
633 (in isoform 4)	Phosphorylation	-	24.25	27050516
634	Phosphorylation	AALPPGSYASLGRIR CCCCCCCCHHCCCCE	13.21	30175587
634 (in isoform 4)	Phosphorylation	-	13.21	-
636	Phosphorylation	LPPGSYASLGRIRTR CCCCCCHHCCCCEEE	24.11	22617229
636 (in isoform 4)	Phosphorylation	-	24.11	27050516
639 (in isoform 4)	Phosphorylation	-	22.10	29507054
642	Phosphorylation	ASLGRIRTRRQSSGS HHCCCCEEECCCCCC	28.03	23403867
646	Phosphorylation	RIRTRRQSSGSATNV CCEEECCCCCCCCCC	34.55	29255136
646 (in isoform 3)	Phosphorylation	-	34.55	18669648
647	Phosphorylation	IRTRRQSSGSATNVA CEEECCCCCCCCCCC	28.55	29255136
647 (in isoform 3)	Phosphorylation	-	28.55	18669648
648	Ubiquitination	RTRRQSSGSATNVAS EEECCCCCCCCCCCC	26.92	21890473
648 (in isoform 4)	Phosphorylation	-	26.92	24719451
649	Phosphorylation	TRRQSSGSATNVAST EECCCCCCCCCCCCC	33.59	29255136
649	Ubiquitination	TRRQSSGSATNVAST EECCCCCCCCCCCCC	33.59	21890473
649 (in isoform 3)	Phosphorylation	-	33.59	18669648
651	Phosphorylation	RQSSGSATNVASTPD CCCCCCCCCCCCCCC	31.74	29255136
651 (in isoform 3)	Phosphorylation	-	31.74	18220336
653 (in isoform 4)	Phosphorylation	-	3.75	24719451
654 (in isoform 5)	Phosphorylation	-	15.12	29116813
655	Phosphorylation	GSATNVASTPDNRGR CCCCCCCCCCCCCCC	35.87	29255136
655 (in isoform 5)	Phosphorylation	-	35.87	29116813
656	Phosphorylation	SATNVASTPDNRGRS CCCCCCCCCCCCCCH	25.56	29255136
656 (in isoform 3)	Phosphorylation	-	25.56	18669648
657	Ubiquitination	ATNVASTPDNRGRSR CCCCCCCCCCCCCHH	34.09	21890473
657 (in isoform 5)	Phosphorylation	-	34.09	29116813
660	Methylation	VASTPDNRGRSRAKV CCCCCCCCCCHHHEE	49.64	-
662	Methylation	STPDNRGRSRAKVVS CCCCCCCCHHHEECC	21.52	-
662 (in isoform 4)	Phosphorylation	-	21.52	25849741
663 (in isoform 4)	Phosphorylation	-	39.14	25849741
665 (in isoform 4)	Phosphorylation	-	15.39	25849741
667 (in isoform 4)	Phosphorylation	-	4.96	29507054
671	Phosphorylation	RAKVVSQSQRSRSAN HHEECCHHHHHHCCC	21.76	25367160
673	Ubiquitination	KVVSQSQRSRSANPA EECCHHHHHHCCCCC	39.01	21890473
674	Phosphorylation	VVSQSQRSRSANPAG ECCHHHHHHCCCCCC	23.97	21406692
676	Phosphorylation	SQSQRSRSANPAGAG CHHHHHHCCCCCCCC	33.37	21406692
684	Phosphorylation	ANPAGAGSRSSSPGK CCCCCCCCCCCCCCC	28.58	21406692
685 (in isoform 4)	Phosphorylation	-	39.37	30266825
686	Phosphorylation	PAGAGSRSSSPGKLL CCCCCCCCCCCCCCC	36.54	23927012
686 (in isoform 3)	Phosphorylation	-	36.54	18669648
687	Phosphorylation	AGAGSRSSSPGKLLG CCCCCCCCCCCCCCC	39.17	23927012
687 (in isoform 4)	Phosphorylation	-	39.17	30266825
688	Phosphorylation	GAGSRSSSPGKLLGS CCCCCCCCCCCCCCC	38.63	23401153
688 (in isoform 3)	Phosphorylation	-	38.63	18669648
691	Acetylation	SRSSSPGKLLGSGYG CCCCCCCCCCCCCCC	43.87	25953088
691 (in isoform 4)	Phosphorylation	-	43.87	30266825
693 (in isoform 4)	Phosphorylation	-	6.13	25849741
694 (in isoform 4)	Phosphorylation	-	29.48	25849741
695	Phosphorylation	SPGKLLGSGYGGLTG CCCCCCCCCCCCCCC	28.89	25159151
695 (in isoform 3)	Phosphorylation	-	28.89	18669648
695 (in isoform 4)	Phosphorylation	-	28.89	25159151
697	Phosphorylation	GKLLGSGYGGLTGGS CCCCCCCCCCCCCCC	15.09	23927012
701	Phosphorylation	GSGYGGLTGGSSRGP CCCCCCCCCCCCCCC	42.65	25159151
702 (in isoform 4)	Phosphorylation	-	38.74	23927012
704	Phosphorylation	YGGLTGGSSRGPPVT CCCCCCCCCCCCCCC	20.43	23401153
704	Ubiquitination	YGGLTGGSSRGPPVT CCCCCCCCCCCCCCC	20.43	22817900
704 (in isoform 4)	Phosphorylation	-	20.43	24211406
705	Phosphorylation	GGLTGGSSRGPPVTP CCCCCCCCCCCCCCC	44.52	23927012
706	Methylation	GLTGGSSRGPPVTPS CCCCCCCCCCCCCCC	64.43	-
707	Ubiquitination	LTGGSSRGPPVTPSS CCCCCCCCCCCCCCH	32.58	24816145
708 (in isoform 4)	Phosphorylation	-	21.05	26270265
709	Ubiquitination	GGSSRGPPVTPSSEK CCCCCCCCCCCCHHH	45.50	21890473
711	Phosphorylation	SSRGPPVTPSSEKRS CCCCCCCCCCHHHHC	24.19	29255136
711 (in isoform 3)	Phosphorylation	-	24.19	18669648
711 (in isoform 4)	Phosphorylation	-	24.19	28111955
712 (in isoform 4)	Phosphorylation	-	35.77	26270265
713	Phosphorylation	RGPPVTPSSEKRSKI CCCCCCCCHHHHCCC	41.59	29255136
713 (in isoform 3)	Phosphorylation	-	41.59	18669648
714	Phosphorylation	GPPVTPSSEKRSKIP CCCCCCCHHHHCCCC	48.63	25159151
714 (in isoform 3)	Phosphorylation	-	48.63	18669648
716	Ubiquitination	PVTPSSEKRSKIPRS CCCCCHHHHCCCCHH	65.01	24816145
723	Phosphorylation	KRSKIPRSQGCSRET HHCCCCHHHCCCCCC	26.10	22617229
723	Ubiquitination	KRSKIPRSQGCSRET HHCCCCHHHCCCCCC	26.10	24816145
723 (in isoform 2)	Phosphorylation	-	26.10	28152594
723 (in isoform 3)	Phosphorylation	-	26.10	28152594
724	Ubiquitination	RSKIPRSQGCSRETS HCCCCHHHCCCCCCC	59.18	24816145
727	Phosphorylation	IPRSQGCSRETSPNR CCHHHCCCCCCCCCC	39.72	22617229
727	Ubiquitination	IPRSQGCSRETSPNR CCHHHCCCCCCCCCC	39.72	22817900
727 (in isoform 2)	Phosphorylation	-	39.72	28152594
727 (in isoform 3)	Phosphorylation	-	39.72	28152594
730	O-linked_Glycosylation	SQGCSRETSPNRIGL HHCCCCCCCCCCCCC	48.66	30379171
730	Phosphorylation	SQGCSRETSPNRIGL HHCCCCCCCCCCCCC	48.66	23403867
730 (in isoform 2)	Phosphorylation	-	48.66	22617229
730 (in isoform 3)	Phosphorylation	-	48.66	22617229
730 (in isoform 4)	Phosphorylation	-	48.66	28152594
731	Phosphorylation	QGCSRETSPNRIGLA HCCCCCCCCCCCCCC	18.54	20363803
731	Ubiquitination	QGCSRETSPNRIGLA HCCCCCCCCCCCCCC	18.54	24816145
731 (in isoform 2)	Phosphorylation	-	18.54	28355574
731 (in isoform 3)	Phosphorylation	-	18.54	28355574
731 (in isoform 5)	Phosphorylation	-	18.54	28152594
732	Ubiquitination	GCSRETSPNRIGLAR CCCCCCCCCCCCCCC	41.35	21890473
734	Ubiquitination	SRETSPNRIGLARSS CCCCCCCCCCCCCCC	27.95	22817900
734 (in isoform 4)	Phosphorylation	-	27.95	28152594
735	Ubiquitination	RETSPNRIGLARSSR CCCCCCCCCCCCCCC	7.24	22817900
735 (in isoform 5)	Phosphorylation	-	7.24	28152594
737	Ubiquitination	TSPNRIGLARSSRIP CCCCCCCCCCCCCCC	3.13	21890473
737 (in isoform 4)	Phosphorylation	-	3.13	22617229
738 (in isoform 4)	Phosphorylation	-	12.23	28355574
738 (in isoform 5)	Phosphorylation	-	12.23	22617229
739	Ubiquitination	PNRIGLARSSRIPRP CCCCCCCCCCCCCCC	39.96	21890473
739 (in isoform 5)	Phosphorylation	-	39.96	28355574
740	Phosphorylation	NRIGLARSSRIPRPS CCCCCCCCCCCCCCC	20.54	20068231
740	Ubiquitination	NRIGLARSSRIPRPS CCCCCCCCCCCCCCC	20.54	21890473
741	Phosphorylation	RIGLARSSRIPRPSM CCCCCCCCCCCCCCC	28.77	20068231
741	Ubiquitination	RIGLARSSRIPRPSM CCCCCCCCCCCCCCC	28.77	22817900
742	Ubiquitination	IGLARSSRIPRPSMS CCCCCCCCCCCCCCC	44.15	22817900
743	Ubiquitination	GLARSSRIPRPSMSQ CCCCCCCCCCCCCCC	3.52	22817900
745	Ubiquitination	ARSSRIPRPSMSQGC CCCCCCCCCCCCCCC	33.29	21890473
746	Ubiquitination	RSSRIPRPSMSQGCS CCCCCCCCCCCCCCC	29.09	21890473
747	Phosphorylation	SSRIPRPSMSQGCSR CCCCCCCCCCCCCCC	32.14	27732954
747	Ubiquitination	SSRIPRPSMSQGCSR CCCCCCCCCCCCCCC	32.14	21890473
748	Ubiquitination	SRIPRPSMSQGCSRD CCCCCCCCCCCCCCC	3.72	21890473
749	Phosphorylation	RIPRPSMSQGCSRDT CCCCCCCCCCCCCCC	27.97	27732954
751	Ubiquitination	PRPSMSQGCSRDTSR CCCCCCCCCCCCCCC	12.22	22817900
751 (in isoform 2)	Phosphorylation	-	12.22	24043423
751 (in isoform 3)	Phosphorylation	-	12.22	24043423
753	Phosphorylation	PSMSQGCSRDTSRES CCCCCCCCCCCCCCC	39.76	27732954
756	Phosphorylation	SQGCSRDTSRESSRD CCCCCCCCCCCCCCC	28.68	28270605
756	Ubiquitination	SQGCSRDTSRESSRD CCCCCCCCCCCCCCC	28.68	21890473
757	Phosphorylation	QGCSRDTSRESSRDT CCCCCCCCCCCCCCC	38.04	28270605
758 (in isoform 4)	Phosphorylation	-	50.32	24043423
759 (in isoform 2)	Phosphorylation	-	53.48	28450419
759 (in isoform 3)	Phosphorylation	-	53.48	28450419
759 (in isoform 5)	Phosphorylation	-	53.48	24043423
760	Phosphorylation	SRDTSRESSRDTSPA CCCCCCCCCCCCCCC	29.57	-
760 (in isoform 2)	Phosphorylation	-	29.57	28450419
760 (in isoform 3)	Phosphorylation	-	29.57	28450419
761 (in isoform 2)	Phosphorylation	-	29.44	28450419
761 (in isoform 3)	Phosphorylation	-	29.44	28450419
762	Phosphorylation	DTSRESSRDTSPARG CCCCCCCCCCCCCCC	61.58	32142685
762 (in isoform 2)	Phosphorylation	-	61.58	28450419
762 (in isoform 3)	Phosphorylation	-	61.58	28450419
764	Phosphorylation	SRESSRDTSPARGFP CCCCCCCCCCCCCCC	35.18	20860994
765	Phosphorylation	RESSRDTSPARGFPP CCCCCCCCCCCCCCC	22.35	23401153
766 (in isoform 4)	Phosphorylation	-	28.24	28450419
767 (in isoform 4)	Phosphorylation	-	24.81	28450419
767 (in isoform 5)	Phosphorylation	-	24.81	28450419
768 (in isoform 4)	Phosphorylation	-	51.15	28450419
768 (in isoform 5)	Phosphorylation	-	51.15	28450419
769	Phosphorylation	RDTSPARGFPPLDRF CCCCCCCCCCCCHHC	41.33	32142685
769 (in isoform 4)	Phosphorylation	-	41.33	28450419
769 (in isoform 5)	Phosphorylation	-	41.33	28450419
770	Phosphorylation	DTSPARGFPPLDRFG CCCCCCCCCCCHHCC	4.73	32142685
770	Ubiquitination	DTSPARGFPPLDRFG CCCCCCCCCCCHHCC	4.73	22817900
770 (in isoform 5)	Phosphorylation	-	4.73	28450419
771	Ubiquitination	TSPARGFPPLDRFGL CCCCCCCCCCHHCCC	31.22	22817900
775	Ubiquitination	RGFPPLDRFGLGQPG CCCCCCHHCCCCCCC	34.90	21890473
776	Ubiquitination	GFPPLDRFGLGQPGR CCCCCHHCCCCCCCC	10.66	21890473
777 (in isoform 2)	Phosphorylation	-	29.77	24043423
777 (in isoform 3)	Phosphorylation	-	29.77	24043423
779	Ubiquitination	PLDRFGLGQPGRIPG CCHHCCCCCCCCCCC	31.83	22817900
784	Ubiquitination	GLGQPGRIPGSVNAM CCCCCCCCCCCCCHH	5.85	21890473
784 (in isoform 4)	Phosphorylation	-	5.85	24043423
785 (in isoform 5)	Phosphorylation	-	27.87	24043423
787	Phosphorylation	QPGRIPGSVNAMRVL CCCCCCCCCCHHCEE	13.57	25159151
791	Sulfoxidation	IPGSVNAMRVLSTST CCCCCCHHCEECCCC	2.28	21406390
795	Phosphorylation	VNAMRVLSTSTDLEA CCHHCEECCCCCHHH	19.91	27273156
795	Ubiquitination	VNAMRVLSTSTDLEA CCHHCEECCCCCHHH	19.91	22817900
795 (in isoform 2)	Phosphorylation	-	19.91	29507054
795 (in isoform 3)	Phosphorylation	-	19.91	29507054
796	Phosphorylation	NAMRVLSTSTDLEAA CHHCEECCCCCHHHH	31.33	26846344
797	Phosphorylation	AMRVLSTSTDLEAAV HHCEECCCCCHHHHH	19.29	19664994
798	Phosphorylation	MRVLSTSTDLEAAVA HCEECCCCCHHHHHH	44.70	26846344
800	Ubiquitination	VLSTSTDLEAAVADA EECCCCCHHHHHHHH	4.96	21890473
801 (in isoform 4)	Phosphorylation	-	37.07	25849741
803 (in isoform 5)	Phosphorylation	-	6.40	29507054
816	Phosphorylation	KKPVRRRYEPYGMYS HCCHHHHCCCCCCCC	21.31	26846344
819	Phosphorylation	VRRRYEPYGMYSDDD HHHHCCCCCCCCCCC	11.55	28450419
822	Phosphorylation	RYEPYGMYSDDDANS HCCCCCCCCCCCCCC	12.46	28450419
823	Phosphorylation	YEPYGMYSDDDANSD CCCCCCCCCCCCCCC	26.18	23401153
828	Ubiquitination	MYSDDDANSDASSVC CCCCCCCCCCHHHHH	47.63	21890473
829	Phosphorylation	YSDDDANSDASSVCS CCCCCCCCCHHHHHC	35.95	28450419
832	Phosphorylation	DDANSDASSVCSERS CCCCCCHHHHHCCCC	28.44	26846344
833	Phosphorylation	DANSDASSVCSERSY CCCCCHHHHHCCCCC	28.94	26846344
836	Phosphorylation	SDASSVCSERSYGSR CCHHHHHCCCCCCCC	33.61	26846344
836	Ubiquitination	SDASSVCSERSYGSR CCHHHHHCCCCCCCC	33.61	21890473
837	Ubiquitination	DASSVCSERSYGSRN CHHHHHCCCCCCCCC	40.28	21890473
842	Phosphorylation	CSERSYGSRNGGIPH HCCCCCCCCCCCCCC	17.84	24961811
843	Methylation	SERSYGSRNGGIPHY CCCCCCCCCCCCCCC	41.26	-
844	Ubiquitination	ERSYGSRNGGIPHYL CCCCCCCCCCCCCCC	55.53	21890473
845	Ubiquitination	RSYGSRNGGIPHYLR CCCCCCCCCCCCCCC	34.01	21890473
845 (in isoform 2)	Ubiquitination	-	34.01	21890473
845 (in isoform 3)	Ubiquitination	-	34.01	21890473
851	Ubiquitination	NGGIPHYLRQTEDVA CCCCCCCCCCCHHHH	2.73	-
851	Ubiquitination	NGGIPHYLRQTEDVA CCCCCCCCCCCHHHH	2.73	21890473
852	Ubiquitination	GGIPHYLRQTEDVAE CCCCCCCCCCHHHHH	33.92	21890473
853	Ubiquitination	GIPHYLRQTEDVAEV CCCCCCCCCHHHHHH	46.80	21890473
853	Ubiquitination	GIPHYLRQTEDVAEV CCCCCCCCCHHHHHH	46.80	21890473
853	Ubiquitination	GIPHYLRQTEDVAEV CCCCCCCCCHHHHHH	46.80	21890473
861	Ubiquitination	TEDVAEVLNHCASSN CHHHHHHHHHHHCCC	2.45	21890473
869	Ubiquitination	NHCASSNWSERKEGL HHHHCCCHHHHHHHH	11.97	21890473
872	Methylation	ASSNWSERKEGLLGL HCCCHHHHHHHHHHH	36.49	-
872	Ubiquitination	ASSNWSERKEGLLGL HCCCHHHHHHHHHHH	36.49	21890473
873	Ubiquitination	SSNWSERKEGLLGLQ CCCHHHHHHHHHHHH	52.67	21890473
873 (in isoform 1)	Ubiquitination	-	52.67	21890473
881	Ubiquitination	EGLLGLQNLLKSQRT HHHHHHHHHHHHCCC	53.00	21890473
884	Ubiquitination	LGLQNLLKSQRTLSR HHHHHHHHHCCCCCH	47.94	21890473
889	Ubiquitination	LLKSQRTLSRVELKR HHHHCCCCCHHHHHH	3.16	21890473
891	Ubiquitination	KSQRTLSRVELKRLC HHCCCCCHHHHHHHH	29.10	21890473
892	Ubiquitination	SQRTLSRVELKRLCE HCCCCCHHHHHHHHH	10.18	21890473
897	Ubiquitination	SRVELKRLCEIFTRM CHHHHHHHHHHHHHH	2.69	21890473
898	Ubiquitination	RVELKRLCEIFTRMF HHHHHHHHHHHHHHH	4.35	21890473
899	Ubiquitination	VELKRLCEIFTRMFA HHHHHHHHHHHHHHC	45.81	21890473
900	Ubiquitination	ELKRLCEIFTRMFAD HHHHHHHHHHHHHCC	4.10	21890473
905	Ubiquitination	CEIFTRMFADPHSKR HHHHHHHHCCHHHHH	6.68	21890473
908	Ubiquitination	FTRMFADPHSKRVFS HHHHHCCHHHHHHHH	30.16	21890473
927	Ubiquitination	TLVDFIIIHKDDLQD HHHHHEEECCCHHHH	2.56	21890473
928	Ubiquitination	LVDFIIIHKDDLQDW HHHHEEECCCHHHHH	19.65	21890473
932	Ubiquitination	IIIHKDDLQDWLFVL EEECCCHHHHHHHHH	7.74	33845483
933	Ubiquitination	IIHKDDLQDWLFVLL EECCCHHHHHHHHHH	46.99	33845483
936	Ubiquitination	KDDLQDWLFVLLTQL CCHHHHHHHHHHHHH	2.60	21890473
939	Ubiquitination	LQDWLFVLLTQLLKK HHHHHHHHHHHHHHH	3.16	33845483
941	Ubiquitination	DWLFVLLTQLLKKMG HHHHHHHHHHHHHCC	17.01	33845483
950	Ubiquitination	LLKKMGADLLGSVQA HHHHCCCHHHHHHHH	36.38	22817900
952	Ubiquitination	KKMGADLLGSVQAKV HHCCCHHHHHHHHHH	5.03	21890473
954	Phosphorylation	MGADLLGSVQAKVQK CCCHHHHHHHHHHHH	15.83	23532336
955	Ubiquitination	GADLLGSVQAKVQKA CCHHHHHHHHHHHHH	6.43	21890473
958	Ubiquitination	LLGSVQAKVQKALDV HHHHHHHHHHHHHHC	28.27	22817900
959	Ubiquitination	LGSVQAKVQKALDVT HHHHHHHHHHHHHCC	8.71	22817900
961	Ubiquitination	SVQAKVQKALDVTRD HHHHHHHHHHHCCCC	54.63	33845483
963	Ubiquitination	QAKVQKALDVTRDSF HHHHHHHHHCCCCCC	7.58	21890473
964	Ubiquitination	AKVQKALDVTRDSFP HHHHHHHHCCCCCCC	44.60	21890473
965	Ubiquitination	KVQKALDVTRDSFPF HHHHHHHCCCCCCCH	5.00	32015554
966	Ubiquitination	VQKALDVTRDSFPFD HHHHHHCCCCCCCHH	28.55	22817900
967	Ubiquitination	QKALDVTRDSFPFDQ HHHHHCCCCCCCHHH	37.11	22817900
968	Ubiquitination	KALDVTRDSFPFDQQ HHHHCCCCCCCHHHH	45.31	33845483
969	Phosphorylation	ALDVTRDSFPFDQQF HHHCCCCCCCHHHHH	31.37	22817900
971	Ubiquitination	DVTRDSFPFDQQFNI HCCCCCCCHHHHHHH	35.54	21890473
972	Ubiquitination	VTRDSFPFDQQFNIL CCCCCCCHHHHHHHH	14.43	21890473
972 (in isoform 2)	Ubiquitination	-	14.43	21890473
973	Ubiquitination	TRDSFPFDQQFNILM CCCCCCHHHHHHHHH	41.43	22817900
974	Ubiquitination	RDSFPFDQQFNILMR CCCCCHHHHHHHHHH	50.58	22817900
975	Ubiquitination	DSFPFDQQFNILMRF CCCCHHHHHHHHHHH	34.89	22817900
978	Ubiquitination	PFDQQFNILMRFIVD CHHHHHHHHHHHHHC	3.18	-
978	Ubiquitination	PFDQQFNILMRFIVD CHHHHHHHHHHHHHC	3.18	21890473
979	Ubiquitination	FDQQFNILMRFIVDQ HHHHHHHHHHHHHCC	1.80	21890473
980	Ubiquitination	DQQFNILMRFIVDQT HHHHHHHHHHHHCCC	2.66	21890473
980	Ubiquitination	DQQFNILMRFIVDQT HHHHHHHHHHHHCCC	2.66	21890473
980	Ubiquitination	DQQFNILMRFIVDQT HHHHHHHHHHHHCCC	2.66	21890473
982	Ubiquitination	QFNILMRFIVDQTQT HHHHHHHHHHCCCCC	3.88	22817900
983	Ubiquitination	FNILMRFIVDQTQTP HHHHHHHHHCCCCCC	2.05	22817900
987	Phosphorylation	MRFIVDQTQTPNLKV HHHHHCCCCCCCHHH	29.91	22817900
987	Ubiquitination	MRFIVDQTQTPNLKV HHHHHCCCCCCCHHH	29.91	21890473
988	Ubiquitination	RFIVDQTQTPNLKVK HHHHCCCCCCCHHHH	49.69	21890473
990	Ubiquitination	IVDQTQTPNLKVKVA HHCCCCCCCHHHHHH	34.05	22817900
991	Ubiquitination	VDQTQTPNLKVKVAI HCCCCCCCHHHHHHH	56.75	22817900
994	Ubiquitination	TQTPNLKVKVAILKY CCCCCHHHHHHHHHH	7.31	22817900
995	Ubiquitination	QTPNLKVKVAILKYI CCCCHHHHHHHHHHH	25.10	21890473
995 (in isoform 3)	Ubiquitination	-	25.10	21890473
996	Ubiquitination	TPNLKVKVAILKYIE CCCHHHHHHHHHHHH	4.48	21890473
999	Ubiquitination	LKVKVAILKYIESLA HHHHHHHHHHHHHHH	2.19	21890473
1000	Ubiquitination	KVKVAILKYIESLAR HHHHHHHHHHHHHHH	37.76	21890473
1000 (in isoform 1)	Ubiquitination	-	37.76	21890473
1001	Phosphorylation	VKVAILKYIESLARQ HHHHHHHHHHHHHHC	13.38	22468782
1003	Ubiquitination	VAILKYIESLARQMD HHHHHHHHHHHHCCC	36.29	22817900
1004	Phosphorylation	AILKYIESLARQMDP HHHHHHHHHHHCCCC	20.12	22468782
1008	Ubiquitination	YIESLARQMDPTDFV HHHHHHHCCCCCCCC	34.72	21890473
1011	Ubiquitination	SLARQMDPTDFVNSS HHHHCCCCCCCCCCH	28.64	22817900
1016	Ubiquitination	MDPTDFVNSSETRLA CCCCCCCCCHHHHHH	39.55	21890473
1019	Ubiquitination	TDFVNSSETRLAVSR CCCCCCHHHHHHEEE	37.46	22817900
1024	Ubiquitination	SSETRLAVSRIITWT CHHHHHHEEEEHHHC	4.71	21890473
1027	Ubiquitination	TRLAVSRIITWTTEP HHHHEEEEHHHCCCC	2.28	22817900
1029	Phosphorylation	LAVSRIITWTTEPKS HHEEEEHHHCCCCCC	17.87	21406692
1031	Phosphorylation	VSRIITWTTEPKSSD EEEEHHHCCCCCCCH	16.78	21406692
1032	Phosphorylation	SRIITWTTEPKSSDV EEEHHHCCCCCCCHH	41.68	21406692
1032	Ubiquitination	SRIITWTTEPKSSDV EEEHHHCCCCCCCHH	41.68	21890473
1036	Phosphorylation	TWTTEPKSSDVRKAA HHCCCCCCCHHHHHH	42.35	21406692
1037	Phosphorylation	WTTEPKSSDVRKAAQ HCCCCCCCHHHHHHH	46.37	21406692
1047	Ubiquitination	RKAAQIVLISLFELN HHHHHHHHHHHHHCC	2.05	29967540
1050	Ubiquitination	AQIVLISLFELNTPE HHHHHHHHHHCCCHH	2.83	22817900
1053	Ubiquitination	VLISLFELNTPEFTM HHHHHHHCCCHHHHH	7.29	29967540
1054	Ubiquitination	LISLFELNTPEFTML HHHHHHCCCHHHHHH	46.52	29967540
1055	Ubiquitination	ISLFELNTPEFTMLL HHHHHCCCHHHHHHH	36.50	21890473
1059	Phosphorylation	ELNTPEFTMLLGALP HCCCHHHHHHHCCCC	12.78	-
1060	Ubiquitination	LNTPEFTMLLGALPK CCCHHHHHHHCCCCC	3.36	29967540
1062	Phosphorylation	TPEFTMLLGALPKTF CHHHHHHHCCCCCCC	2.34	32142685
1062	Ubiquitination	TPEFTMLLGALPKTF CHHHHHHHCCCCCCC	2.34	29967540
1063	Phosphorylation	PEFTMLLGALPKTFQ HHHHHHHCCCCCCCC	22.55	32142685
1068	Phosphorylation	LLGALPKTFQDGATK HHCCCCCCCCCHHHH	25.29	-
1069	Phosphorylation	LGALPKTFQDGATKL HCCCCCCCCCHHHHH	8.55	32142685
1071	Phosphorylation	ALPKTFQDGATKLLH CCCCCCCCHHHHHHH	44.49	32142685
1074	Phosphorylation	KTFQDGATKLLHNHL CCCCCHHHHHHHHHH	27.96	-
1075	Ubiquitination	TFQDGATKLLHNHLK CCCCHHHHHHHHHHH	48.82	29967540
1077 (in isoform 2)	Phosphorylation	-	3.97	30624053
1078 (in isoform 2)	Phosphorylation	-	30.05	30624053
1080 (in isoform 2)	Phosphorylation	-	27.68	28450419
1081 (in isoform 2)	Phosphorylation	-	7.34	28450419
1082	Ubiquitination	KLLHNHLKNSSNTSV HHHHHHHHCCCCCCC	47.43	29967540
1083 (in isoform 3)	Phosphorylation	-	57.96	18669648
1083 (in isoform 4)	Phosphorylation	-	57.96	30624053
1084	Phosphorylation	LHNHLKNSSNTSVGS HHHHHHCCCCCCCCC	24.31	29255136
1084 (in isoform 2)	Phosphorylation	-	24.31	28450419
1084 (in isoform 4)	Phosphorylation	-	24.31	30624053
1085	Phosphorylation	HNHLKNSSNTSVGSP HHHHHCCCCCCCCCC	54.22	29255136
1085 (in isoform 2)	Phosphorylation	-	54.22	28450419
1085 (in isoform 5)	Phosphorylation	-	54.22	30624053
1086 (in isoform 4)	Phosphorylation	-	35.87	28450419
1086 (in isoform 5)	Phosphorylation	-	35.87	30624053
1087	Phosphorylation	HLKNSSNTSVGSPSN HHHCCCCCCCCCCCC	27.08	29255136
1087 (in isoform 2)	Phosphorylation	-	27.08	28450419
1087 (in isoform 4)	Phosphorylation	-	27.08	28450419
1088	Phosphorylation	LKNSSNTSVGSPSNT HHCCCCCCCCCCCCC	28.82	29255136
1088 (in isoform 5)	Phosphorylation	-	28.82	28450419
1089	Phosphorylation	KNSSNTSVGSPSNTI HCCCCCCCCCCCCCC	9.18	32142685
1089 (in isoform 5)	Phosphorylation	-	9.18	28450419
1090	Phosphorylation	NSSNTSVGSPSNTIG CCCCCCCCCCCCCCC	33.34	32142685
1090 (in isoform 2)	Phosphorylation	-	33.34	28450419
1090 (in isoform 4)	Phosphorylation	-	33.34	28450419
1091	Phosphorylation	SSNTSVGSPSNTIGR CCCCCCCCCCCCCCC	24.01	19664994
1091 (in isoform 4)	Phosphorylation	-	24.01	28450419
1092 (in isoform 5)	Phosphorylation	-	26.18	28450419
1093	Phosphorylation	NTSVGSPSNTIGRTP CCCCCCCCCCCCCCC	48.58	29255136
1093 (in isoform 4)	Phosphorylation	-	48.58	28450419
1093 (in isoform 5)	Phosphorylation	-	48.58	28450419
1095	Phosphorylation	SVGSPSNTIGRTPSR CCCCCCCCCCCCCCC	29.19	29255136
1095 (in isoform 2)	Phosphorylation	-	29.19	28387310
1095 (in isoform 5)	Phosphorylation	-	29.19	28450419
1096	Phosphorylation	VGSPSNTIGRTPSRH CCCCCCCCCCCCCCC	4.04	32142685
1096 (in isoform 4)	Phosphorylation	-	4.04	28450419
1097 (in isoform 2)	Phosphorylation	-	25.93	28450419
1098	Phosphorylation	SPSNTIGRTPSRHTS CCCCCCCCCCCCCCC	39.34	32142685
1098 (in isoform 5)	Phosphorylation	-	39.34	28450419
1099	Phosphorylation	PSNTIGRTPSRHTSS CCCCCCCCCCCCCCC	22.02	25159151
1100 (in isoform 3)	Phosphorylation	-	28.18	30624053
1101	Phosphorylation	NTIGRTPSRHTSSRT CCCCCCCCCCCCCCC	35.76	28450419
1101 (in isoform 2)	Phosphorylation	-	35.76	28450419
1101 (in isoform 3)	Phosphorylation	-	35.76	30624053
1101 (in isoform 4)	Phosphorylation	-	35.76	28387310
1103 (in isoform 2)	Phosphorylation	-	34.14	28450419
1103 (in isoform 3)	Phosphorylation	-	34.14	28450419
1103 (in isoform 4)	Phosphorylation	-	34.14	28450419
1103 (in isoform 5)	Phosphorylation	-	34.14	28387310
1104 (in isoform 3)	Phosphorylation	-	27.56	28450419
1105 (in isoform 5)	Phosphorylation	-	16.23	28450419
1107	Ubiquitination	PSRHTSSRTSPLTSP CCCCCCCCCCCCCCC	38.70	21890473
1107 (in isoform 3)	Phosphorylation	-	38.70	28450419
1107 (in isoform 4)	Phosphorylation	-	38.70	28450419
1108 (in isoform 2)	Phosphorylation	-	36.32	27251275
1108 (in isoform 3)	Phosphorylation	-	36.32	28450419
1109	Phosphorylation	RHTSSRTSPLTSPTN CCCCCCCCCCCCCCC	19.46	21601212
1109 (in isoform 4)	Phosphorylation	-	19.46	28450419
1109 (in isoform 5)	Phosphorylation	-	19.46	28450419
1110 (in isoform 3)	Phosphorylation	-	38.76	28450419
1111 (in isoform 5)	Phosphorylation	-	8.09	28450419
1112	Phosphorylation	SSRTSPLTSPTNCSH CCCCCCCCCCCCCCC	35.72	18669648
1112 (in isoform 2)	Phosphorylation	-	35.72	27251275
1113	Phosphorylation	SRTSPLTSPTNCSHG CCCCCCCCCCCCCCC	37.09	18669648
1113 (in isoform 2)	Phosphorylation	-	37.09	27251275
1113 (in isoform 3)	Phosphorylation	-	37.09	28450419
1114 (in isoform 2)	Phosphorylation	-	23.54	27251275
1114 (in isoform 4)	Phosphorylation	-	23.54	27251275
1115	Ubiquitination	TSPLTSPTNCSHGGL CCCCCCCCCCCCCCC	48.93	21890473
1116	Ubiquitination	SPLTSPTNCSHGGLS CCCCCCCCCCCCCCC	28.78	21890473
1116 (in isoform 5)	Phosphorylation	-	28.78	27251275
1118	Phosphorylation	LTSPTNCSHGGLSPS CCCCCCCCCCCCCHH	27.51	32142685
1118 (in isoform 3)	Phosphorylation	-	27.51	28387310
1118 (in isoform 4)	Phosphorylation	-	27.51	27251275
1119 (in isoform 4)	Phosphorylation	-	36.22	27251275
1120 (in isoform 3)	Phosphorylation	-	23.57	28450419
1120 (in isoform 4)	Phosphorylation	-	23.57	27251275
1120 (in isoform 5)	Phosphorylation	-	23.57	27251275
1121 (in isoform 5)	Phosphorylation	-	19.98	27251275
1122 (in isoform 5)	Phosphorylation	-	8.89	27251275
1123	Phosphorylation	NCSHGGLSPSRLWGW CCCCCCCCHHHHCCC	24.89	18669648
1123	Ubiquitination	NCSHGGLSPSRLWGW CCCCCCCCHHHHCCC	24.89	21890473
1124	Ubiquitination	CSHGGLSPSRLWGWS CCCCCCCHHHHCCCC	28.63	21890473
1124 (in isoform 2)	Ubiquitination	-	28.63	21890473
1124 (in isoform 3)	Phosphorylation	-	28.63	28450419
1125	Phosphorylation	SHGGLSPSRLWGWSA CCCCCCHHHHCCCCC	36.31	32142685
1126 (in isoform 3)	Phosphorylation	-	37.53	28450419
1128	Phosphorylation	GLSPSRLWGWSADGL CCCHHHHCCCCCCHH	12.71	32142685
1129	Phosphorylation	LSPSRLWGWSADGLA CCHHHHCCCCCCHHH	17.04	32142685
1130	Ubiquitination	SPSRLWGWSADGLAK CHHHHCCCCCCHHHH	4.45	-
1130	Ubiquitination	SPSRLWGWSADGLAK CHHHHCCCCCCHHHH	4.45	21890473
1131	Ubiquitination	PSRLWGWSADGLAKH HHHHCCCCCCHHHHC	16.73	21890473
1131 (in isoform 3)	Phosphorylation	-	16.73	27251275
1132	Ubiquitination	SRLWGWSADGLAKHP HHHCCCCCCHHHHCC	14.37	21890473
1132	Ubiquitination	SRLWGWSADGLAKHP HHHCCCCCCHHHHCC	14.37	21890473
1132	Ubiquitination	SRLWGWSADGLAKHP HHHCCCCCCHHHHCC	14.37	21890473
1135	Phosphorylation	WGWSADGLAKHPPPF CCCCCCHHHHCCCCC	6.21	32142685
1135 (in isoform 3)	Phosphorylation	-	6.21	27251275
1136 (in isoform 3)	Phosphorylation	-	17.40	27251275
1137	Phosphorylation	WSADGLAKHPPPFSQ CCCCHHHHCCCCCCC	62.78	32142685
1137 (in isoform 3)	Phosphorylation	-	62.78	27251275
1139	Ubiquitination	ADGLAKHPPPFSQPN CCHHHHCCCCCCCCC	37.24	21890473
1140	Ubiquitination	DGLAKHPPPFSQPNS CHHHHCCCCCCCCCC	42.14	21890473
1147	Ubiquitination	PPFSQPNSIPTAPSH CCCCCCCCCCCCCCH	36.31	21890473
1147 (in isoform 3)	Ubiquitination	-	36.31	21890473
1148	Ubiquitination	PFSQPNSIPTAPSHK CCCCCCCCCCCCCHH	4.46	21890473
1151	Ubiquitination	QPNSIPTAPSHKALR CCCCCCCCCCHHHHH	9.76	21890473
1157	Ubiquitination	TAPSHKALRRSYSPS CCCCHHHHHHHCCHH	5.80	21890473
1158	Ubiquitination	APSHKALRRSYSPSM CCCHHHHHHHCCHHH	30.29	21890473
1160	Ubiquitination	SHKALRRSYSPSMLD CHHHHHHHCCHHHHC	24.43	21890473
1161	Phosphorylation	HKALRRSYSPSMLDY HHHHHHHCCHHHHCC	23.84	30576142
1164	Phosphorylation	LRRSYSPSMLDYDTE HHHHCCHHHHCCCCC	26.49	32142685
1168	Ubiquitination	YSPSMLDYDTENLNS CCHHHHCCCCCCCCH	22.32	21890473
1174	Ubiquitination	DYDTENLNSEEIYSS CCCCCCCCHHHHHHH	59.98	21890473
1175	Phosphorylation	YDTENLNSEEIYSSL CCCCCCCHHHHHHHH	39.51	30576142
1176	Ubiquitination	DTENLNSEEIYSSLR CCCCCCHHHHHHHHH	47.55	21890473
1179	Phosphorylation	NLNSEEIYSSLRGVT CCCHHHHHHHHHHHH	8.76	25884760
1184	Ubiquitination	EIYSSLRGVTEAIEK HHHHHHHHHHHHHHH	35.67	21890473
1191	Ubiquitination	GVTEAIEKFSFRSQE HHHHHHHHHCCCCHH	39.95	23000965
1191 (in isoform 1)	Ubiquitination	-	39.95	21890473
1193	Phosphorylation	TEAIEKFSFRSQEDL HHHHHHHCCCCHHHH	30.71	23927012
1196	Phosphorylation	IEKFSFRSQEDLNEP HHHHCCCCHHHHCCC	35.59	19664994
1211	Ubiquitination	IKRDGKKECDIVSRD CCCCCCCCCCEEECC	40.69	29967540
1215	Ubiquitination	GKKECDIVSRDGGAA CCCCCCEEECCCCCC	2.16	29967540
1216	Phosphorylation	KKECDIVSRDGGAAS CCCCCEEECCCCCCC	25.62	22199227
1217	Ubiquitination	KECDIVSRDGGAASP CCCCEEECCCCCCCC	35.38	29967540
1219	Ubiquitination	CDIVSRDGGAASPAT CCEEECCCCCCCCCC	26.91	29967540
1221	Ubiquitination	IVSRDGGAASPATEG EEECCCCCCCCCCCC	15.42	29967540
1223	Phosphorylation	SRDGGAASPATEGRG ECCCCCCCCCCCCCC	17.97	29255136
1223	Ubiquitination	SRDGGAASPATEGRG ECCCCCCCCCCCCCC	17.97	29967540
1226	Phosphorylation	GGAASPATEGRGGSE CCCCCCCCCCCCCCC	42.21	27794612
1229	Methylation	ASPATEGRGGSEVEG CCCCCCCCCCCCCCC	39.81	-
1232	Phosphorylation	ATEGRGGSEVEGGRT CCCCCCCCCCCCCCC	41.09	28450419
1241	Ubiquitination	VEGGRTALDNKTSLL CCCCCCCCCCCCCCC	8.03	21890473
1245	Phosphorylation	RTALDNKTSLLNTQP CCCCCCCCCCCCCCC	30.75	-
1246	Phosphorylation	TALDNKTSLLNTQPP CCCCCCCCCCCCCCC	32.25	28555341
1250	Phosphorylation	NKTSLLNTQPPRAFP CCCCCCCCCCCCCCC	42.28	24173317
1262	Ubiquitination	AFPGPRARDYNPYPY CCCCCCCCCCCCCCC	48.50	33845483
1263	Ubiquitination	FPGPRARDYNPYPYS CCCCCCCCCCCCCCC	46.72	33845483
1264	Phosphorylation	PGPRARDYNPYPYSD CCCCCCCCCCCCCCH	16.69	-
1267	Phosphorylation	RARDYNPYPYSDAIN CCCCCCCCCCCHHCC	15.91	28796482
1269	Phosphorylation	RDYNPYPYSDAINTY CCCCCCCCCHHCCCC	17.22	28796482
1269	Ubiquitination	RDYNPYPYSDAINTY CCCCCCCCCHHCCCC	17.22	33845483
1270	Phosphorylation	DYNPYPYSDAINTYD CCCCCCCCHHCCCCC	18.96	28796482
1271	Ubiquitination	YNPYPYSDAINTYDK CCCCCCCHHCCCCCH	45.70	33845483
1275	Phosphorylation	PYSDAINTYDKTALK CCCHHCCCCCHHHHH	27.30	28796482
1276	Phosphorylation	YSDAINTYDKTALKE CCHHCCCCCHHHHHH	15.79	28796482
1278	Ubiquitination	DAINTYDKTALKEAV HHCCCCCHHHHHHHH	25.86	29967540
1282	Ubiquitination	TYDKTALKEAVFDDD CCCHHHHHHHHCCCC	40.96	29967540
1298	Ubiquitination	EQLRDVPIDHSDLVA HHHCCCCCCHHHHHH	8.16	33845483
1322	Malonylation	NERVEERKGALLELL HHHHHHHHHHHHHHH	52.38	32601280
1330	Ubiquitination	GALLELLKITREDSL HHHHHHHHHHCCCCC	55.44	33845483
1346	Phosphorylation	VWEEHFKTILLLLLE HHHHHHHHHHHHHHH	18.86	21406692
1354	Phosphorylation	ILLLLLETLGDKDHS HHHHHHHHHCCCCHH	35.69	21406692
1361	Phosphorylation	TLGDKDHSIRALALR HHCCCCHHHHHHHHH	24.73	20860994
1384	Phosphorylation	QPARFKNYAELTIMK CCHHHCCHHHHHHHH	11.31	22985185
1388	Phosphorylation	FKNYAELTIMKTLEA HCCHHHHHHHHHHHH	15.55	22985185
1399	Phosphorylation	TLEAHKDSHKEVVRA HHHHCCCCHHHHHHH	41.06	30576142
1413	Phosphorylation	AAEEAASTLASSIHP HHHHHHHHHHHHCCH	22.93	30576142
1451	Ubiquitination	KMQTKVVERIAKESL HHHHHHHHHHHHHHH	41.16	33845483
1452	Ubiquitination	MQTKVVERIAKESLL HHHHHHHHHHHHHHH	23.66	33845483
1458	Ubiquitination	ERIAKESLLQLLVDI HHHHHHHHHHHHHHH	3.56	33845483
1460	Ubiquitination	IAKESLLQLLVDIIP HHHHHHHHHHHHHHH	37.74	33845483
1484	Phosphorylation	ESSVRKASVFCLVAI HHHHHHHHHHHHHHH	20.82	21406692
1487	Ubiquitination	VRKASVFCLVAIYSV HHHHHHHHHHHHHHH	2.54	33845483
1492	Phosphorylation	VFCLVAIYSVIGEDL HHHHHHHHHHHCCCC	6.27	21406692
1493	Phosphorylation	FCLVAIYSVIGEDLK HHHHHHHHHHCCCCH	10.93	21406692
1517	Phosphorylation	KMKLLNLYIKRAQTT HHHHHHHHHHHHHCC	11.88	-
1519	Ubiquitination	KLLNLYIKRAQTTNS HHHHHHHHHHHCCCC	28.29	33845483
1523	Phosphorylation	LYIKRAQTTNSNSSS HHHHHHHCCCCCCCC	27.28	28450419
1524	Phosphorylation	YIKRAQTTNSNSSSS HHHHHHCCCCCCCCC	25.27	25262027
1526	Phosphorylation	KRAQTTNSNSSSSSD HHHHCCCCCCCCCCC	35.68	26434776
1528	Phosphorylation	AQTTNSNSSSSSDVS HHCCCCCCCCCCCCC	31.27	26434776
1529	Phosphorylation	QTTNSNSSSSSDVST HCCCCCCCCCCCCCC	38.19	28450419
1530	Phosphorylation	TTNSNSSSSSDVSTH CCCCCCCCCCCCCCC	33.41	25849741
1531	Phosphorylation	TNSNSSSSSDVSTHS CCCCCCCCCCCCCCC	32.29	28450419
1532	Phosphorylation	NSNSSSSSDVSTHS- CCCCCCCCCCCCCC-	43.93	26434776
1535	Phosphorylation	SSSSSDVSTHS---- CCCCCCCCCCC----	25.95	25627689
1536	Phosphorylation	SSSSDVSTHS----- CCCCCCCCCC-----	26.45	25262027
1538	Phosphorylation	SSDVSTHS------- CCCCCCCC-------	41.84	25627689

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CLAP1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CLAP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CLAP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZW10_HUMAN	ZW10	physical	22939629
GCC2_HUMAN	GCC2	physical	26344197
CLIP2_HUMAN	CLIP2	physical	11290329

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CLAP1_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-600; SER-636; SER-646;SER-688; SER-797 AND SER-1091, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1223, AND MASSSPECTROMETRY.	19369195 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-594; SER-600; SER-646;SER-647; SER-649; THR-651; SER-797 AND SER-1091, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-600; SER-646; SER-647;SER-649; THR-656; SER-688; SER-695; THR-711; SER-714; SER-1091 ANDTHR-1099, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-646; SER-1091 ANDTHR-1099, AND MASS SPECTROMETRY.	18220336 [Abstract]
"Phosphoproteome of resting human platelets."; Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J.,Schuetz C., Walter U., Gambaryan S., Sickmann A.; J. Proteome Res. 7:526-534(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1196, AND MASSSPECTROMETRY.	18088087 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-559 AND SER-568, ANDMASS SPECTROMETRY.	17525332 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-609 AND SER-1223, ANDMASS SPECTROMETRY.	15302935 [Abstract]