CCD70_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCD70_HUMAN
• UniProt AC: Q6NSX1
• Protein Name: Coiled-coil domain-containing protein 70
• Gene Name: CCDC70
• Organism: Homo sapiens (Human).
• Sequence Length: 233
• Subcellular Localization: Secreted .
• Protein Sequence: MATPPFRLIRKMFSFKVSRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLEDGPHNANRGQRLLAFSRGRA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	RLIRKMFSFKVSRWM HHHHHHHHHHHHHHH	22.21	24719451
39	Acetylation	SSPSIRQKKLMHKLQ CCHHHHHHHHHHHHH	37.72	7825247
44	Acetylation	RQKKLMHKLQEEKAF HHHHHHHHHHHHHHH	37.59	7825257
56	Acetylation	KAFREEMKIFREKIE HHHHHHHHHHHHHHH	41.81	7825267
106	Phosphorylation	TFWKEEKSFWEMEKS HHHHHHHHHHHHHHH	38.58	-
125	Phosphorylation	EKTFWKKYRTFWKED HHHHHHHHHHHHHHC	15.91	-
127	Phosphorylation	TFWKKYRTFWKEDKA HHHHHHHHHHHHCHH	30.66	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCD70_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCD70_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCD70_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FATE1_HUMAN	FATE1	physical	25416956
FAM9B_HUMAN	FAM9B	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.