CAZ_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CAZ_DROME
• UniProt AC: Q27294
• Protein Name: RNA-binding protein cabeza
• Gene Name: caz
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 399
• Subcellular Localization: Nucleus .
• Protein Description: May participate in a function common to the expression of most genes transcribed by RNA polymerase II..
• Protein Sequence: MERGGYGGGSGQGYNNFAVPPPNYQQMPNKTGNYNEPPPNYGKQGGGYDSGSGHRGSGGSGNGGGGGGSWNDRGGNSYGNGGASKDSYNKGHGGYSGGGGGGGGGGGGGSGGNDMITQEDTIFVSGMDPSTTEQDIETHFGAIGIIKKDKRTMKPKIWLYKNKETGASKGEATVTYDDTNAAQSAIEWFDGRDFNGNAIKVSLAQRQNNWNKGGGGGGGGGGRGGFGGRRGGGGGGGGGGGGGGRFDRGGGGGGGRYDRGGGGGGGGGGGNVQPRDGDWKCNSCNNTNFAWRNECNRCKTPKGDDEGSSGGGGGGGYGGGGGGGGYDRGNDRGSGGGGYHNRDRGGNSQGGGGGGGGGGGYSRFNDNNGGGRGGRGGGGGNRRDGGPMRNDGGMRSRPY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Acetylation	EPPPNYGKQGGGYDS CCCCCCCCCCCCCCC	35.10	21791702
50	Phosphorylation	KQGGGYDSGSGHRGS CCCCCCCCCCCCCCC	26.78	19429919
52	Phosphorylation	GGGYDSGSGHRGSGG CCCCCCCCCCCCCCC	35.06	19429919
57	Phosphorylation	SGSGHRGSGGSGNGG CCCCCCCCCCCCCCC	39.68	19429919
60	Phosphorylation	GHRGSGGSGNGGGGG CCCCCCCCCCCCCCC	32.39	19429919
308	Phosphorylation	PKGDDEGSSGGGGGG CCCCCCCCCCCCCCC	24.62	19429919
309	Phosphorylation	KGDDEGSSGGGGGGG CCCCCCCCCCCCCCC	52.92	19429919
334	Phosphorylation	DRGNDRGSGGGGYHN CCCCCCCCCCCCCCC	34.85	19429919
348	Phosphorylation	NRDRGGNSQGGGGGG CCCCCCCCCCCCCCC	33.21	21082442
361	Phosphorylation	GGGGGGGYSRFNDNN CCCCCCCCCCCCCCC	10.43	19429919
362	Phosphorylation	GGGGGGYSRFNDNNG CCCCCCCCCCCCCCC	33.40	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CAZ_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CAZ_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CAZ_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TERA_DROME	TER94	genetic	24497576
RHOM_DROME	rho	genetic	24928275

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.