UniProt ID | BBP_SCHPO | |
---|---|---|
UniProt AC | O74555 | |
Protein Name | Branchpoint-bridging protein | |
Gene Name | bpb1 | |
Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
Sequence Length | 587 | |
Subcellular Localization | Cytoplasm . Nucleus . | |
Protein Description | Necessary for the splicing of pre-mRNA. The BPB1(SF1)-u2af59-u2af23 complex has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.. | |
Protein Sequence | MLNSRSVGSTGSNNTPLGRRRFDEKPDSLPPLPDANGMSNGYRDSYKSNSRMDHRPDGYHDGRGRRAYRKHYWGHPTPIEEMLPSQMELETAVKSCMTMEQLELYSLNVRLEEITQKLRTGDVVPHHRERSPSPPPQYDNHGRRLNTREIRYKKKLEDERHRIIERAMKMVPGFRAPSDYRRPAKTQEKVYVPVKDYPEINFIGLLIGPRGHTLKDMEAKSGAKIAIRGKGSVKEGKGRSDPSVRGNMEEDLHCLVTADSEDKINHAIKLIDNVIQTAASVPEGQNDLKRNQLRQLATLNGTLRDDENQVCQNCGNVGHRRFDCPERINHTMNIVCRHCGSIGHIARDCPVRDQQPPMADSTADREYQSLMQELGGGSAISNGNGEPQKSIEFSESGAASPQAGHPPPWAAASTSVSSSTSSPAPWAKPASSAAPSNPAPWQQPAAPQSAPALSMNPSSLPPWQQPTQQSAVQPSNLVPSQNAPFIPGTSAPLPPTTFAPPGVPLPPIPGAPGMPNLNMSQPPMVPPGMALPPGMPAPFPGYPAVPAMPGIPGATAPPGAPGSYNTSESSNLNAPPGVSMPNGYSNR | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
6 | Phosphorylation | --MLNSRSVGSTGSN --CCCCCCCCCCCCC | 30.56 | 29996109 | |
9 | Phosphorylation | LNSRSVGSTGSNNTP CCCCCCCCCCCCCCC | 27.69 | 29996109 | |
10 | Phosphorylation | NSRSVGSTGSNNTPL CCCCCCCCCCCCCCC | 38.41 | 29996109 | |
12 | Phosphorylation | RSVGSTGSNNTPLGR CCCCCCCCCCCCCCC | 27.31 | 29996109 | |
15 | Phosphorylation | GSTGSNNTPLGRRRF CCCCCCCCCCCCCCC | 24.92 | 29996109 | |
131 | Phosphorylation | VPHHRERSPSPPPQY CCCCCCCCCCCCCCC | 25.61 | 28889911 | |
133 | Phosphorylation | HHRERSPSPPPQYDN CCCCCCCCCCCCCCC | 51.81 | 28889911 | |
138 | Phosphorylation | SPSPPPQYDNHGRRL CCCCCCCCCCCCCCC | 25.20 | 29996109 | |
390 | Phosphorylation | GNGEPQKSIEFSESG CCCCCCCEEEECCCC | 23.31 | 21712547 | |
394 | Phosphorylation | PQKSIEFSESGAASP CCCEEEECCCCCCCC | 20.33 | 27738172 | |
396 | Phosphorylation | KSIEFSESGAASPQA CEEEECCCCCCCCCC | 32.31 | 27738172 | |
400 | Phosphorylation | FSESGAASPQAGHPP ECCCCCCCCCCCCCC | 19.60 | 21712547 | |
419 | Phosphorylation | ASTSVSSSTSSPAPW HCCCCCCCCCCCCCC | 25.46 | 21712547 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BBP_SCHPO !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BBP_SCHPO !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BBP_SCHPO !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
U2AF2_SCHPO | prp2 | physical | 10923022 | |
YC93_SCHPO | SPCC584.03c | genetic | 22681890 | |
GET1_SCHPO | get1 | genetic | 22681890 | |
SRP2_SCHPO | srp2 | genetic | 26302002 |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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