BAG1B_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BAG1B_SCHPO
• UniProt AC: O59739
• Protein Name: BAG family molecular chaperone regulator 1B
• Gene Name: bag102
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 206
• Protein Description: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release..
• Protein Sequence: MSFFTQLCSMDKKYWISLAVLSVTVLISALLKKRATETEDIVVVHYDGEKLNFVLRQPRLNMVSYTSFLRRVCNAFSVMPDKASLKLNGVTLKDGSLSDQNVQNGSELELELPKLSPAMQQIEAYIDELQQDLVPKIEAFCQSSPASAQDVQDLHTRLSETLLARMIKLDAVNVEDDPEARLKRKEAIRLSQQYLSKLDSTKNQNK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
144	Phosphorylation	IEAFCQSSPASAQDV HHHHHHCCCCCHHHH	9.90	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BAG1B_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BAG1B_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BAG1B_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HSP7M_SCHPO	ssc1	physical	24497846
RPN11_SCHPO	rpn11	physical	24497846
RPN1_SCHPO	mts4	physical	24497846

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-144, AND MASSSPECTROMETRY.
PubMed: 18257517