dbPTM

HSP7M_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HSP7M_SCHPO
UniProt AC	P22774
Protein Name	Heat shock 70 kDa protein, mitochondrial
Gene Name	ssp1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	674
Subcellular Localization	Mitochondrion. Nucleus . Probably found also in the nucleus.
Protein Description
Protein Sequence	MISSRFTNVVRSGLRFQSKGASFKIGASLHGSRMTARWNSNASGNEKVKGPVIGIDLGTTTSCLAIMEGQTPKVIANAEGTRTTPSVVAFTKDGERLVGVSAKRQAVINPENTFFATKRLIGRRFKEPEVQRDIKEVPYKIVEHSNGDAWLEARGKTYSPSQIGGFILSKMRETASTYLGKDVKNAVVTVPAYFNDSQRQATKAAGAIAGLNVLRVVNEPTAAALAYGLDKKNDAIVAVFDLGGGTFDISILELNNGVFEVRSTNGDTHLGGEDFDVALVRHIVETFKKNEGLDLSKDRLAVQRIREAAEKAKCELSSLSKTDISLPFITADATGPKHINMEISRAQFEKLVDPLVRRTIDPCKRALKDANLQTSEINEVILVGGMTRMPRVVETVKSIFKREPAKSVNPDEAVAIGAAIQGGVLSGHVKDLVLLDVTPLSLGIETLGGVFTRLINRNTTIPTRKSQVFSTAADGQTAVEIRVFQGERELVRDNKLIGNFQLTGIAPAPKGQPQIEVSFDVDADGIINVSARDKATNKDSSITVAGSSGLTDSEIEAMVADAEKYRASDMARKEAIENGNRAESVCTDIESNLDIHKDKLDQQAVEDLRSKITDLRETVAKVNAGDEGITSEDMKKKIDEIQQLSLKVFESVYKNQNQGNESSGDNSAPEGDKK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
157	Phosphorylation	WLEARGKTYSPSQIG CHHHCCCEECHHHHH	31.86	25720772
159	Phosphorylation	EARGKTYSPSQIGGF HHCCCEECHHHHHHH	24.25	25720772
161	Phosphorylation	RGKTYSPSQIGGFIL CCCEECHHHHHHHHH	28.61	25720772
344	Phosphorylation	KHINMEISRAQFEKL CCCCEEECHHHHHHH	14.30	28889911
584	Phosphorylation	ENGNRAESVCTDIES HCCCCHHHHHHHHHH	22.85	28889911
662	Phosphorylation	NQNQGNESSGDNSAP CCCCCCCCCCCCCCC	43.55	24763107
663	Phosphorylation	QNQGNESSGDNSAPE CCCCCCCCCCCCCCC	43.94	21712547
667	Phosphorylation	NESSGDNSAPEGDKK CCCCCCCCCCCCCCC	50.36	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HSP7M_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HSP7M_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HSP7M_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HSP7M_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HSP7M_SCHPO

Related Literatures of Post-Translational Modification