B3GT4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: B3GT4_HUMAN
• UniProt AC: O96024
• Protein Name: Beta-1,3-galactosyltransferase 4
• Gene Name: B3GALT4
• Organism: Homo sapiens (Human).
• Sequence Length: 378
• Subcellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein.
• Protein Description: Involved in GM1/GD1B/GA1 ganglioside biosynthesis..
• Protein Sequence: MQLRLFRRLLLAALLLVIVWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNQEACSGPGAPPFLLILVCTAPENLNQRNAIRASWGGLREARGLRVQTLFLLGEPNAQHPVWGSQGSDLASESAAQGDILQAAFQDSYRNLTLKTLSGLNWAEKHCPMARYVLKTDDDVYVNVPELVSELVLRGGRWGQWERSTEPQREAEQEGGQVLHSEEVPLLYLGRVHWRVNPSRTPGGRHRVSEEQWPHTWGPFPPYASGTGYVLSASAVQLILKVASRAPLLPLEDVFVGVSARRGGLAPTQCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVGGSDGERTAPFCSWFQGVLGILRCRAIAWLQS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
93	Phosphorylation	QRNAIRASWGGLREA HHHHHHHHHHHHHHH	19.19	24719451
149	N-linked_Glycosylation	AFQDSYRNLTLKTLS HHHHHHHHCHHHHHC	29.19	UniProtKB CARBOHYD
170	Phosphorylation	KHCPMARYVLKTDDD HHCCCCCEEEECCCC	10.70	22817900
179	Phosphorylation	LKTDDDVYVNVPELV EECCCCEEEEHHHHH	8.03	22817900
202	Phosphorylation	RWGQWERSTEPQREA CCCCCCCCCCCHHHH	26.13	29116813
203	Phosphorylation	WGQWERSTEPQREAE CCCCCCCCCCHHHHH	58.88	29116813
330	Phosphorylation	CYGKFLLTSHRLDPW HHHHHHHHCCCCCHH	25.32	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of B3GT4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of B3GT4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of B3GT4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DYL1_HUMAN	DYNLL1	physical	21900206
MET18_HUMAN	METTL18	physical	21900206
DAAM1_HUMAN	DAAM1	physical	21988832

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.