UniProt ID | ASHH1_ARATH | |
---|---|---|
UniProt AC | Q84WW6 | |
Protein Name | Histone-lysine N-methyltransferase ASHH1 {ECO:0000305} | |
Gene Name | ASHH1 | |
Organism | Arabidopsis thaliana (Mouse-ear cress). | |
Sequence Length | 492 | |
Subcellular Localization | Nucleus. Chromosome, centromere. Associates with centromeric constitutive heterochromatin.. | |
Protein Description | Histone methyltransferase involved in regulation of flowering time. Required for the expression of the SOC1/AGL20 gene. Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) at the SOC1 locus. Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus.. | |
Protein Sequence | MQFSCDPDQEGDELPQYEHIYQNDFSYRKHKKQKEEDISICECKFDFGDPDSACGERCLNVITNTECTPGYCPCGVYCKNQKFQKCEYAKTKLIKCEGRGWGLVALEEIKAGQFIMEYCGEVISWKEAKKRAQTYETHGVKDAYIISLNASEAIDATKKGSLARFINHSCRPNCETRKWNVLGEVRVGIFAKESISPRTELAYDYNFEWYGGAKVRCLCGAVACSGFLGAKSRGFQEDTYVWEDGDDRYSVDKIPVYDSAEDELTSEPSKNGESNTNEEKEKDISTENHLESTALNIQQQSDSTPTPMEEDVVTETVKTETSEDMKLLSQNSQEDSSPKTAIVSRVHGNISKIKSESLPKKRGRPFSGGKTKNVAQKHVDIANVVQLLATKEAQDEVLKYEEVKKEAAVRLSSLYDEIRPAIEEHERDSQDSVATSVAEKWIQASCNKLKAEFDLYSSVIKNIASTPIKPQDTKTKVAEAGNEDHIKLLEAK | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
194 | Phosphorylation | VGIFAKESISPRTEL EEEEECCCCCCCCEE | 27.88 | 19880383 | |
196 | Phosphorylation | IFAKESISPRTELAY EEECCCCCCCCEEEE | 20.01 | 19880383 | |
257 | Phosphorylation | SVDKIPVYDSAEDEL EEEEECCCCCCCCHH | 9.99 | 23776212 | |
259 | Phosphorylation | DKIPVYDSAEDELTS EEECCCCCCCCHHCC | 18.83 | 23776212 | |
332 | Phosphorylation | MKLLSQNSQEDSSPK HHHHHHCCCCCCCCC | 27.58 | 23776212 | |
336 | Phosphorylation | SQNSQEDSSPKTAIV HHCCCCCCCCCHHHH | 48.03 | 23776212 | |
337 | Phosphorylation | QNSQEDSSPKTAIVS HCCCCCCCCCHHHHE | 42.62 | 23776212 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ASHH1_ARATH !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ASHH1_ARATH !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ASHH1_ARATH !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
ASHH1_ARATH | SDG26 | physical | 22438063 | |
ASHH2_ARATH | EFS | physical | 22438063 | |
ATX1_ARATH | ATX1 | physical | 22438063 | |
H4_HUMAN | HIST1H4I | physical | 18070919 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
loading...