| UniProt ID | ASCL3_HUMAN | |
|---|---|---|
| UniProt AC | Q9NQ33 | |
| Protein Name | Achaete-scute homolog 3 | |
| Gene Name | ASCL3 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 180 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Transcriptional repressor. Inhibits myogenesis (By similarity).. | |
| Protein Sequence | MDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 87 | Phosphorylation | PNYRGCEYSYGPAFT CCCCCCHHCCCCCCC | 15.98 | 22210691 | |
| 88 | Phosphorylation | NYRGCEYSYGPAFTR CCCCCHHCCCCCCCC | 11.00 | 22210691 | |
| 89 | Phosphorylation | YRGCEYSYGPAFTRK CCCCHHCCCCCCCCC | 26.65 | 22210691 | |
| 140 | Phosphorylation | TLRAAIKYINYLQSL HHHHHHHHHHHHHHH | 6.57 | - | |
| 143 | Phosphorylation | AAIKYINYLQSLLYP HHHHHHHHHHHHHCC | 9.14 | - | |
| 163 | Phosphorylation | KNNPGKVSSMIATTS CCCCCCCCCEEEECC | 20.06 | 22115753 | |
| 164 | Phosphorylation | NNPGKVSSMIATTSH CCCCCCCCEEEECCC | 19.73 | 22115753 | |
| 165 | Phosphorylation | NPGKVSSMIATTSHH CCCCCCCEEEECCCC | 1.56 | - | |
| 168 | Phosphorylation | KVSSMIATTSHHADP CCCCEEEECCCCCCC | 20.22 | 22115753 | |
| 169 | Phosphorylation | VSSMIATTSHHADPM CCCEEEECCCCCCCC | 19.62 | 22115753 | |
| 170 | Phosphorylation | SSMIATTSHHADPMF CCEEEECCCCCCCCC | 14.66 | 22115753 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ASCL3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ASCL3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ASCL3_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ASCL3_HUMAN | ASCL3 | physical | 11784080 | |
| A4_HUMAN | APP | physical | 21832049 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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