ARMC9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARMC9_HUMAN
• UniProt AC: Q7Z3E5
• Protein Name: LisH domain-containing protein ARMC9
• Gene Name: ARMC9
• Organism: Homo sapiens (Human).
• Sequence Length: 818
• Protein Sequence: MGDILAHESELLGLVKEYLDFAEFEDTLKTFSKECKIKGKPLCKTVGGSFRDSKSLTIQKDLVAAFDNGDQKVFFDLWEEHISSSIRDGDSFAQKLEFYLHIHFAIYLLKYSVGRPDKEELDEKISYFKTYLETKGAALSQTTEFLPFYALPFVPNPMVHPSFKELFQDSWTPELKLKLIKFLALISKASNTPKLLTIYKENGQSNKEILQQLHQQLVEAERRSVTYLKRYNKIQADYHNLIGVTAELVDSLEATVSGKMITPEYLQSVCVRLFSNQMRQSLAHSVDFTRPGTASTMLRASLAPVKLKDVPLLPSLDYEKLKKDLILGSDRLKAFLLQALRWRLTTSHPGEQRETVLQAYISNDLLDCYSHNQRSVLQLLHSTSDVVRQYMARLINAFASLAEGRLYLAQNTKVLQMLEGRLKEEDKDIITRENVLGALQKFSLRRPLQTAMIQDGLIFWLVDVLKDPDCLSDYTLEYSVALLMNLCLRSTGKNMCAKVAGLVLKVLSDLLGHENHEIQPYVNGALYSILSVPSIREEARAMGMEDILRCFIKEGNAEMIRQIEFIIKQLNSEELPDGVLESDDDEDEDDEEDHDIMEADLDKDELIQPQLGELSGEKLLTTEYLGIMTNTGKTRRKGLANVQWSGDEPLQRPVTPGGHRNGYPVVEDQHTPPQTAQHARNGHPQALPAAHEAVYREGKPSTPESCVSSSSAIIAKPGEWLPRGRQEEPRPAPTGTPRQPREAPQDPGNGVTTRECASAFTCKPRAPCTPEMLDWNPPKAKASVLAPLFSSCGPQQASRPGSTASSTRGLPSSQSHRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	Ubiquitination	AEFEDTLKTFSKECK HHHHHHHHHHCHHCC	50.01	-
33	Ubiquitination	DTLKTFSKECKIKGK HHHHHHCHHCCCCCE	64.04	-
44	Ubiquitination	IKGKPLCKTVGGSFR CCCEECCEECCCCCC	54.66	-
49	Phosphorylation	LCKTVGGSFRDSKSL CCEECCCCCCCCCCC	15.92	29507054
53	Phosphorylation	VGGSFRDSKSLTIQK CCCCCCCCCCCEECE	21.64	29083192
54	Ubiquitination	GGSFRDSKSLTIQKD CCCCCCCCCCEECEE	54.49	-
55	Phosphorylation	GSFRDSKSLTIQKDL CCCCCCCCCEECEEE	34.40	29083192
57	Phosphorylation	FRDSKSLTIQKDLVA CCCCCCCEECEEEEE	28.58	29083192
60	Ubiquitination	SKSLTIQKDLVAAFD CCCCEECEEEEEHHC	49.53	-
107	Phosphorylation	LHIHFAIYLLKYSVG HHHHHHHHHHHHHCC	11.53	18083107
111	Phosphorylation	FAIYLLKYSVGRPDK HHHHHHHHHCCCCCH	14.46	29083192
112	Phosphorylation	AIYLLKYSVGRPDKE HHHHHHHHCCCCCHH	19.26	29083192
124	Ubiquitination	DKEELDEKISYFKTY CHHHHHHHHHHHHHH	36.30	-
126	Phosphorylation	EELDEKISYFKTYLE HHHHHHHHHHHHHHH	35.27	27461979
127	Phosphorylation	ELDEKISYFKTYLET HHHHHHHHHHHHHHH	16.74	27461979
129	Ubiquitination	DEKISYFKTYLETKG HHHHHHHHHHHHHCC	28.20	-
130	Phosphorylation	EKISYFKTYLETKGA HHHHHHHHHHHHCCC	24.36	27461979
131	Phosphorylation	KISYFKTYLETKGAA HHHHHHHHHHHCCCH	11.79	27461979
134	Phosphorylation	YFKTYLETKGAALSQ HHHHHHHHCCCHHHC	31.98	27461979
172	Phosphorylation	ELFQDSWTPELKLKL HHHCCCCCHHHHHHH	15.73	29083192
176	Ubiquitination	DSWTPELKLKLIKFL CCCCHHHHHHHHHHH	41.75	-
178	Acetylation	WTPELKLKLIKFLAL CCHHHHHHHHHHHHH	46.72	12835009
181	Acetylation	ELKLKLIKFLALISK HHHHHHHHHHHHHHH	44.77	12835013
187	Phosphorylation	IKFLALISKASNTPK HHHHHHHHHHCCCCC	24.02	26074081
188	Ubiquitination	KFLALISKASNTPKL HHHHHHHHHCCCCCE	49.17	-
190	Phosphorylation	LALISKASNTPKLLT HHHHHHHCCCCCEEE	45.00	26074081
192	Phosphorylation	LISKASNTPKLLTIY HHHHHCCCCCEEEEE	21.21	26074081
207	Ubiquitination	KENGQSNKEILQQLH HHCCCCHHHHHHHHH	51.91	-
229	Ubiquitination	RRSVTYLKRYNKIQA HHHHHHHHHHCCCCC	42.28	-
231	Phosphorylation	SVTYLKRYNKIQADY HHHHHHHHCCCCCCH	21.15	-
306	Ubiquitination	RASLAPVKLKDVPLL HHHHCCCCCCCCCCC	49.08	-
308	Ubiquitination	SLAPVKLKDVPLLPS HHCCCCCCCCCCCCC	51.46	-
315	Phosphorylation	KDVPLLPSLDYEKLK CCCCCCCCCCHHHHH	33.57	22468782
320	Ubiquitination	LPSLDYEKLKKDLIL CCCCCHHHHHHHHCC	60.42	-
407	Phosphorylation	SLAEGRLYLAQNTKV HHHHCCCHHHHHHHH	9.91	24719451
412	Phosphorylation	RLYLAQNTKVLQMLE CCHHHHHHHHHHHHH	15.50	24719451
413	Ubiquitination	LYLAQNTKVLQMLEG CHHHHHHHHHHHHHH	48.80	-
427	Ubiquitination	GRLKEEDKDIITREN HCCCHHHHCCCCHHH	54.85	-
441 (in isoform 2)	Ubiquitination	-	37.46	21890473
441 (in isoform 1)	Ubiquitination	-	37.46	21890473
441	Ubiquitination	NVLGALQKFSLRRPL HHHHHHHHHCCCCCH	37.46	21890473
443	Phosphorylation	LGALQKFSLRRPLQT HHHHHHHCCCCCHHH	28.18	25394399
531	Phosphorylation	GALYSILSVPSIREE HHHHHHHCCHHHHHH	30.25	21406692
534	Phosphorylation	YSILSVPSIREEARA HHHHCCHHHHHHHHH	31.93	21406692
553	Ubiquitination	DILRCFIKEGNAEMI HHHHHHHHCCCHHHH	39.04	-
572	Phosphorylation	FIIKQLNSEELPDGV HHHHHCCCCCCCCCC	40.83	21406692
582	Phosphorylation	LPDGVLESDDDEDED CCCCCCCCCCCCCCC	42.02	28625504
631	Phosphorylation	YLGIMTNTGKTRRKG HHHEECCCCCCCCCC	30.78	24173317
645	Phosphorylation	GLANVQWSGDEPLQR CCCCCCCCCCCCCCC	21.19	27966365
655	Phosphorylation	EPLQRPVTPGGHRNG CCCCCCCCCCCCCCC	20.92	27251275
663	Phosphorylation	PGGHRNGYPVVEDQH CCCCCCCCCCCCCCC	9.08	-
671	Phosphorylation	PVVEDQHTPPQTAQH CCCCCCCCCCCHHHH	30.91	28555341

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARMC9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARMC9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARMC9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
NPL4_HUMAN	NPLOC4	physical	22863883
PRPS2_HUMAN	PRPS2	physical	22863883
CKLF5_HUMAN	CMTM5	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.