ARL13_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARL13_CAEEL
• UniProt AC: H2L0N8
• Protein Name: ADP-ribosylation factor-like protein 13B
• Gene Name: arl-13
• Organism: Caenorhabditis elegans.
• Sequence Length: 370
• Subcellular Localization: Cell projection, cilium membrane ; Lipid-anchor . Associates to the cilium membrane via palmitoylation. Localizes to proximal ciliary membranes, to an inversin-like subciliary membrane compartment, excluding the transition zone.
• Protein Description: Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. Required for normal sensory cilium function. May act by maintaining the association between IFT subcomplexes A and B..
• Protein Sequence: MTEKSWFETIFCCCCHRTPIIRREIKLGCFGIGSAGKTTFLKVLKGEDPRDLLRTNGFSTVKMEYDETFHLTIYDVGGDKGIRGIWSNYYAEVHGIIYVIDYSTDETFTESIEALHSLTSNPHVQKKPIFLLLNNQNNREFDDVEISNETKIQAGQHKIVLFSHFNKYNGYLDNIKSATLTVMARAKKDRNEYQEQFVRFIDSISEHYVELSEGVKTAELALRIRQEEAKEQRRLMQMKVEHDALKADVAGLELRNQPPVQPPIPPDPPSDPKSASVHIEESPPMSLASSTIPSDIIQSTPETGTPRDPVNFCRISQTSTKPVSPESNSVKEEPTIILKDNYFLPPKAPGRQYSRIQRIQNVLNNRVVPK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	S-palmitoylation	SWFETIFCCCCHRTP CHHHHHHHHHHCCCH		20231383
13	S-palmitoylation	WFETIFCCCCHRTPI HHHHHHHHHHCCCHH		20231383
14	S-palmitoylation	FETIFCCCCHRTPII HHHHHHHHHCCCHHH		20231383
15	S-palmitoylation	ETIFCCCCHRTPIIR HHHHHHHHCCCHHHC		20231383
239	Sumoylation	QRRLMQMKVEHDALK HHHHHHHHHHHHHHH		23128241
331	Sumoylation	SPESNSVKEEPTIIL CCCCCCCCCCCEEEE		23128241

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARL13_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARL13_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARL13_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBC9_CAEEL	ubc-9	physical	23128241
MEL26_CAEEL	mel-26	physical	23128241
DIM_CAEEL	dim-1	physical	23128241
PSA7_CAEEL	pas-4	physical	23128241
RS4_CAEEL	rps-4	physical	23128241

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.