APRR3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: APRR3_ARATH
• UniProt AC: Q9LVG4
• Protein Name: Two-component response regulator-like APRR3
• Gene Name: APRR3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 495
• Subcellular Localization: Nucleus .
• Protein Description: Controls photoperiodic flowering response. Component of the circadian clock. Controls the degradation of APRR1/TOC1 by the SCF(ZTL) complex. Expression of several members of the ARR-like family is controlled by circadian rhythm. The particular coordinated sequential expression of APRR9, APRR7, APRR5, APRR3 and APPR1 result to circadian waves that may be at the basis of the endogenous circadian clock..
• Protein Sequence: MCFNNIETGDEVETERQVFGSSEEDEFRVEDTARNTNNVQISQQQQQPLAHVVKWERYLPVRSLKVLLVENDDSTRHIVTALLKNCSYEVTAVPDVLEAWRILEDEKSCIDLVLTEVDMPVHSGTGLLSKIMSHKTLKNIPVIMMSSHDSMVLVFKCLSNGAVDFLVKPIRKNELKNLWQHVWRRCHSSSGSGSESGIHDKKSVKPESTQGSENDASISDEHRNESGSSGGLSNQDGGSDNGSGTQSSWTKRASDTKSTSPSNQFPDAPNKKGTYENGCAHVNRLKEAEDQKEQIGTGSQTGMSMSKKAEEPGDLEKNAKYSVQALERNNDDTLNRSSGNSQVESKAPSSNREDLQSLEQTLKKTREDRDYKVGDRSVLRHSNLSAFSKYNNGATSAKKAPEENVESCSPHDSPIAKLLGSSSSSDNPLKQQSSGSDRWAQREAALMKFRLKRKERCFEKKVRYHSRKKLAEQRPHVKGQFIRKRDDHKSGSEDN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
337	Phosphorylation	NDDTLNRSSGNSQVE CCCCCCCCCCCHHHH	41.34	26091701
338	Phosphorylation	DDTLNRSSGNSQVES CCCCCCCCCCHHHHH	38.46	26091701
350	Phosphorylation	VESKAPSSNREDLQS HHHCCCCCCHHHHHH	38.56	26091701
357	Phosphorylation	SNREDLQSLEQTLKK CCHHHHHHHHHHHHH	40.97	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of APRR3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of APRR3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of APRR3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
APRR1_ARATH	TOC1	physical	18055606
WNK1_ARATH	WNK1	physical	12506983
WNK1_ARATH	WNK1	physical	12091722

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.