APBLB_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: APBLB_ARATH
• UniProt AC: Q9SUS3
• Protein Name: Beta-adaptin-like protein B
• Gene Name: BETAB-AD
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 894
• Subcellular Localization: Golgi apparatus. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Associated with the trans-Golgi network. Component of the coat surrounding the cytoplasmic fa
• Protein Description: Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity)..
• Protein Sequence: MSGHDSKYFSTTKKGEIPELKEELNSQYKDKRKDAVKKVIAAMTVGKDVSSLFTDVVNCMQTENLELKKLVYLYLINYAKSQPDLAILAVNTFVKDSQDPNPLIRALAVRTMGCIRVDKITEYLCDPLQKCLKDDDPYVRKTAAICVAKLFDINAELVEDRGFLEALKDLISDNNPMVVANAVAALAEIQENSSSPIFEINSTTLTKLLTALNECTEWGQVFILDALSKYKAADPREAENIVERVTPRLQHANCAVVLSAVKMILQQMELITSTDVIRNLCKKMAPPLVTLLSAEPEIQYVALRNINLIVQKRPTILAHEIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVLLEFKEYATEVDVDFVRKAVRAIGRCAIKLERAAERCISVLLELIKIKVNYVVQEAIIVIKDIFRRYPNTYESIIATLCESLDTLDEPEAKASMIWIIGEYAERIDNADELLESFLENFPEEPAQVQLQLLTATVKLFLKKPTEGPQQMIQVVLNNATVETDNPDLRDRAYIYWRLLSTDPEAAKDVVLAEKPVISDDSNQLDPSLLDELLTNISTLSSVYHKPPEAFVTRLKTTVQKTEDEDFAEGSEAGYSSSNPVDSAASPPGNIPQPSGRQPAPAVPAPVPDLLGDLMGLDNAAIVPVDDPITQSGPPLPVVVPASSGQGLQISAQLSRKDGQVFYSMLFENNSQSVLDGFMIQFNKNTFGLAAAGSLQIPPLHPATSARTMLPMVLFQNMSAGPPSSLLQVAVKNNQQPVWYFTDKIILHALFGEDGRMERGTFLETWRSLPDSNEVLKEFPGITITSVESTIELLTAFNMFFIAKRKNGNQDVIYLSAKDPRDVPFLIELTAMVGQPGLKCAVKTPTPEIAPLFFEALELLFKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MSGHDSKYFSTTK --CCCCCCCCCCCCC	24.47	25561503
593	Phosphorylation	LKTTVQKTEDEDFAE HHHCCEECCCCCCCC	31.42	23776212
602	Phosphorylation	DEDFAEGSEAGYSSS CCCCCCCCCCCCCCC	18.77	23776212
606	Phosphorylation	AEGSEAGYSSSNPVD CCCCCCCCCCCCCCC	16.66	23776212
607	Phosphorylation	EGSEAGYSSSNPVDS CCCCCCCCCCCCCCC	26.77	23776212
608	Phosphorylation	GSEAGYSSSNPVDSA CCCCCCCCCCCCCCC	26.17	23776212
609	Phosphorylation	SEAGYSSSNPVDSAA CCCCCCCCCCCCCCC	38.93	23776212
614	Phosphorylation	SSSNPVDSAASPPGN CCCCCCCCCCCCCCC	26.43	23776212
617	Phosphorylation	NPVDSAASPPGNIPQ CCCCCCCCCCCCCCC	31.20	23776212
626	Phosphorylation	PGNIPQPSGRQPAPA CCCCCCCCCCCCCCC	41.16	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of APBLB_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of APBLB_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of APBLB_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AP2A1_ARATH	alpha-ADR	physical	23975899
AP2S_ARATH	AT1G47830	physical	23975899
AP2M_ARATH	AT5G46630	physical	23975899
CLAH1_ARATH	AT3G11130	physical	23975899
CLC2_ARATH	AT2G40060	physical	23975899

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.