AI5L2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AI5L2_ARATH
• UniProt AC: Q9LES3
• Protein Name: ABSCISIC ACID-INSENSITIVE 5-like protein 2
• Gene Name: DPBF3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 297
• Subcellular Localization: Nucleus .
• Protein Description: Binds to the embryo specification element and the ABA-responsive element (ABRE) of the Dc3 gene promoter. Could participate in abscisic acid-regulated gene expression during seed development..
• Protein Sequence: MDSQRGIVEQAKSQSLNRQSSLYSLTLDEVQNHLGSSGKALGSMNLDELLKSVCSVEANQPSSMAVNGGAAAQEGLSRQGSLTLPRDLSKKTVDEVWKDIQQNKNGGSAHERRDKQPTLGEMTLEDLLLKAGVVTETIPGSNHDGPVGGGSAGSGAGLGQNITQVGPWIQYHQLPSMPQPQAFMPYPVSDMQAMVSQSSLMGGLSDTQTPGRKRVASGEVVEKTVERRQKRMIKNRESAARSRARKQAYTHELEIKVSRLEEENERLRKQKEVEKILPSVPPPDPKRQLRRTSSAPF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	GIVEQAKSQSLNRQS HHHHHHHHHCCCCCH	28.19	29654922
15	Phosphorylation	VEQAKSQSLNRQSSL HHHHHHHCCCCCHHH	34.40	29654922
21	Phosphorylation	QSLNRQSSLYSLTLD HCCCCCHHHEEEHHH	24.00	19880383
43	Phosphorylation	SSGKALGSMNLDELL CCCCCCCCCCHHHHH	12.83	30291188
44	Sulfoxidation	SGKALGSMNLDELLK CCCCCCCCCHHHHHH	5.68	23289948
77	Phosphorylation	AAAQEGLSRQGSLTL HHHHHCCCCCCCCCC	33.15	28011693
81	Phosphorylation	EGLSRQGSLTLPRDL HCCCCCCCCCCCCCC	15.16	30291188
83	Phosphorylation	LSRQGSLTLPRDLSK CCCCCCCCCCCCCCC	36.09	23776212
118	Phosphorylation	ERRDKQPTLGEMTLE CHHCCCCCCCCCCHH	44.92	30291188
123	Phosphorylation	QPTLGEMTLEDLLLK CCCCCCCCHHHHHHH	23.77	23776212
217	Phosphorylation	PGRKRVASGEVVEKT CCCCCCCCCCHHHHH	32.40	23111157
294	Phosphorylation	RQLRRTSSAPF---- HHHHHCCCCCC----	39.07	29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AI5L2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AI5L2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AI5L2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
14336_ARATH	GRF6	physical	21798944
14333_ARATH	GRF3	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-43, AND MASSSPECTROMETRY.
PubMed: 19376835