dbPTM

ABT1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ABT1_MOUSE
UniProt AC	Q9QYL7
Protein Name	Activator of basal transcription 1
Gene Name	Abt1
Organism	Mus musculus (Mouse).
Sequence Length	269
Subcellular Localization	Nucleus . Nucleus, nucleolus .
Protein Description	Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes..
Protein Sequence	MVKAGELVEQQKAAMEEEANAEAAEDQEEPEDTACSSSSKKKKKVVPGIVYLGHVPPRFRPLHVRNLLSAYGEVGRVFFQAEDHFVKRKKKAAAAAGGKKGAKYSKDYTEGWVEFRDKRVAKRVAASLHNTPMGARKRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLRNVEQGQHFLAADGDATRPNSSWTFTQRPTEQEFRARKAARPGGRERARLANVEDQARSNRGLLAKIFGAPLPAESKEKP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
91	Acetylation	HFVKRKKKAAAAAGG HHHHHHHHHHHHCCC	46.42	7304775
99	Acetylation	AAAAAGGKKGAKYSK HHHHCCCCCCCCCCC	47.30	7921113
100	Acetylation	AAAAGGKKGAKYSKD HHHCCCCCCCCCCCC	68.33	7708575
103	Acetylation	AGGKKGAKYSKDYTE CCCCCCCCCCCCCCC	59.74	19845177
106	Acetylation	KKGAKYSKDYTEGWV CCCCCCCCCCCCCCE	52.22	19845185
139	Phosphorylation	PMGARKRSPFRYDLW CCCCCCCCCCCHHCC	31.27	46157321

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ABT1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ABT1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ABT1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
TBP_HUMAN	TBP	physical	10648625
TBP_MOUSE	Tbp	physical	10648625

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ABT1_MOUSE

Related Literatures of Post-Translational Modification