ABD18_HUMAN - dbPTM
ABD18_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ABD18_HUMAN
UniProt AC Q0P651
Protein Name Protein ABHD18 {ECO:0000305}
Gene Name ABHD18 {ECO:0000312|HGNC:HGNC:26111}
Organism Homo sapiens (Human).
Sequence Length 414
Subcellular Localization Secreted .
Protein Description
Protein Sequence MGVSKLDILYRRLLLTKLFIRGWGRPEDLKRLFEFRKMIGNRERCQNLVSSDYPVHIDKIEEQSDCKILDGHFVSPMAHYVPDIMPIESVIARFQFIVPKEWNSKYRPVCIHLAGTGDHHYWRRRTLMARPMIKEARMASLLLENPYYGCRKPKDQVRSSLKNVSDLFVMGGALVLESAALLHWLEREGYGPLGMTGISMGGHMASLAVSNWPKPMPLIPCLSWSTASGVFTTTDSFKMGQEFVKHFTSSADKLTNLNLVSRTLNLDISNQVVSQKPADCHNSSKTSVSATSEGLLLQDTSKMKRFNQTLSTNKSGYTSRNPQSYHLLSKEQSRNSLRKESLIFMKGVMDECTHVANFSVPVDPSLIIVVQAKEDAYIPRTGVRSLQEIWPGCEIRYLEGGHISAYLFKQGLFR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
50PhosphorylationERCQNLVSSDYPVHI
HHHHHHHCCCCCCCH
30631047
51PhosphorylationRCQNLVSSDYPVHID
HHHHHHCCCCCCCHH
30631047
84 (in isoform 4)Ubiquitination-21890473
160 (in isoform 3)Ubiquitination-21890473
171 (in isoform 2)Ubiquitination-21890473
206PhosphorylationSMGGHMASLAVSNWP
ECCCHHHHHHHCCCC
26552605
210PhosphorylationHMASLAVSNWPKPMP
HHHHHHHCCCCCCCC
26552605
253UbiquitinationHFTSSADKLTNLNLV
HHHCCHHHHHCCCHH
21890473
253 (in isoform 1)Ubiquitination-21890473
255PhosphorylationTSSADKLTNLNLVSR
HCCHHHHHCCCHHEE
22186101
276UbiquitinationSNQVVSQKPADCHNS
CCCCCCCCCCCCCCC
-
282N-linked_GlycosylationQKPADCHNSSKTSVS
CCCCCCCCCCCCCCC
UniProtKB CARBOHYD
284PhosphorylationPADCHNSSKTSVSAT
CCCCCCCCCCCCCCC
22186109
307N-linked_GlycosylationTSKMKRFNQTLSTNK
HHHHHHHHHCCCCCC
UniProtKB CARBOHYD
314UbiquitinationNQTLSTNKSGYTSRN
HHCCCCCCCCCCCCC
-
317PhosphorylationLSTNKSGYTSRNPQS
CCCCCCCCCCCCHHH
17053785
330UbiquitinationQSYHLLSKEQSRNSL
HHHHCCCHHHHHHHH
-
397PhosphorylationWPGCEIRYLEGGHIS
CCCCEEEEEECCCHH
73680439
404PhosphorylationYLEGGHISAYLFKQG
EEECCCHHEEEECCC
22673903
406PhosphorylationEGGHISAYLFKQGLF
ECCCHHEEEECCCCC
22673903

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ABD18_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ABD18_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ABD18_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SELO_HUMANSELOphysical
26186194
SELO_HUMANSELOphysical
28514442
CH60_HUMANHSPD1physical
28514442
MGT5B_HUMANMGAT5Bphysical
28514442
LAMP2_HUMANLAMP2physical
28514442
TOIP2_HUMANTOR1AIP2physical
28514442
IFG15_HUMANTOR1AIP2physical
28514442

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ABD18_HUMAN

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Related Literatures of Post-Translational Modification

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