| UniProt ID | ABD18_HUMAN | |
|---|---|---|
| UniProt AC | Q0P651 | |
| Protein Name | Protein ABHD18 {ECO:0000305} | |
| Gene Name | ABHD18 {ECO:0000312|HGNC:HGNC:26111} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 414 | |
| Subcellular Localization | Secreted . | |
| Protein Description | ||
| Protein Sequence | MGVSKLDILYRRLLLTKLFIRGWGRPEDLKRLFEFRKMIGNRERCQNLVSSDYPVHIDKIEEQSDCKILDGHFVSPMAHYVPDIMPIESVIARFQFIVPKEWNSKYRPVCIHLAGTGDHHYWRRRTLMARPMIKEARMASLLLENPYYGCRKPKDQVRSSLKNVSDLFVMGGALVLESAALLHWLEREGYGPLGMTGISMGGHMASLAVSNWPKPMPLIPCLSWSTASGVFTTTDSFKMGQEFVKHFTSSADKLTNLNLVSRTLNLDISNQVVSQKPADCHNSSKTSVSATSEGLLLQDTSKMKRFNQTLSTNKSGYTSRNPQSYHLLSKEQSRNSLRKESLIFMKGVMDECTHVANFSVPVDPSLIIVVQAKEDAYIPRTGVRSLQEIWPGCEIRYLEGGHISAYLFKQGLFR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 50 | Phosphorylation | ERCQNLVSSDYPVHI HHHHHHHCCCCCCCH | 30631047 | ||
| 51 | Phosphorylation | RCQNLVSSDYPVHID HHHHHHCCCCCCCHH | 30631047 | ||
| 84 (in isoform 4) | Ubiquitination | - | 21890473 | ||
| 160 (in isoform 3) | Ubiquitination | - | 21890473 | ||
| 171 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 206 | Phosphorylation | SMGGHMASLAVSNWP ECCCHHHHHHHCCCC | 26552605 | ||
| 210 | Phosphorylation | HMASLAVSNWPKPMP HHHHHHHCCCCCCCC | 26552605 | ||
| 253 | Ubiquitination | HFTSSADKLTNLNLV HHHCCHHHHHCCCHH | 21890473 | ||
| 253 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 255 | Phosphorylation | TSSADKLTNLNLVSR HCCHHHHHCCCHHEE | 22186101 | ||
| 276 | Ubiquitination | SNQVVSQKPADCHNS CCCCCCCCCCCCCCC | - | ||
| 282 | N-linked_Glycosylation | QKPADCHNSSKTSVS CCCCCCCCCCCCCCC | UniProtKB CARBOHYD | ||
| 284 | Phosphorylation | PADCHNSSKTSVSAT CCCCCCCCCCCCCCC | 22186109 | ||
| 307 | N-linked_Glycosylation | TSKMKRFNQTLSTNK HHHHHHHHHCCCCCC | UniProtKB CARBOHYD | ||
| 314 | Ubiquitination | NQTLSTNKSGYTSRN HHCCCCCCCCCCCCC | - | ||
| 317 | Phosphorylation | LSTNKSGYTSRNPQS CCCCCCCCCCCCHHH | 17053785 | ||
| 330 | Ubiquitination | QSYHLLSKEQSRNSL HHHHCCCHHHHHHHH | - | ||
| 397 | Phosphorylation | WPGCEIRYLEGGHIS CCCCEEEEEECCCHH | 73680439 | ||
| 404 | Phosphorylation | YLEGGHISAYLFKQG EEECCCHHEEEECCC | 22673903 | ||
| 406 | Phosphorylation | EGGHISAYLFKQGLF ECCCHHEEEECCCCC | 22673903 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ABD18_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ABD18_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ABD18_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SELO_HUMAN | SELO | physical | 26186194 | |
| SELO_HUMAN | SELO | physical | 28514442 | |
| CH60_HUMAN | HSPD1 | physical | 28514442 | |
| MGT5B_HUMAN | MGAT5B | physical | 28514442 | |
| LAMP2_HUMAN | LAMP2 | physical | 28514442 | |
| TOIP2_HUMAN | TOR1AIP2 | physical | 28514442 | |
| IFG15_HUMAN | TOR1AIP2 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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