dbPTM

2A5B_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	2A5B_ARATH
UniProt AC	O04376
Protein Name	Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform
Gene Name	B'BETA
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	499
Subcellular Localization	Nucleus . Cytoplasm .
Protein Description	The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that positively regulates brassinosteroid signaling by dephosphorylating and activating BZR1. [PubMed: 21258370]
Protein Sequence	MFKKIMKGGHRKPSKSEANEPSSYGIGLPDNRSGPGSNVVVSHASRGALVNSSPSPVTATPPPPPLGSVEPLPLFRDVPVSERQTLFLRKLQNCCFLFDFTDTIKNARDKEIKRQTLLELVDFIQSGSSKISESCQEEMIKMISVNIFRSLPPASHENTGQEPADPEEEEPYLEPSWPHLQLVYELLLRYVVSTDTDTKVAKRYIDHSFVLKLLDLFDSEDPREREYLKTILHRIYGKFMVHRPFIRKAINNIFYRFIYETERHSGIGELLEILGSIINGFALPMKEEHKLFLIRVLIPLHKPKPIVVYHQQLSYCIVQFVEKDYKLADTVIRGLLKYWPVTNCSKENLFLGELEEVLEATQPVEFQRCMVPLFQQIGRCLTSSHFQVAERALFLWNNEHIVGLIAQNRSVILPIIYPTLEKNIQSHWNQAVHGLTTNIKKMFMEMDPELFEECQRQYEEKQAKSKEVEEQRQYTWKRLAEAAAERDGGGGEEDHMITS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of 2A5B_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of 2A5B_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of 2A5B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of 2A5B_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
2AAA_ARATH	RCN1	physical	10091592
BZR1_ARATH	BZR1	physical	21258370
BZR2_ARATH	BES1	physical	21258370

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of 2A5B_ARATH

Related Literatures of Post-Translational Modification