ZSC9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSC9_HUMAN
• UniProt AC: O15535
• Protein Name: Zinc finger and SCAN domain-containing protein 9
• Gene Name: ZSCAN9
• Organism: Homo sapiens (Human).
• Sequence Length: 394
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MNTNSKEVLSLGVQVPEAWEELLTMKVEAKSHLQWQESRLKRSNPLAREIFRRHFRQLCYQETPGPREALTRLQELCYQWLRPHVSTKEQILDLLVLEQFLSILPKELQGWVREHCPESGEEAVILLEDLERELDEPQHEMVAHRHRQEVLCKEMVPLAEQTPLTLQSQPKEPQLTCDSAQKCHSIGETDEVTKTEDRELVLRKDCPKIVEPHGKMFNEQTWEVSQQDPSHGEVGEHKDRIERQWGNLLGEGQHKCDECGKSFTQSSGLIRHQRIHTGERPYECNECGKAFSRSSGLFNHRGIHNIQKRYHCKECGKVFSQSAGLIQHQRIHKGEKPYQCSQCSKSYSRRSFLIEHQRSHTGERPHQCIECGKSFNRHCNLIRHQKIHTVAELV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Sumoylation	WEELLTMKVEAKSHL HHHHHHCHHHHHHHH		28112733
30	Ubiquitination	LTMKVEAKSHLQWQE HHCHHHHHHHHHHHH		-
215	Sumoylation	KIVEPHGKMFNEQTW CCCCCCCHHHCCCCE		28112733
221	Phosphorylation	GKMFNEQTWEVSQQD CHHHCCCCEEECCCC		-
225	Phosphorylation	NEQTWEVSQQDPSHG CCCCEEECCCCCCCC		-
230	Phosphorylation	EVSQQDPSHGEVGEH EECCCCCCCCCCCCC		-
238	Sumoylation	HGEVGEHKDRIERQW CCCCCCCHHHHHHHH		28112733
277	Phosphorylation	IRHQRIHTGERPYEC CCCCEEECCCCCCCC		28348404
346	Phosphorylation	QCSQCSKSYSRRSFL CCCCCCCCCCCCCHH		24719451
351	Phosphorylation	SKSYSRRSFLIEHQR CCCCCCCCHHHHHCH		24719451
397	Phosphorylation	VAELV---------- HHHCC----------		24719451
402	Phosphorylation	--------------- ---------------		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSC9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSC9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSC9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZN446_HUMAN	ZNF446	physical	16189514
ANM6_HUMAN	PRMT6	physical	23455924
SUV91_HUMAN	SUV39H1	physical	23455924
MAGH1_HUMAN	MAGEH1	physical	25416956
ZN446_HUMAN	ZNF446	physical	25416956
ZNF24_HUMAN	ZNF24	physical	26186194
TFF3_HUMAN	TFF3	physical	20499178

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.