ZNF70_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZNF70_HUMAN
• UniProt AC: Q9UC06
• Protein Name: Zinc finger protein 70
• Gene Name: ZNF70
• Organism: Homo sapiens (Human).
• Sequence Length: 446
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MEVPPATKFGETFAFENRLESQQGLFPGEDLGDPFLQERGLEQMAVIYKEIPLGEQDEENDDYEGNFSLCSSPVQHQSIPPGTRPQDDELFGQTFLQKSDLSMCQIIHSEEPSPCDCAETDRGDSGPNAPHRTPQPAKPYACRECGKAFSQSSHLLRHLVIHTGEKPYECCECGKAFSQSSHLLRHQIIHTGEKPYECRECGKAFRQSSALTQHQKIHTGKRPYECRECGKDFSRSSSLRKHERIHTGERPYQCKECGKSFNQSSGLSQHRKIHTLKKPHECDLCGKAFCHRSHLIRHQRIHTGKKPYKCDECGKAFSQSSNLIEHRKTHTGEKPYKCQKCGKAFSQSSSLIEHQRIHTGEKPYECCQCGKAFCHSSALIQHQRIHTGKKPYTCECGKAFRHRSALIEHYKTHTREKPYVCNLCGKSFRGSSHLIRHQKIHSGEKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	AFENRLESQQGLFPG CCCCHHHHCCCCCCC	32.18	24719451
48	Phosphorylation	LEQMAVIYKEIPLGE HHHHHHEEEECCCCC	8.93	28152594
109	Phosphorylation	SMCQIIHSEEPSPCD CCEEEEECCCCCCCC	32.99	-
150	Phosphorylation	RECGKAFSQSSHLLR HHHHHHHHHHHHHHH	33.73	28555341
152	Phosphorylation	CGKAFSQSSHLLRHL HHHHHHHHHHHHHHH	20.66	-
153	Phosphorylation	GKAFSQSSHLLRHLV HHHHHHHHHHHHHHH	15.54	-
163	Phosphorylation	LRHLVIHTGEKPYEC HHHHHHCCCCCCCCC	35.59	30576142
178	Phosphorylation	CECGKAFSQSSHLLR CCCCHHHHCCHHHHH	33.73	28555341
191	Phosphorylation	LRHQIIHTGEKPYEC HHHCEEECCCCCCCH	36.31	29214152
208	Phosphorylation	CGKAFRQSSALTQHQ HHHHHHHHCHHHHHH	17.21	28555341
212	Phosphorylation	FRQSSALTQHQKIHT HHHHCHHHHHHHHHC	24.58	29083192
219	Phosphorylation	TQHQKIHTGKRPYEC HHHHHHHCCCCCCCH	48.12	29083192
236	Phosphorylation	CGKDFSRSSSLRKHE CCCCCCCCHHHCCCC	24.07	-
247	Phosphorylation	RKHERIHTGERPYQC CCCCCCCCCCCCCCH	38.06	27732954
328	Ubiquitination	SNLIEHRKTHTGEKP CCHHHHCCCCCCCCC	46.71	-
329	Phosphorylation	NLIEHRKTHTGEKPY CHHHHCCCCCCCCCC	25.32	28348404
331	Phosphorylation	IEHRKTHTGEKPYKC HHHCCCCCCCCCCCC	52.87	24719451
334	Ubiquitination	RKTHTGEKPYKCQKC CCCCCCCCCCCCCCC	55.80	-
359	Phosphorylation	IEHQRIHTGEKPYEC HHHCCCCCCCCCCCC	44.67	28111955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZNF70_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZNF70_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZNF70_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZF64A_HUMAN	ZFP64	physical	20211142
ZF64B_HUMAN	ZFP64	physical	20211142

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.