ZNF69_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZNF69_HUMAN
• UniProt AC: Q9UC07
• Protein Name: Zinc finger protein 69
• Gene Name: ZNF69
• Organism: Homo sapiens (Human).
• Sequence Length: 566
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MPCCSHRRCREDPGTSESQEMDPVAFDDVAVNFTQEEWALLDISQRKLYKEVMLETFRNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKPCKCQQPKKAFRYHPSFRTPQRDHTGEKPYACKECGKTFISHSSIQRHVVMHSGDGPYKCKFCGKAFHCLSLYLIHERIHTGEKPYECKQCGKSFSYSATLRIHERTHTGEKPYECQQCGKAFHSPRCYRRHERIHTGEKAYQCKECGKAFTCPQYVRIHERTHSRKKPYECTQCGKALSSLTSFQTHIRMHSGERPYECKICGKGFCSANSFQRHEKTHSGEKPYKCKQCGKAFIHSSSLRYHERIHTGEKPYECKQCGKAFRSSSHLQLHGRTHTGEKPYECQECGKAFRSMKNLQSHERTQTHVRIHSGERPYKCKLCGKGFYCPKSLQRHEKTHTGEKLYECKQCGEAFSSSSSFRYHERTHTGEKPYKCKQCGKAFRAASVLRMHGRTHPEDKPYECKQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
71	Phosphorylation	GKSWKDQNIEYEYQN CHHHHHCCCEEEECC	38.91	24719451
85	Phosphorylation	NPRRNFRSLIEKKVN CCCHHHHHHHHHHHH	29.57	24719451
106	Phosphorylation	HCGETFTQVPDDRLN CCCCCCCCCCCHHCC	40.32	24719451
120	Phosphorylation	NFQEKKASPEIKSCD CCCHHCCCCCCCCCC	31.76	24719451
159	Phosphorylation	KAYEYQEYGPKPCKC CCEECHHHCCCCCCC	24.17	-
200	Phosphorylation	ACKECGKTFISHSSI ECCHHCCEEECHHHC	16.10	30622161
243	Phosphorylation	LIHERIHTGEKPYEC HHHHHHCCCCCCEEC	44.67	29496963
251	Sumoylation	GEKPYECKQCGKSFS CCCCEECCCCCCEEE	36.36	-
269	Phosphorylation	TLRIHERTHTGEKPY EEEEECCCCCCCCCE	22.32	-
271	Phosphorylation	RIHERTHTGEKPYEC EEECCCCCCCCCEEC	46.56	-
325	Phosphorylation	YVRIHERTHSRKKPY HHEECCCCCCCCCCE	22.63	29449344
327	Phosphorylation	RIHERTHSRKKPYEC EECCCCCCCCCCEEE	45.22	29449344
342	Phosphorylation	TQCGKALSSLTSFQT CHHHHHHHHCHHHHH	28.32	27732954
343	Phosphorylation	QCGKALSSLTSFQTH HHHHHHHHCHHHHHH	36.19	27732954
345	Phosphorylation	GKALSSLTSFQTHIR HHHHHHCHHHHHHCC	29.46	27732954
346	Phosphorylation	KALSSLTSFQTHIRM HHHHHCHHHHHHCCC	22.20	27732954
411	Phosphorylation	RYHERIHTGEKPYEC CCHHCCCCCCCCCCC	44.67	29496963
419	Sumoylation	GEKPYECKQCGKAFR CCCCCCCCCCCCCHH	36.36	-
437	Phosphorylation	HLQLHGRTHTGEKPY CEEECCCCCCCCCCC	28.51	-
439	Phosphorylation	QLHGRTHTGEKPYEC EECCCCCCCCCCCCH	46.56	-
527	Phosphorylation	SFRYHERTHTGEKPY CCCEECCCCCCCCCE	22.32	28348404
529	Phosphorylation	RYHERTHTGEKPYKC CEECCCCCCCCCEEC	46.56	26270265
534	Phosphorylation	THTGEKPYKCKQCGK CCCCCCCEECCHHHH	39.83	29438985

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZNF69_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZNF69_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZNF69_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KATL1_HUMAN	KATNAL1	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.