ZN844_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN844_HUMAN
• UniProt AC: Q08AG5
• Protein Name: Zinc finger protein 844
• Gene Name: ZNF844
• Organism: Homo sapiens (Human).
• Sequence Length: 666
• Subcellular Localization: Nucleus.
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MDLVAFEDVAVNFTQEEWSLLDPSQKNLYREVMQETLRNLASIGEKWKDQNIEDQYKNPRNNLRSLLGERVDENTEENHCGETSSQIPDDTLNKKTSPGVKSCESSVCGEVFVGHSSLNRHIRADTAHKPSEYQEYGQEPYKCQQRKKAFRCHPSFQMQEKAHTGEKLYDCKECGKTFISHSSIQRHMIMHNGDGTYKCKFCGKACPCLSIYLIHERVHTGEKPYKCKQCGKAFSYSTSLQIHERTHTGEKPYECKECGKAFGSPNSLYEHRRTHTGEKPYECKQCGKAFRWFHSFQIHERTHSEEKAYECTKCGKAFKCPSYLCRHEVTHSGKKPCECKQCGKALSYLNFQRHMKMHTRMRPYKCKTVEKPLILPVRFEDMKELTLERNLMNASTVVKPSIVPVPFTIMKGLTLERNPMNVSSVVKPSFLPLPFDIMKGLTLERNRMSVSNVGKPSDLPHTFKCMEGLTLKRNPMNVSSVVKPSFFPLPFDIMKGLTLERNPMSVSNVGKPSHLPHTFKCMKGLTLESNCMNLNNVKKPLDLSETFKFMKRHTLERNPIRNMEKHSTISLPFKYMQQCTEDRMPMNVKSVTKHSYLPRSFEYMQEHTLERNPMNVRNAEKRSIIFLLCVYTKGCTLERNHINVRIVGKHSVCLVPFVDIKGLTLE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
177	Phosphorylation	DCKECGKTFISHSSI EHHHHCCEEECCHHH	16.10	30622161
220	Phosphorylation	LIHERVHTGEKPYKC EEECCCCCCCCCEEC	44.15	29496963
223	Sumoylation	ERVHTGEKPYKCKQC CCCCCCCCCEECCCC	55.80	-
223	Ubiquitination	ERVHTGEKPYKCKQC CCCCCCCCCEECCCC	55.80	-
223	Sumoylation	ERVHTGEKPYKCKQC CCCCCCCCCEECCCC	55.80	-
246	Phosphorylation	SLQIHERTHTGEKPY EEEEECCCCCCCCCE	22.32	29396449
248	Phosphorylation	QIHERTHTGEKPYEC EEECCCCCCCCCEEC	46.56	29496963
251	Ubiquitination	ERTHTGEKPYECKEC CCCCCCCCCEECCHH	55.00	-
253	Phosphorylation	THTGEKPYECKECGK CCCCCCCEECCHHHH	45.05	26074081
256	Ubiquitination	GEKPYECKECGKAFG CCCCEECCHHHHHHC	44.06	-
256	Sumoylation	GEKPYECKECGKAFG CCCCEECCHHHHHHC	44.06	-
256	Sumoylation	GEKPYECKECGKAFG CCCCEECCHHHHHHC	44.06	-
264	Phosphorylation	ECGKAFGSPNSLYEH HHHHHHCCCCHHHCC	17.91	26074081
267	Phosphorylation	KAFGSPNSLYEHRRT HHHCCCCHHHCCCCC	35.39	26074081
269	Phosphorylation	FGSPNSLYEHRRTHT HCCCCHHHCCCCCCC	14.98	26074081
274	Phosphorylation	SLYEHRRTHTGEKPY HHHCCCCCCCCCCCC	24.60	29396449
276	Phosphorylation	YEHRRTHTGEKPYEC HCCCCCCCCCCCCCC	46.56	29496963
279	Ubiquitination	RRTHTGEKPYECKQC CCCCCCCCCCCCCCC	55.00	-
284	Sumoylation	GEKPYECKQCGKAFR CCCCCCCCCCCCHHH	36.36	-
284	Sumoylation	GEKPYECKQCGKAFR CCCCCCCCCCCCHHH	36.36	-
330	Phosphorylation	YLCRHEVTHSGKKPC HHHHCCCCCCCCCCE	13.82	-
386	Phosphorylation	FEDMKELTLERNLMN HHHHHHHHHHHHCCC	27.88	26074081
395	Phosphorylation	ERNLMNASTVVKPSI HHHCCCCCCCCCCCC	19.41	26074081
396	Phosphorylation	RNLMNASTVVKPSIV HHCCCCCCCCCCCCC	27.23	26074081
401	Phosphorylation	ASTVVKPSIVPVPFT CCCCCCCCCCCCCEE	30.42	26074081
408	Phosphorylation	SIVPVPFTIMKGLTL CCCCCCEEEECCCCC	17.68	26074081
414	Phosphorylation	FTIMKGLTLERNPMN EEEECCCCCCCCCCC	34.93	-
580	Phosphorylation	FKYMQQCTEDRMPMN HHHHHHHCCCCCCCC	36.26	28509920
595	Phosphorylation	VKSVTKHSYLPRSFE HHHHHCCCCCCCCHH	29.89	22210691
596	Phosphorylation	KSVTKHSYLPRSFEY HHHHCCCCCCCCHHH	22.05	22210691
608	Phosphorylation	FEYMQEHTLERNPMN HHHHHHHCCCCCCCC	29.57	22210691
617	Methylation	ERNPMNVRNAEKRSI CCCCCCCCCHHHHCE	31.47	115920669

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN844_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN844_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN844_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KR109_HUMAN	KRTAP10-9	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.