ZN679_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN679_HUMAN
• UniProt AC: Q8IYX0
• Protein Name: Zinc finger protein 679
• Gene Name: ZNF679
• Organism: Homo sapiens (Human).
• Sequence Length: 411
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAKRPGSPGSREMGLLTFRDVVIEFSLEEWQCLDHAQQNLYRDVMLENYRNLVSLGIAVSKPDLITCLEQNKEPWNIKRNEMVTKHPVMCSHFTQDLPPELGIKDSLQKVIPRRYGKSGHDNLQVKTCKSMGECEVQKGGCNEVNQCLSTTQNKIFQTHKCVKVFGKFSNSNRHKTRHTGKKHFKCKKYGKSFCMVSQLHQHQIIHTRENSYQCEECGKPFNCSSTLSKHKRIHTGEKPYRCEECGKAFTWSSTLTKHRRIHTGEKPYTCEECGQAFSRSSTLANHKRIHTGEKPYTCEECGKAFSLSSSLTYHKRIHTGEKPYTCEECGKAFNCSSTLKKHKIIHTGEKPYKCKECGKAFAFSSTLNTHKRIHTGEEPYKCEECDKAFKWSSSLANHKSMHTGEKPYKCE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
85	Acetylation	KRNEMVTKHPVMCSH CCCCCCCCCCEECCC	34.20	18586751
106	Phosphorylation	PELGIKDSLQKVIPR HHHCCCHHHHHHHCH	27.91	25002506
109	Ubiquitination	GIKDSLQKVIPRRYG CCCHHHHHHHCHHHC	47.64	-
169	Phosphorylation	VKVFGKFSNSNRHKT HHHEEECCCCCCCCC	42.72	26552605
171	Phosphorylation	VFGKFSNSNRHKTRH HEEECCCCCCCCCCC	33.76	26552605
176	Phosphorylation	SNSNRHKTRHTGKKH CCCCCCCCCCCCCCC	22.89	26552605
226	Phosphorylation	KPFNCSSTLSKHKRI CCCCCCCCCCCCCCC	20.82	-
235	Phosphorylation	SKHKRIHTGEKPYRC CCCCCCCCCCCCEEC	44.67	29496963
238	Sumoylation	KRIHTGEKPYRCEEC CCCCCCCCCEECCCC	49.01	-
238	Ubiquitination	KRIHTGEKPYRCEEC CCCCCCCCCEECCCC	49.01	-
238	Sumoylation	KRIHTGEKPYRCEEC CCCCCCCCCEECCCC	49.01	-
263	Phosphorylation	TKHRRIHTGEKPYTC CCCCCCCCCCCCCCH	44.67	28111955
268	Phosphorylation	IHTGEKPYTCEECGQ CCCCCCCCCHHHHHH	34.78	-
291	Phosphorylation	ANHKRIHTGEKPYTC CCCCCEECCCCCEEH	44.67	28111955
319	Phosphorylation	TYHKRIHTGEKPYTC EEECCCCCCCCCEEH	44.67	28111955
343	Ubiquitination	SSTLKKHKIIHTGEK CHHHHCCCEEECCCC	52.84	-
347	Phosphorylation	KKHKIIHTGEKPYKC HCCCEEECCCCCEEC	36.31	29496963
350	Ubiquitination	KIIHTGEKPYKCKEC CEEECCCCCEECCCC	55.80	22505724
352	Phosphorylation	IHTGEKPYKCKECGK EECCCCCEECCCCCC	39.83	-
375	Phosphorylation	NTHKRIHTGEEPYKC CCCCCCCCCCCCCCC	43.87	-
381	Sumoylation	HTGEEPYKCEECDKA CCCCCCCCCCHHCHH	45.98	-
381	Sumoylation	HTGEEPYKCEECDKA CCCCCCCCCCHHCHH	45.98	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN679_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN679_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN679_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KR103_HUMAN	KRTAP10-3	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.