ZN394_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN394_HUMAN
• UniProt AC: Q53GI3
• Protein Name: Zinc finger protein 394
• Gene Name: ZNF394
• Organism: Homo sapiens (Human).
• Sequence Length: 561
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MNSSLTAQRRGSDAELGPWVMAARSKDAAPSQRDGLLPVKVEEDSPGSWEPNYPAASPDPETSRLHFRQLRYQEVAGPEEALSRLRELCRRWLRPELLSKEQILELLVLEQFLTILPEELQAWVREHCPESGEEAVAVVRALQRALDGTSSQGMVTFEDTAVSLTWEEWERLDPARRDFCRESAQKDSGSTVPPSLESRVENKELIPMQQILEEAEPQGQLQEAFQGKRPLFSKCGSTHEDRVEKQSGDPLPLKLENSPEAEGLNSISDVNKNGSIEGEDSKNNELQNSARCSNLVLCQHIPKAERPTDSEEHGNKCKQSFHMVTWHVLKPHKSDSGDSFHHSSLFETQRQLHEERPYKCGNCGKSFKQRSDLFRHQRIHTGEKPYGCQECGKSFSQSAALTKHQRTHTGEKPYTCLKCGERFRQNSHLNRHQSTHSRDKHFKCEECGETCHISNLFRHQRLHKGERPYKCEECEKSFKQRSDLFKHHRIHTGEKPYGCSVCGKRFNQSATLIKHQRIHTGEKPYKCLECGERFRQSTHLIRHQRIHQNKVLSAGRGGSRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MNSSLTAQRR -----CCCCCCCHHC	25.98	28509920
12	Phosphorylation	LTAQRRGSDAELGPW CCCHHCCCCCCHHHH	31.66	25159151
40	Sumoylation	RDGLLPVKVEEDSPG CCCCCCEEEECCCCC	41.82	28112733
72	Phosphorylation	LHFRQLRYQEVAGPE HHHHHHHHHHHHCHH	20.02	-
83	Phosphorylation	AGPEEALSRLRELCR HCHHHHHHHHHHHHH	36.00	-
203	Sumoylation	LESRVENKELIPMQQ HHHHHCCCCCCCHHH	40.15	28112733
228	Sumoylation	LQEAFQGKRPLFSKC HHHHHCCCCCCHHHC	39.81	28112733
233	Phosphorylation	QGKRPLFSKCGSTHE CCCCCCHHHCCCCHH	34.42	24719451
237	Phosphorylation	PLFSKCGSTHEDRVE CCHHHCCCCHHHHHH	35.74	28348404
238	Phosphorylation	LFSKCGSTHEDRVEK CHHHCCCCHHHHHHH	17.99	28348404
247	Phosphorylation	EDRVEKQSGDPLPLK HHHHHHHCCCCCCCC	57.12	-
254	Sumoylation	SGDPLPLKLENSPEA CCCCCCCCCCCCCCC	52.38	28112733
258	Phosphorylation	LPLKLENSPEAEGLN CCCCCCCCCCCCCCC	18.10	22199227
266	Phosphorylation	PEAEGLNSISDVNKN CCCCCCCCCCCCCCC	28.63	28102081
268	Phosphorylation	AEGLNSISDVNKNGS CCCCCCCCCCCCCCC	35.01	28102081
282	Sumoylation	SIEGEDSKNNELQNS CCCCCCCCCCHHCHH	75.91	-
282	Sumoylation	SIEGEDSKNNELQNS CCCCCCCCCCHHCHH	75.91	28112733
292	S-nitrosylation	ELQNSARCSNLVLCQ HHCHHHHHCCEEEEE	2.94	24105792
298	S-nitrosylation	RCSNLVLCQHIPKAE HHCCEEEEECCCCCC	1.84	24105792
371	Phosphorylation	GKSFKQRSDLFRHQR CCCHHHHHHHHHCCC	35.85	21712546
381	Phosphorylation	FRHQRIHTGEKPYGC HHCCCCCCCCCCCCC	44.67	28111955
403	Ubiquitination	SQSAALTKHQRTHTG CHHHHHHHHCCCCCC	38.29	-
407	Phosphorylation	ALTKHQRTHTGEKPY HHHHHCCCCCCCCCE	19.74	-
409	Phosphorylation	TKHQRTHTGEKPYTC HHHCCCCCCCCCEEE	46.56	-
443	Sumoylation	HSRDKHFKCEECGET CCCCCCCCHHHCCCC	40.22	28112733
486	Methylation	KQRSDLFKHHRIHTG HHHHHHHHCCCCCCC	45.88	115978233
492	Phosphorylation	FKHHRIHTGEKPYGC HHCCCCCCCCCCCCC	44.67	28111955
520	Phosphorylation	IKHQRIHTGEKPYKC EECCCCCCCCCCEEE	44.67	29496963
537	Phosphorylation	CGERFRQSTHLIRHQ CHHHHHHHHHHHHCH	17.34	-
538	Phosphorylation	GERFRQSTHLIRHQR HHHHHHHHHHHHCHH	16.62	-
556	Methylation	NKVLSAGRGGSRL-- HCCCCCCCCCCCC--	46.12	115920485

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN394_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN394_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN394_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CTBL1_HUMAN	CTNNBL1	physical	28514442
SCND1_HUMAN	SCAND1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.