ZN343_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN343_HUMAN
• UniProt AC: Q6P1L6
• Protein Name: Zinc finger protein 343
• Gene Name: ZNF343
• Organism: Homo sapiens (Human).
• Sequence Length: 599
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MMLPYPSALGDQYWEEILLPKNGENVETMKKLTQNHKAKGLPSNDTDCPQKKEGKAQIVVPVTFRDVTVIFTEAEWKRLSPEQRNLYKEVMLENYRNLLSLAEPKPEIYTCSSCLLAFSCQQFLSQHVLQIFLGLCAENHFHPGNSSPGHWKQQGQQYSHVSCWFENAEGQERGGGSKPWSARTEERETSRAFPSPLQRQSASPRKGNMVVETEPSSAQRPNPVQLDKGLKELETLRFGAINCREYEPDHNLESNFITNPRTLLGKKPYICSDCGRSFKDRSTLIRHHRIHSMEKPYVCSECGRGFSQKSNLSRHQRTHSEEKPYLCRECGQSFRSKSILNRHQWTHSEEKPYVCSECGRGFSEKSSFIRHQRTHSGEKPYVCLECGRSFCDKSTLRKHQRIHSGEKPYVCRECGRGFSQNSDLIKHQRTHLDEKPYVCRECGRGFCDKSTLIIHERTHSGEKPYVCGECGRGFSRKSLLLVHQRTHSGEKHYVCRECRRGFSQKSNLIRHQRTHSNEKPYICRECGRGFCDKSTLIVHERTHSGEKPYVCSECGRGFSRKSLLLVHQRTHSGEKHYVCRECGRGFSHKSNLIRHQRTH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
181	Phosphorylation	GGGSKPWSARTEERE CCCCCCCCCCCCHHH	19.19	24114839
216	Phosphorylation	MVVETEPSSAQRPNP EEEECCCCCCCCCCC	31.88	28555341
231	Ubiquitination	VQLDKGLKELETLRF CCCCCHHHHHHHHEE	69.76	-
300	Phosphorylation	MEKPYVCSECGRGFS CCCCEEECCCCCCCC	26.36	30631047
310	Phosphorylation	GRGFSQKSNLSRHQR CCCCCCCCCCCHHCC	35.05	22798277
313	Phosphorylation	FSQKSNLSRHQRTHS CCCCCCCCHHCCCCC	31.78	-
323	Sumoylation	QRTHSEEKPYLCREC CCCCCCCCCHHHHHH	34.61	-
323	Sumoylation	QRTHSEEKPYLCREC CCCCCCCCCHHHHHH	34.61	-
325	Phosphorylation	THSEEKPYLCRECGQ CCCCCCCHHHHHHCC	29.51	26657352
346	Phosphorylation	ILNRHQWTHSEEKPY HHHCCCCCCCCCCCE	14.68	26657352
348	Phosphorylation	NRHQWTHSEEKPYVC HCCCCCCCCCCCEEE	39.82	26657352
351	Sumoylation	QWTHSEEKPYVCSEC CCCCCCCCCEEECCC	37.28	-
351	Sumoylation	QWTHSEEKPYVCSEC CCCCCCCCCEEECCC	37.28	-
367	Phosphorylation	RGFSEKSSFIRHQRT CCCCCCHHHHCCCCC	35.44	24719451
404	Phosphorylation	RKHQRIHSGEKPYVC HHHCCCCCCCCCEEC	46.40	30631047
435	Sumoylation	QRTHLDEKPYVCREC HHHCCCCCCEECCCC	41.12	-
435	Sumoylation	QRTHLDEKPYVCREC HHHCCCCCCEECCCC	41.12	28112733
506	Phosphorylation	RRGFSQKSNLIRHQR HCCCCHHHHHHHHCC	29.27	24719451
514	Phosphorylation	NLIRHQRTHSNEKPY HHHHHCCCCCCCCCE	24.08	24719451
519	Sumoylation	QRTHSNEKPYICREC CCCCCCCCCEEECCC	47.58	-
519	Sumoylation	QRTHSNEKPYICREC CCCCCCCCCEEECCC	47.58	-
534	Phosphorylation	GRGFCDKSTLIVHER CCCCCCCCEEEEEEC	18.39	-
535	Phosphorylation	RGFCDKSTLIVHERT CCCCCCCEEEEEECC	26.67	30576142
542	Phosphorylation	TLIVHERTHSGEKPY EEEEEECCCCCCCCE	19.87	30576142

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN343_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN343_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN343_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.