ZN177_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN177_HUMAN
• UniProt AC: Q13360
• Protein Name: Zinc finger protein 177
• Gene Name: ZNF177
• Organism: Homo sapiens (Human).
• Sequence Length: 481
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAAGWLTTWSQNSVTFQEVAVDFSQEEWALLDPAQKNLYKDVMLENFRNLASVGYQLCRHSLISKVDQEQLKTDERGILQGDCADWETQLKPKDTIAMQNIPGGKTSNGINTAENQPGEHSLECNHCGKFRKNTRFICTRYCKGEKCYKYIKYSKVFNHPSTLRSHVSIHIGEKTLEFTDCRKAFNQESSLRKHLRTPTGQKFQEYEQCDMSFSLHSSCSVREQIPTGEKGDECSDYGKISPLSVHTKTGSVEEGLECNEHEKTFTDPLSLQNCVRTHSGEMPYECSDCGKAFIFQSSLKKHMRSHTGEKPYECDHCGKSFSQSSHLNVHKRTHTGEKPYDCKECGKAFTVPSSLQKHVRTHTGEKPYECSDCGKAFIDQSSLKKHTRSHTGEKPYECNQCGKSFSTGSYLIVHKRTHTGEKTYECKECGKAFRNSSCLRVHVRTHTGEKPYKCIQCEKAFSTSTNLIMHKRIHNGQKLHE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	Phosphorylation	GYQLCRHSLISKVDQ HHHHHHHHHHHHCCH	14.19	24719451
161	Phosphorylation	SKVFNHPSTLRSHVS HEECCCCHHHHHEEE	9.80	-
162	Phosphorylation	KVFNHPSTLRSHVSI EECCCCHHHHHEEEE	35.92	-
189	Phosphorylation	RKAFNQESSLRKHLR HHHHCCHHHHHHHCC	8.90	26434776
190	Phosphorylation	KAFNQESSLRKHLRT HHHCCHHHHHHHCCC	36.05	26434776
324	Phosphorylation	CGKSFSQSSHLNVHK CCCCCCCCCCCEECC		22617229
325	Phosphorylation	GKSFSQSSHLNVHKR CCCCCCCCCCEECCC		22617229
333	Phosphorylation	HLNVHKRTHTGEKPY CCEECCCCCCCCCCC		-
335	Phosphorylation	NVHKRTHTGEKPYDC EECCCCCCCCCCCCC		21857030
350	Phosphorylation	KECGKAFTVPSSLQK CCCCCEEECCHHHHH		-
361	Phosphorylation	SLQKHVRTHTGEKPY HHHHHHHHCCCCCCE		-
363	Phosphorylation	QKHVRTHTGEKPYEC HHHHHHCCCCCCEEC		21857030
417	Phosphorylation	YLIVHKRTHTGEKTY EEEEEEECCCCCCEE		-
419	Phosphorylation	IVHKRTHTGEKTYEC EEEEECCCCCCEEEE		-
445	Phosphorylation	CLRVHVRTHTGEKPY EEEEEEEECCCCCCE		29083192
447	Phosphorylation	RVHVRTHTGEKPYKC EEEEEECCCCCCEEE		29083192
450	Ubiquitination	VRTHTGEKPYKCIQC EEECCCCCCEEEEEC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN177_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN177_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN177_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RHG21_HUMAN	ARHGAP21	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.