ZFR2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZFR2_HUMAN
• UniProt AC: Q9UPR6
• Protein Name: Zinc finger RNA-binding protein 2
• Gene Name: ZFR2
• Organism: Homo sapiens (Human).
• Sequence Length: 939
• Protein Sequence: MATSQYFDFAQGGGPQYSAQPPTLPLPTVGASYTAQPTPGMDPAVNPAFPPAAPAGYGGYQPHSGQDFAYGSRPQEPVPTATTMATYQDSYSYGQSAAARSYEDRPYFQSAALQSGRMTAADSGQPGTQEACGQPSPHGSHSHAQPPQQAPIVESGQPASTLSSGYTYPTATGVQPESSASIVTSYPPPSYNPTCTAYTAPSYPNYDASVYSAASPFYPPAQPPPPPGPPQQLPPPPAPAGSGSSPRADSKPPLPSKLPRPKAGPRQLQLHYCDICKISCAGPQTYREHLGGQKHRKKEAAQKTGVQPNGSPRGVQAQLHCDLCAVSCTGADAYAAHIRGSKHQKVFKLHAKLGKPIPTLEPALATESPPGAEAKPTSPTGPSVCASSRPALAKRPVASKALCEGPPEPQAAGCRPQWGKPAQPKLEGPGAPTQGGSKEAPAGCSDAQPVGPEYVEEVFSDEGRVLRFHCKLCECSFNDLNAKDLHVRGRRHRLQYRKKVNPDLPIATEPSSRARKVLEERMRKQRHLAEERLEQLRRWHAERRRLEEEPPQDVPPHAPPDWAQPLLMGRPESPASAPLQPGRRPASSDDRHVMCKHATIYPTEQELLAVQRAVSHAERALKLVSDTLAEEDRGRREEEGDKRSSVAPQTRVLKGVMRVGILAKGLLLRGDRNVRLALLCSEKPTHSLLRRIAQQLPRQLQMVTEDEYEVSSDPEANIVISSCEEPRMQVTISVTSPLMREDPSTDPGVEEPQADAGDVLSPKKCLESLAALRHARWFQARASGLQPCVIVIRVLRDLCRRVPTWGALPAWAMELLVEKAVSSAAGPLGPGDAVRRVLECVATGTLLTDGPGLQDPCERDQTDALEPMTLQEREDVTASAQHALRMLAFRQTHKVLGMDLLPPRHRLGARFRKRQRGPGEGEEGAGEKKRGRRGGEGLV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
256	Phosphorylation	DSKPPLPSKLPRPKA CCCCCCCCCCCCCCC	55.28	24719451
279	Phosphorylation	YCDICKISCAGPQTY ECCEEEEECCCCHHH	5.38	28152594
285	Phosphorylation	ISCAGPQTYREHLGG EECCCCHHHHHHHCC	27.90	28152594
286	Phosphorylation	SCAGPQTYREHLGGQ ECCCCHHHHHHHCCH	14.57	28152594
615	Phosphorylation	LAVQRAVSHAERALK HHHHHHHHHHHHHHH	18.92	22496350
644	Phosphorylation	EEEGDKRSSVAPQTR CCCCCCCCCCCCHHH	34.60	22817900
645	Phosphorylation	EEGDKRSSVAPQTRV CCCCCCCCCCCHHHH	26.74	22817900
650	Phosphorylation	RSSVAPQTRVLKGVM CCCCCCHHHHHCHHH	22.99	22817900
687	Phosphorylation	CSEKPTHSLLRRIAQ CCCCCCHHHHHHHHH	31.42	24719451
731	Phosphorylation	EEPRMQVTISVTSPL CCCCEEEEEEECCCC	7.22	24667141
733	Phosphorylation	PRMQVTISVTSPLMR CCEEEEEEECCCCCC	15.24	24667141
761	Phosphorylation	ADAGDVLSPKKCLES CCCCCCCCHHHHHHH	34.22	22817900
822	Phosphorylation	LLVEKAVSSAAGPLG HHHHHHHHHCCCCCC	21.08	26074081
823	Phosphorylation	LVEKAVSSAAGPLGP HHHHHHHHCCCCCCH	18.62	26074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZFR2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZFR2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZFR2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ILF2_HUMAN	ILF2	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.