ZF69B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZF69B_HUMAN
• UniProt AC: Q9UJL9
• Protein Name: Zinc finger protein ZFP69B
• Gene Name: ZFP69B
• Organism: Homo sapiens (Human).
• Sequence Length: 534
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MLQQLLITLPTEASTWVKLRHPKAATERVALWEDVTKMFKAEALLSQDADETQGESLESRVTLGSLTAESQELLTFKDVSVDFTQEEWGQLAPAHRNLYREVMLENYGNLVSVGCQLSKPGVISQLEKGEEPWLMERDISGVPSSDLKSKTKTKESALQNDISWEELHCGLMMERFTKGSSMYSTLGRISKCNKLESQQENQRMGKGQIPLMCKKTFTQERGQESNRFEKRINVKSEVMPGPIGLPRKRDRKYDTPGKRSRYNIDLVNHSRSYTKMKTFECNICEKIFKQLIHLTEHMRIHTGEKPFRCKECGKAFSQSSSLIPHQRIHTGEKPYECKECGKTFRHPSSLTQHVRIHTGEKPYECRVCEKAFSQSIGLIQHLRTHVREKPFTCKDCGKAFFQIRHLRQHEIIHTGVKPYICNVCSKTFSHSTYLTQHQRTHTGERPYKCKECGKAFSQRIHLSIHQRVHTGVKPYECSHCGKAFRHDSSFAKHQRIHTGEKPYDCNECGKAFSCSSSLIRHCKTHLRNTFSNVV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MLQQLLITLPTEAST CCCEEEEECCCCCCH		22468782
11	Phosphorylation	QLLITLPTEASTWVK EEEEECCCCCCHHHC		22468782
14	Phosphorylation	ITLPTEASTWVKLRH EECCCCCCHHHCCCC		24043423
15	Phosphorylation	TLPTEASTWVKLRHP ECCCCCCHHHCCCCC		24043423
36	Phosphorylation	VALWEDVTKMFKAEA HHHHHHHHHHHHHHH		-
37	Sumoylation	ALWEDVTKMFKAEAL HHHHHHHHHHHHHHH		28112733
40	Sumoylation	EDVTKMFKAEALLSQ HHHHHHHHHHHHHCC		28112733
118	Phosphorylation	VSVGCQLSKPGVISQ EEEECEECCCCCCCC		26503514
140	Phosphorylation	WLMERDISGVPSSDL EECEECCCCCCHHHH		23532336
144	Phosphorylation	RDISGVPSSDLKSKT ECCCCCCHHHHCCCC		23401153
149	Phosphorylation	VPSSDLKSKTKTKES CCHHHHCCCCCCHHH		23401153
151	Phosphorylation	SSDLKSKTKTKESAL HHHHCCCCCCHHHHH		29083192
178	Sumoylation	LMMERFTKGSSMYST HHHHHHCCCCHHHHH		28112733
191	Ubiquitination	STLGRISKCNKLESQ HHHHHHHHHCHHHHH		-
194	Ubiquitination	GRISKCNKLESQQEN HHHHHHCHHHHHHHH		-
235	Sumoylation	FEKRINVKSEVMPGP HHHHHCCCCCCCCCC		28112733
235	Sumoylation	FEKRINVKSEVMPGP HHHHHCCCCCCCCCC		-
262	Phosphorylation	TPGKRSRYNIDLVNH CCCCCCCCCEECCCC		29759185
270	Phosphorylation	NIDLVNHSRSYTKMK CEECCCCCCCCCCCC		29083192
272	Phosphorylation	DLVNHSRSYTKMKTF ECCCCCCCCCCCCCC		29083192
273	Phosphorylation	LVNHSRSYTKMKTFE CCCCCCCCCCCCCCC		29759185
274	Phosphorylation	VNHSRSYTKMKTFEC CCCCCCCCCCCCCCC		29759185
302	Phosphorylation	TEHMRIHTGEKPFRC HHCCCCCCCCCCEEC		29496963
330	Phosphorylation	IPHQRIHTGEKPYEC CCCCCCCCCCCCEEC		29496963
338	Sumoylation	GEKPYECKECGKTFR CCCCEECCCCCCCCC		-
338	Sumoylation	GEKPYECKECGKTFR CCCCEECCCCCCCCC		-
358	Phosphorylation	TQHVRIHTGEKPYEC CCEEEEECCCCCCCC		28111955
498	Phosphorylation	AKHQRIHTGEKPYDC CCCCCCCCCCCCCCC		28111955
516	Phosphorylation	GKAFSCSSSLIRHCK CCCEECCHHHHHHHH		24719451
517	Phosphorylation	KAFSCSSSLIRHCKT CCEECCHHHHHHHHH		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZF69B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZF69B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZF69B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
K1C40_HUMAN	KRT40	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.