ZBT7C_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZBT7C_MOUSE
• UniProt AC: Q8VCZ7
• Protein Name: Zinc finger and BTB domain-containing protein 7C
• Gene Name: Zbtb7c
• Organism: Mus musculus (Mouse).
• Sequence Length: 619
• Protein Description: May be a tumor suppressor gene..
• Protein Sequence: MANDIDELIGIPFPNHSSEVLCSLNEQRHAGLLCDVLLVVQEQEYRTHRSVLAACSKYFKKLFTAGSLASQPYVYEIDFVQPEALAAILEFAYTSTLTITASNVKHILNAARMLEIQCIVNVCLEIMEPGGSVGEEDDKEEEDEDDDDEDEDDEEEEEEEEEEEEDDPEDFADQENLPDPQDITCPQSPSKTDHLTEKDYSDTPRDFPDSFQPGSPGHLGVIRDFSIESLLRENLYPKANIPDRRPSLSPFAPEFFPHLWPGGFGAFAQLPEQPMDSGPLDLVIKNRKIKEEDKEELAPPPPPPFSSDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGSLFPPWPLVEERKLKPKASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCSICEVRFTRQDKLKIHMRKHTGERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRGRKPAAWRAASLLFGPGGPSADKAAFVMPPALGDVGGHLGGTAVCLPGPSPAKHFLASPKGTLSLQELERQFEETQMKLFGRAQLEAERNAGGLLALALAENVAATRPYFPLPDPWAAGLAGLPGLTGLNHVASMSEANN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
215	Phosphorylation	PDSFQPGSPGHLGVI CCCCCCCCCCCCEEE	34.10	27180971
288	Sumoylation	DLVIKNRKIKEEDKE CEEEECCCCCHHHHH	68.47	28289178
290	Sumoylation	VIKNRKIKEEDKEEL EEECCCCCHHHHHHH	59.07	28289178
537	Phosphorylation	PAKHFLASPKGTLSL HHHHHHCCCCCCCCH	29.32	25338131
554	Phosphorylation	LERQFEETQMKLFGR HHHHHHHHHHHHHHH	27.11	25338131

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZBT7C_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZBT7C_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZBT7C_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRBP1_MOUSE	Srebf1	physical	22331133
P53_MOUSE	Trp53	physical	22253232
MK08_MOUSE	Mapk8	physical	27646874

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.