ZBT45_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZBT45_HUMAN
• UniProt AC: Q96K62
• Protein Name: Zinc finger and BTB domain-containing protein 45
• Gene Name: ZBTB45
• Organism: Homo sapiens (Human).
• Sequence Length: 511
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity)..
• Protein Sequence: MAAAEAVHHIHLQNFSRSLLETLNGQRLGGHFCDVTVRIREASLRAHRCVLAAGSPFFQDKLLLGHSEIRVPPVVPAQTVRQLVEFLYSGSLVVAQGEALQVLTAASVLRIQTVIDECTQIIARARAPGTSAPTPLPTPVPPPLAPAQLRHRLRHLLAARPPGHPGAAHSRKQRQPARLQLPAPPTPAKAEGPDADPSLSAAPDDRGDEDDEESDDETDGEDGEGGGPGEGQAPPSFPDCAAGFLTAAADSACEEPPAPTGLADYSGAGRDFLRGAGSAEDVFPDSYVSTWHDEDGAVPEGCPTETPVQPDCILSGSRPPGVKTPGPPVALFPFHLGAPGPPAPPPSAPSGPAPAPPPAFYPTLQPEAAPSTQLGEVPAPSAAPTTAPSGTPARTPGAEPPTYECSHCRKTFSSRKNYTKHMFIHSGEKPHQCAVCWRSFSLRDYLLKHMVTHTGVRAFQCAVCAKRFTQKSSLNVHMRTHRPERAPCPACGKVFSHRALLERHLAAHPAP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
134	Phosphorylation	APGTSAPTPLPTPVP CCCCCCCCCCCCCCC	36.85	27251275
186	Phosphorylation	LQLPAPPTPAKAEGP CCCCCCCCCCCCCCC	34.52	21815630
402	Phosphorylation	TPGAEPPTYECSHCR CCCCCCCCCCCCCCC	42.54	-
411	Phosphorylation	ECSHCRKTFSSRKNY CCCCCCCCCCCCCCC	14.92	-
413	Phosphorylation	SHCRKTFSSRKNYTK CCCCCCCCCCCCCEE	34.17	-
414	Phosphorylation	HCRKTFSSRKNYTKH CCCCCCCCCCCCEEE	42.98	-
426	Phosphorylation	TKHMFIHSGEKPHQC EEEEEEECCCCCCEE	43.78	29449344
439	Phosphorylation	QCAVCWRSFSLRDYL EEEEEECCCCHHHHH	8.49	24719451
441	Phosphorylation	AVCWRSFSLRDYLLK EEEECCCCHHHHHHH	24.60	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZBT45_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZBT45_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZBT45_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MED31_HUMAN	MED31	physical	16169070

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.