ZBT22_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZBT22_MOUSE
• UniProt AC: Q9Z0G7
• Protein Name: Zinc finger and BTB domain-containing protein 22
• Gene Name: Zbtb22
• Organism: Mus musculus (Mouse).
• Sequence Length: 638
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MEPSALSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSAATTTTVTTAAAPSVSVPCASVPSGNGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDFSSTSQDAFVASAAGSGNRRDGGPVFPAPVVGSAGTTSGKLLLEADELCDDGGDGRGAVAPGAGLRRSNCMPASAVPQKHWVYVKQARNCPAPASLVHQDPDLEDEEEEEDLVLTCEDDEDEEMGGGSGVPAGGEPEATLSISDVRTLTEPADKGEEQVNFCESSNDFGPYEGGGAGAGLDDPGGPTPSSYALTHPPRPLLPLDVPGNQILVFPSSSSQAPGQPPGNTAEHGAVTLGGTSAVGLGIPSGSGGAPGGTGNSDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRMGVGGVGSGPGPGPGPGTPSGPALQPKRESSTVGGGSGDEANSATPPSHRRVWSPPSVHKVEMDFSGGGGAAH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
199	Phosphorylation	SHTSSRASENQSPSS CCCCCCCCCCCCCCC	35.65	28833060
203	Phosphorylation	SRASENQSPSSSNYF CCCCCCCCCCCCCCC	38.03	25521595
205	Phosphorylation	ASENQSPSSSNYFSP CCCCCCCCCCCCCCC	52.20	28833060
206	Phosphorylation	SENQSPSSSNYFSPR CCCCCCCCCCCCCCC	26.45	28066266
207	Phosphorylation	ENQSPSSSNYFSPRE CCCCCCCCCCCCCCC	39.63	28066266
209	Phosphorylation	QSPSSSNYFSPREST CCCCCCCCCCCCCCC	13.84	28066266
211	Phosphorylation	PSSSNYFSPRESTDF CCCCCCCCCCCCCCC	16.82	28833060
215	Phosphorylation	NYFSPRESTDFSSTS CCCCCCCCCCCCCCC	34.26	28285833
221	Phosphorylation	ESTDFSSTSQDAFVA CCCCCCCCCCCEEHH	29.25	28285833
583	Phosphorylation	GPGPGPGTPSGPALQ CCCCCCCCCCCCCCC	19.88	29514104
595	Phosphorylation	ALQPKRESSTVGGGS CCCCCCCCCCCCCCC	35.03	29895711
596	Phosphorylation	LQPKRESSTVGGGSG CCCCCCCCCCCCCCC	23.51	26160508
597	Phosphorylation	QPKRESSTVGGGSGD CCCCCCCCCCCCCCC	32.23	29895711
602	Phosphorylation	SSTVGGGSGDEANSA CCCCCCCCCCCCCCC	46.47	25521595
608	Phosphorylation	GSGDEANSATPPSHR CCCCCCCCCCCCCCC	40.33	26239621
610	Phosphorylation	GDEANSATPPSHRRV CCCCCCCCCCCCCCC	35.24	25521595
613	Phosphorylation	ANSATPPSHRRVWSP CCCCCCCCCCCCCCC	30.72	26160508
619	Phosphorylation	PSHRRVWSPPSVHKV CCCCCCCCCCCEEEE	24.87	26643407
622	Phosphorylation	RRVWSPPSVHKVEMD CCCCCCCCEEEEEEC	39.99	26643407

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZBT22_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZBT22_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZBT22_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZBT22_MOUSE	Zbtb22	physical	20211142
MED16_MOUSE	Med16	physical	20211142

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.