dbPTM

YCG2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YCG2_SCHPO
UniProt AC	O74447
Protein Name	Uncharacterized protein C16C4.02c
Gene Name	SPCC16C4.02c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	548
Subcellular Localization
Protein Description
Protein Sequence	MHIPHFHLHKGPKGVRTISYEQLLSEDDSYASEKLSEDHVTEVHFVTDKDEDSNASGESRGSMELLENCFSLLHAQDDTSKFVSLTMLAKLLNDHPNLIFKCWERMDMKFLDRLLLSTHYEYVDLGVSILLAFCSEEAILRSYEVKKRVSTLLQCCLKHYDLCIPVICTLSSNPKSAKYLLYYTSFIINEFPFEQAFEILSNALYALDNVQTYMRPIFQGIDKRRGWKLDCTFSFFSDLFSRFPVQSWYSEAIRANLQPLMDAVVERFITDKNLSSATVILSNLLKAAGPASIMPNDGFMILVIGRCSAEIRGSLGMLVKAVGQKGKHGTVSYTVCECYEVLGLLIRYLCENCDVLAQRIEPDKFFQLQRSLTELFSDTMDFLRDAWDNNKNRDNLASHVTVISAVATLCLWLTEDDSQYAQASGLMDIFVYLWRHSWSNGIDYAKWISVALPSMLSNKVFFKAFKDFDAWKVVYDDFIKCNDDLKGDKSFNDYILSTNEEDGEDERLAQAIQDFHILIQLNSLVPQSIWNDDIWQEPYWKNLLESNF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	KGPKGVRTISYEQLL CCCCCCEEECHHHHC	16.33	25720772
19	Phosphorylation	PKGVRTISYEQLLSE CCCCEEECHHHHCCC	23.23	28889911
25	Phosphorylation	ISYEQLLSEDDSYAS ECHHHHCCCCCCCCC	47.79	28889911
29	Phosphorylation	QLLSEDDSYASEKLS HHCCCCCCCCCHHCC	34.61	21712547
32	Phosphorylation	SEDDSYASEKLSEDH CCCCCCCCHHCCCCC	27.34	21712547
36	Phosphorylation	SYASEKLSEDHVTEV CCCCHHCCCCCCEEE	52.63	21712547
41	Phosphorylation	KLSEDHVTEVHFVTD HCCCCCCEEEEEEEC	28.95	21712547
47	Phosphorylation	VTEVHFVTDKDEDSN CEEEEEEECCCCCCC	36.07	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YCG2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YCG2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YCG2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ECL1_SCHPO	ecl1	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YCG2_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19; SER-25 AND THR-47,AND MASS SPECTROMETRY.	18257517 [Abstract]