dbPTM

YBEG_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YBEG_SCHPO
UniProt AC	Q9P775
Protein Name	Uncharacterized WD repeat-containing protein C17D11.16
Gene Name	SPBC1711.16
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	516
Subcellular Localization	Cytoplasm . Nucleus, nucleolus .
Protein Description
Protein Sequence	MSIVSSVAFVPRGYASEFPKSYDIDEIEYERINQLSKLKLEDARADLQSSMEDSNKANGNGEETTDGAEGVLQTSEEVDDELKVYNLDTYDDDEEEAETEGPAAMFSNIRGLAYHENGEKDPYITIDPQEQDDLEREEMQILPTDSLLLAARTEDNLSHVEVYVYEPTEENLYVHHDFLLPTFPLCLEWLDYKVGTSDNAPGNYVAVGTFDPEIEIWDLDIIDAVYPAAVLGAGASQVNKKKKKSKKINDSYHTDAVLALSSNRNAHNLLVSGSADTTLKLWDLSTCNCVKSFTYHSDKVSCLDWYSKAPSVLLSGSYDKTAKIADLRLEEAPSSFQVTSDVENVAWDQHSENNFFIGTDNGIVYYCDARNLSKSVWQLQAHDGPISCLSVNPSVPSFVATGSTDRVVKLWNTSDSSPKMVVSRDLDVGRVFTCSFTTDESTAFHLAASGSKGVVRVWDTATNPGVRKAFESRVTEEVTKKERIVQLEDRGAGEDSSDDDDYEDIEDDDDQDAEMS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSIVSSVAF ------CCCCCEEEE	31.53	29996109
21	Phosphorylation	YASEFPKSYDIDEIE CHHCCCCCCCCCHHH	28.42	28889911
22	Phosphorylation	ASEFPKSYDIDEIEY HHCCCCCCCCCHHHH	24.04	25720772
49	Phosphorylation	DARADLQSSMEDSNK HHHHHHHHHHHHHHC	38.66	24763107
496	Phosphorylation	DRGAGEDSSDDDDYE CCCCCCCCCCCCCCC	31.22	28889911
497	Phosphorylation	RGAGEDSSDDDDYED CCCCCCCCCCCCCCC	58.33	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YBEG_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YBEG_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YBEG_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YGNB_SCHPO	nap2	physical	26771498
YHOE_SCHPO	SPBC428.14	physical	26771498
PIL1_SCHPO	pil1	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YBEG_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21; SER-496 AND SER-497,AND MASS SPECTROMETRY.	18257517 [Abstract]