YB7A_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YB7A_SCHPO
• UniProt AC: O14325
• Protein Name: Uncharacterized AAA domain-containing protein C16E9.10c
• Gene Name: SPBC16E9.10c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 779
• Subcellular Localization: Nucleus .
• Protein Sequence: MRRSGTSLSRDLERKIHERLVSLKDTIQQTEIEEWPVSTRRAIQFVQERDMSLRRIKKPILEKVVEKVLDTLKAEVEEKLASSQDLVLVDSDMEEQSDSNLMEVKDTNVINKSITSLWSSPNLKEIDGEDEKKSVGQESITGSAKRKDRRSKTNGSKRQKAEANREPPSDISLSDIGGLDDCINELLELVAMPIKHPEVYQYTGIHPPRGVLLHGPPGCGKTMLANALANELGVPFISISAPSIVSGMSGESEKKVREVFEEAKSLAPCLMFIDEIDAVTPKRESAQREMERRIVAQFLTCMDELSFEKTDGKPVLVIGATNRPDSLDSALRRAGRFDREICLTVPSQDAREKILRTMAKGLKLSGDFDFRQLAKQTPGYVGADLKALTAAAGIIAIKRIFNEISPLNKLDLNSDPRFNELDSDMALDSNDSLPLDHSSIIQRYLNAHPDPLSPEELEPLAICPQDFIEALAKVQPSSKREGFATVPGVSWNNIGALKSIRVELQMAIVQPIKRPELYQSVGISAPTGVLLWGPPGCGKTLLAKAVANESKANFISIRGPELLNKYVGESERAVRQVFLRARASSPCVIFFDELDAMVPRRDDSLSEASSRVVNTLLTELDGLSDRSGVYVIAATNRPDIIDPAMLRPGRLDKTLLVDLPDAHERVEILKTLTKQTPLHEEVNLDVLGRDERCSNFSGADLAALVREAAVTALRSAVFADIASNEPEITQHSALEPIRVTNADFELAFKNIKPSVSDRDRQKYQRLAKRWSSASTNDAD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
91	Phosphorylation	QDLVLVDSDMEEQSD CCEEEECCCCCCCCC	31.23	28889911
97	Phosphorylation	DSDMEEQSDSNLMEV CCCCCCCCCCCCEEE	46.41	28889911
119	Phosphorylation	KSITSLWSSPNLKEI HHHHHHHCCCCCCCC	41.01	25720772
120	Phosphorylation	SITSLWSSPNLKEID HHHHHHCCCCCCCCC	13.26	28889911
134	Phosphorylation	DGEDEKKSVGQESIT CCCCHHHCCCCHHCC	42.41	29996109
139	Phosphorylation	KKSVGQESITGSAKR HHCCCCHHCCCCHHH	19.98	24763107
143	Phosphorylation	GQESITGSAKRKDRR CCHHCCCCHHHHCHH	23.20	28889911
414	Phosphorylation	LNKLDLNSDPRFNEL CCCCCCCCCCCCCCC	57.18	29996109
423	Phosphorylation	PRFNELDSDMALDSN CCCCCCCCCCCCCCC	41.74	25720772
429	Phosphorylation	DSDMALDSNDSLPLD CCCCCCCCCCCCCCC	43.30	25720772
432	Phosphorylation	MALDSNDSLPLDHSS CCCCCCCCCCCCHHH	35.82	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YB7A_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YB7A_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YB7A_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YB7A_SCHPO	SPBC16E9.10c	physical	26771498
YHOF_SCHPO	SPBC428.15	physical	26771498
AFG2_SCHPO	SPBC56F2.07c	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-97 AND SER-120, AND MASSSPECTROMETRY.
PubMed: 18257517